Introduction: The most general primary brain tumor in adults is gliomas. Gliomas measure a diapason from low to high grade and are graded pathologically on a scale of one to four according to the World Health Organization classification. Grade IV glioma is acknowledged as Glioblastoma.
Glioblastoma (GBM) is a malignant brain tumor that grows quickly by building blood vessels around it and easily damages brain texture. Glioblastoma is not very common but is 20% more probably to develop brain cancer. And 2.5 percent of deaths are due to cancer.
Glioblastoma is ordinary in men and is usually seen in the average age of 64. Glioblastoma starts from astrocyte cells and in adults in the cerebrum (forebrain). Glioblastoma seldom spreads outside the brain, and factors that because glioblastoma include exposure to certain substances, chromosome changes, and family-specific inherited disease.
Because glioblastomas grow quickly, pressure on the brain usually causes the first symptoms. Depending on where the tumor is, it can cause persistent headaches, double or blurred vision, vomiting, loss of appetite, changes in mood and personality, change inability to think and learn, new onset of seizures, and speech difficulty of gradual onset.
A neurologist will give you a complete exam. The complete exam includes sophisticated imaging techniques (which can accurately pinpoint the location of brain tumors.), computed tomography (CT or CAT scan), and magnetic resonance imaging. Magnetic resonance spectroscopy is used to examine the tumor's chemical.)
The Common treatment for recently diagnosed glioblastoma is surgery to remove as much of the tumor as possible, followed by chemotherapy (an anti-cancer drug called temozolomide; TMZ) and radiotherapy.
TMZ is often given concomitantly with radiotherapy (concomitant chemotherapy), and also lasts for about 6 months after radiotherapy (adjuvant chemotherapy).
simultaneously, these treatments are also known as chemoradiotherapy. However, not all people, especially the elderly, are good enough to get a CRT because it can have serious side effects.
Methods: The present study was considered the first joint research work by this group. So, to start the research, we studied and searched online resources. Research has been done on various methods that prevent, diagnose and treat glioblastoma. To collect information, we referred to various articles in the period 2017-2021. We reviewed the collected material in several online sessions. Eleven articles have been used to compile this collection, which according to the previous information and with the knowledge of four articles have been rejected and the necessary conclusions have been made from eight articles in total. After discussion and exchange of views, the final text was prepared.
Results: Glioblastomas are malignant tumors with grade 4. A large portion of the cells in these tumors are constantly proliferating and dividing. These cancer cells are nourished by abundant and abnormal blood vessels.
Glioblastoma can present as a grade 4 tumor from the beginning and there is no sign of lower-level tumors. These tumors are the most common type of glioblastoma, affecting most older patients, and are more aggressive than other tumors.
Glioblastomas can be difficult to treat because of the resistance of some cells to treatment. For this reason, a glioblastoma treatment plan may include several treatment strategies.
Conclusion: The glioblastoma brain tumor is a type of brain cancer.
The most common type of malignant brain tumor in adults is glioblastoma. This tumor is highly invasive, meaning it has a high growth rate and spreads rapidly.
Brain tumors that originate from astrocyte cells occur mostly in adults in the frontal lobe of the brain.
Glioblastoma brain tumor grows by creating blood vessels around it and easily destroys other healthy brain tissue.
Brain tumors are not very common, but if they occur in less than 20% of cases, it may be glioblastoma, which is likely to cause a tumor.
Glioblastoma is more common in men than women and increases with age.
Because glioblastoma grows swiftly, the first complication is pressure on the brain. Depending on what area of the brain the tumor is in, any of the complications mentioned in the article may occur.
The goal of tumor treatment is to control growth and metastasis and help eliminate the complications of the tumor.
There are several treatment strategies for brain tumors, the most important of which is surgery.