مقالات پذیرفته شده در ششمین کنگره بین المللی زیست پزشکی
Investigating possible mental injuries and brain injuries of COVID-19
Investigating possible mental injuries and brain injuries of COVID-19
Saeed feyzbabaei cheshmeh sefid,1,*
1. Bachelor of vet Laboratory Science, Faculty of Para Veterinary Medicine, Ilam University - Iran - Iran
Introduction: With the spread of the covid-19 pandemic, scientists started researching this issue to clarify the different angles of the infection of this unknown and new virus. In addition to clarifying the occurrence of lung infection, signs of some psychological and physiological damage were proven. Our study presents the results of reports and articles from around the world about the possibility of psychological and physiological damage of covid-19 on the nervous system. In this study, 125 related articles until June 2021 from databases such as Scopus, Pubmed, Web of Science, Google Scholar, and Google, and using keywords covid-19 brain damage, covid-19 infection, disease imaging findings covid-19, mental health, and covid-19 were extracted. Articles that were not the purpose of this study were excluded from the research process and finally, 43 articles were used. Due to the possibility of the SARS-COV virus not passing through the blood-brain barrier, a specific cause for neuropathological injuries and brain encephalopathies has not yet been introduced, and this mechanism is still unknown. An increase in the volume of the gray matter of the brain in the hippocampus and the olfactory bulb and an increase in anisotropy in the white matter fraction of the brain were reported in people who were suffering from the acute form of this disease compared to people who were not suffering from the corona. And psychologically, the occurrence of some styles of Symptoms such as rumination and anhedonia were confirmed in this disease and in affected people.
Methods: In this study, 125 related articles until June 2021 were found from Persian and English databases such as Scopus, Pubmed, Web of Science, Google Scholar, Google, and using the keywords covid-19 brain injury, covid-19 infection. Imaging data of covid-19 disease, mental health and covid-19 were extracted. The articles that were not the purpose of this study were excluded from the research process and finally, 43 articles were used in our research.
Results: The SARS-COV2 virus is a beta corona virus with a similar structure to its predecessor, SARS-COV, which has a genetic similarity of 70% with SARS-COV and more than 50% with the Middle East Respiratory Syndrome virus (MARS) (14). By binding to angiotensin (ACE 2) receptors on the surface of lung epithelial cells, the virus implants in this tissue and causes symptoms of viral infections such as viral pneumonia and symptoms similar to MARS and SARS-COV. (15).
Conclusion: Considering the physiological and immunological changes in patients with the new coronavirus and the emergence of mental disorders, as well as the proof of the presence of this virus in CNS fluids, it is possible to recommend In people who have acute symptoms, MRI imaging must be used after recovery to check the possibility of brain damage in these patients, and also in hospitalized patients with acute symptoms, this imaging must be used for CNS in case of any changes .in the brain. The central nervous system can quickly control or treat these symptoms before certain events occur. Also, the importance of health and mental health of people who visit high-risk places such as hospitals and public places, such as medical staff and people who visit the market, doubles. It is hoped that the results of this study will be used by all people, especially the treatment staff so that post-corona mental injuries can be prevented.