• The Association Between Dietary Zinc Intake and Health Status,Including Mental Health and Sleep Quality, Among IranianFemale Students
  • Hossein Hajianfar,1 Negar Mollaghasemi,2,* Rahele Tavakoly,3 Marilyn S. Campbell,4 Mohadese Mohtashamrad,5 Arman Arab,6
    1. sfahan Endocrine and Metabolism Research Center of Nutrition andFood Sciences, Isfahan University of Medical Sciences, Isfahan, Iran
    2. Student Research Committee, School of Nutrition and FoodSciences, Semnan University of Medical Sciences, Semnan, Iran
    3. Department of Nutrition, School of Health, Kerman, University ofMedical Science, Kerman, Iran
    4. Department of Kinesiology and Health Promotion, University ofKentucky, Kentucky Lexington, USA
    5. student Research Committee, School of Nutrition and FoodSciences, Semnan University of Medical Sciences, Semnan, Iran
    6. Department of Community Nutrition, School of Nutrition and FoodScience, Food Security Research Center, Isfahan University ofMedical Sciences, Isfahan, Iran


  • Introduction: Epidemiological studies have suggested that there is an association between diet and mental health. The aim of the current study was to explore the association between dietary zinc intake and risk of depression, anxiety, and sleep quality distortion among female students of the Semnan University of Medical Sciences in a cross-sectional study.
  • Methods: From January through October 2019,142 female students were randomly selected from the Department of Nutrition and Food Science at the Semnan University of Medical Sciences by simple random sampling. Food frequency questionnaires (FFQs) were used to assess participants’ dietary intake over the past 12 months. Depression, anxiety, and sleep quality were examined by the Beck Depression Inventory-II (BDI-II), Beck Anxiety Inventory (BAI), and Pittsburgh Sleep Quality Index (PSQI), respectively. In the analysis, the crude model was adjusted for total energy intake (kcal), while the model was adjusted for energy intake (kcal), age, economic status, physical activity level, serum vitamin D level, and body mass index.
  • Results: Dietary zinc intake is significantly associated with depression (odds ratio (OR) (95% confidence interval (CI)): 2.34 (0.38–4.30)) and anxiety (OR (95% CI): 3.43 (2.36–4.50)), sleep disorders (OR(95% CI): 3.65 (2.16–5.13)), sleep duration (OR (95% CI): 2.62 (0.39–4.86)), and daytime dysfunction (OR (95% CI): 5.31(2.84–7.78)) in the model, as well as sleep delay (OR (95% CI): 1.80 (1.05–2.55)) and mental quality of sleep (OR (95% CI): 1.63(1.10–2.15)) in the crude analysis.
  • Conclusion: This cross-sectional study supports the inverse association between dietary zinc intake and mood disorders, including depression and anxiety, and some indices of sleep disturbance in the Iranian female students. Further cohort or intervention studies are required to draw a firm link between dietary zinc intake and mental health
  • Keywords: Dietary zinc.Depression.Anxiety.Sleep quality.Students