Introduction: Sexually transmitted infections (STIs) are a serious health care problem in the world, both in industrialized and in developing countries, they are increasing among youth and can cause acute and chronic disease also social and economic problems but most of them are preventable and treatable.
Methods: 20 articles published between 2018 and 2021 were selected in PubMed and reviewed.
Results: Findings indicate that Knowledge of STI was the low and major source of information was from movies and the internet and associated with age, level of education, employment status, attitude, the country they lived and preventive practices of the respondents. Developing countries undergo a great burden. In Islamic societies, sexual issues are sensitive and rarely discussed. Significant positive associations were shown between knowledge of safe sex by youth living with other people, those who had studied family planning and had religious beliefs reflecting acceptance to using birth control. HIV was the most known than other STIs. Some studies found that males had better knowledge than females the observed difference was not statistically significant. some studies showed that those with less knowledge had a higher risk of sexual behaviors.
Conclusion: young people had low knowledge about STIs in most studies, It is necessary to emphasize youth as the most vulnerable group. Increasing the awareness of STI starting from school age may help young people to live healthier and we need media campaigns to teach young adults who do not attend university or school.