Review and performance of stem cells and tissue engineering in the treatment of pathologies of the nervous

Saeed Abbasi,1,* Roya nazemi,2 Seyed hesam seyed hosseini,3 Fatemeh malekzadeh,4

2. student if master of science of tissue engineering, department of medical engineering central tehran branch,islamic azad univercity,tehran,iran
3. student if master of science of tissue engineering, department of medical engineering central tehran branch,islamic azad univercity,tehran,iran
4. student if master of science of tissue engineering, department of medical engineering central tehran branch,islamic azad univercity,tehran,iran

Abstract


Introduction

Nerve damage affects millions of people around the world, which lowers the quality of life of the infected and causes a lot of economic and social problems. in spite of the self-defense capacity of the peripheral nervous system of the nervous system, new therapeutic approaches and techniques are needed. the limitations and unconventional results of an auto graft transplant in the clinic require replacement therapy.

Methods

The treatment of neurological damage has become new dimensions with the advancement of tissue engineering and the utilization of stem cells and growth factors, which has attracted the attention of researchers and researchers. by examining the performance and results of in vivo and in vitro experiments such as migration testing, angiogenesis, alamar blue, immunization and microscopy, tem and statistical analysis of how to repair, regenerate, and restore peripheral nerves it can be pointed out and monitored to provide optimal results for the reconstruction, regeneration and repair of peripheral nerve damage.

Results

One of the main advantages of these cells is their ability to differentiate into schwann cells. stem cells modulate the immune systems function, helping to form the myelin layer and producing extracellular matrix molecules during environmental nerve repair.

Conclusion

This review is a review of the type and function of stem cells and the progress made by tissue engineering in the treatment of peripheral neuropathic damage. this study aims to treat environmental neurological damage at the earliest possible time, observing international standards, and taking into account the therapeutic issues, and ultimately increasing the quality of life of affected people.

Keywords

Tissue engineering, stem cells, peripheral nerves