Antimullerian hormone and polycystic ovaries: A systematic review study
Antimullerian hormone and polycystic ovaries: A systematic review study
Nasim Sadat Pajohanfar,1,*Saeede Mehrabadi,2
1. Department of Midwifery, Faculty of Medicine, Student workgroup of Social Determinants of Health Research Center, Gonabad University of Medical Sciences, Gonabad, Iran. 2. Department of Midwifery, Department of Midwifery, School of medical, Sabzevar University of Medical Sciences, Sabzevar, Iran
Introduction: Polycystic ovary syndrome (PCOS) is a complex endocrine disorder with reproductive, psychological, and metabolic health consequences. Its prevalence has been reported up to 5-10%.
Since various studies have suggested the relationship between the Antimullerian hormone and polycystic ovarian, this hormone can be highly beneficial in diagnosing this disease.
Methods: To get relevant studies from the English and Persian databases such as PubMed, Scopus, Web of Science, Iran Medex, SID, and Magiran, the English and Persian keywords (Polycystic ovaries and Antimullerian hormone with all possible search combinations) have been searched.
Results: Out of 1680 articles, 7 studies (1 cross-sectional 3 cohorts 3 case-control) were eligible according to the study criteria. All studies were evaluated based on the STROBE index. Our analysis revealed that higher levels of Antimullerian hormone could play a vital role in increasing the risk of polycystic ovaries. There was one study that suggested there is no relationship between AMH and PCOs.
Conclusion: The results of most studies showed a significant association between higher levels of Antimullerian hormone and polycystic ovaries. While a study has reported conflicting results. Therefore, it is highly recommended that further studies should be conducted in this area.