• The effect of antibacterial factors of Diospyros lotus leaf and fruit extract on pathogenesis: A review study
  • Alam Ara Gholami,1 Ali Ahmadi ,2,*
    1. Assistant Professor, Department of Biological Sciences and Technologies, Islamic Azad University, Sari Branch, Sari, Iran
    2. Student, Department of Biological Sciences and Technologies, Islamic Azad University Sari Branch, Sari, Iran


  • Introduction: Persimmon genus with the scientific name of Ibnaseh has 6 genera and 300-400 species. In the natural habitats of Iran, the genus Essence has only one genus called Diospyros lotus with two species, which include: Diospyros lotus and Diospyros tomatoes. This study aimed to investigate the effect of antibacterial agents of Diospyros lotus leaf and fruit extract on pathogenesis bacteria.
  • Methods: This review study was conducted in 2021 by searching for keywords such as antibacterial agents, Diospyros lotus, plant extracts, and pathogenesis microorganisms invalid databases.
  • Results: Based on the study of various articles, the results show that today, the use of multiple antibiotics due to lack of proper diagnosis, causes the emergence of more than one type of antibiotic-resistant in the patient. On the other hand, it should be noted that the limited duration of an antibiotic can be used as the drug of choice for the treatment of infections caused by resistant bacteria.
  • Conclusion: According to the results of the mechanism, the protective effect is related to the presence of antioxidant compounds such as flavonoids and naphthocytones in the plant, which neutralizes the toxic and radical composition of the pyrrolizidine alkaloid Sensivulgaris.
  • Keywords: Antibacterial agents, Diospyros lotus and pathogenesis microorganisms