- fabrication of PCL/Gelatin biocomposite with 3D printing and comparison of mechanical properties with electrospinning's sample
-
Soulmaz Sarkari,1,*
1. Islamic Azad University Tehran Science and Research Branch, Tehran, Iran
- Introduction: both the natural polymers (including collagen and gelatin) and synthetic polymers (such as PLGA and PCL) have been commonly used as the condidates for electrospinning and 3D printing. Today;these two way of fabrication scaffolds are very common .obviously ;they have some differences.this research study how they differ in mechanical properties.
- Methods: In the last research, the primitive scaffolds were prepared by FDM 3D printers , for using 3d printers we need to find suitable mode that these are as: Floor temperature: 35 ° C, Nozzle temperature: 160 ° C, Print speed: 1250 mm / min with automatic adjusting fan .after this step; gelatin have been mixed with twice distilled water at a ratio of 0.01 and stirred for 24 hours then polycaprolacton scaffold was sank in the mixture for a while and for crosslinking glutaraldehyde vapor used.
In the light of http://dx.doi.org/10.1080/09205063.2016.1160560 they investigated 5 different ratio of pcl/gelatin properties that the best result in mechanical properties were for 4:1 and 2:1 pcl/gelatin.
- Results: For Investigation of attachment of gelatin on polycaprolactone in 3d printing's scaffolds using scal(figure1) and the figure2 the mechanical properties of two samples in pure and composite form show that mechanical property of scaffold in composite form is more than pure one.
In the other case (electrospinning samples figure3) the best result of mechanical properties are for 4:1 and 2:1 pcl/gelatin, additionally 2:1 sample is more better than 4:1.
- Conclusion: However these two way of fabrication biocomposites are very common and both of them showed acceptable results, depends on where we use the scaffold it could be different .
- Keywords: pcl/gelatin biocomposite - 3D printing - electrospinning - mechanical properties