Introduction: Hypercholesterolemia is one of the modifiable risk factors for atherosclerosis and cardiovascular diseases. The relation of cholesterol in creating coronary heart disease (CAD) has been specified. According to statistics announced by the Ministry of Health and Medical Education, 150,000 deaths due to stroke are recorded annually in Iran, Prevention and treatment of hypercholesterolemia and other lipid abnormalities require reliable data regarding the current prevalence of these abnormalities in the country. This study aims to determine the current prevalence of lipid abnormalities in Tehran.
Methods: In this article, comparisons of HDL-C and LDL-C in men and women between the ages of 45 to 65 years with equal or more than 200 mg/dL cholesterol level have been done. Data were collected according to a standard protocol. It was found that 167 women and 130 men had equal cholesterol and more than 200 mg/dL. After determining the final number of people in each group for statistical analysis using the amount of cholesterol, other parameters evaluated by HDL-C and LDL-C were also collected and statistical analysis was performed, for this purpose comparison of these factors was performed using chi square, t-test, and bar chart in both male and female populations.
Results: Results shows the means of cholesterol level were 230.5 mg/dL in men and 216.5 mg/dL in women, the cholesterol level is more desirable in women compared to men, even in cases above the normal range. The LDL-C study found that the mean LDL-C in men was 140.47mg/dL in the border high range (130-159 mg/dL), but the mean in the female population equal to 122.7 mg/dL is in the above optimal range (100-129 mg/dL). Only 3.07% of men and 25.15% of women had optimal LDL-C level. Also, in investigating HDL-C, women have a more desirable position compared to men. The means of HDL-C level were 40.2 mg/dL in men and 45.2 mg/dL in women. Pearson’s correlation was used to analyze the association between all studied parameters. The values P < 0.05 were considered statistically significant.
Conclusion: The cholesterol level is more desirable in women compared to men, even in cases above the normal range. The comparison of HDL-C and LDL-C in men and women with high cholesterol level has been completed. High LDL-C is the main lipid abnormality in this population. The majority of men in this study did not meet the desired level of LDL-C and HDL-C. Public health preventive policies should be made and implemented to better manage dyslipidemia.
Keywords: atherosclerosis, cardiovascular disease, cholesterol, high density lipoprotein cholesterol, low dens