Introduction: Papilloma virus is the causative agent of warts in humans. Papillomavirus is from the Papovaviridae family. Wart treatment is often difficult and long-term. Tomato is a plant with high antioxidant properties that is used in the treatment of many diseases. Tomato stems are used in the treatment of warts in northwest of Iran. In this study the therapeutic effect of tomato stalk (Solanum lycopersicum) on warts was investigated.
Methods: The study was performed by culture of HPV virus and the use of human samples. A total of 15 human samples were randomly divided into three groups. 5 patients were tested by tomato stalk and 5 by tomato stalk extract. Five control samples were considered. Patients were evaluated for side effects after completing the course for two years. On the other hand, in the cell culture assay, breast cancer cells were cultured as basal medium. The effect of tomato stem extract on HPV virus and cancer cells was investigated.
Results: At the end of the course, three people in the first group were completely cured within a week and two people in the first group were cured within ten days. Also, two people in the second group were completely cured within a week, one was cured within eleven days. Two recovered completely in fourteen days. One in the third group recovered within two months. Since the third group did not use any therapies, the person's recovery could be related to the person's immune system. Also in laboratory samples, about 72% of the viruses cultured in the vicinity of tomato stem extract were killed. Nearly 69% of cancer cells are prevented from growing. No improvement was seen in the control group during the experiment.
Conclusion: Research has shown that tomato stems have an effective and rapid role in removing warts. Also, tomato stems have been effective in preventing the growth of HPV. Due to the antioxidant and antitumor properties of tomatoes, it appears that these properties in tomato also play an important role in wart destruction and HPV growth.