Antifungal effect of Artemisia austriaca extract on common Candida species(albicans, glabrata, parapsilosis, krusei) in Iran
Antifungal effect of Artemisia austriaca extract on common Candida species(albicans, glabrata, parapsilosis, krusei) in Iran
Shadi Shahriyari,1,*Behin Omidi,2Solmaz Shahla,3
1. Department of Biology, Faculty of Basic Science, Central Tehran Branch, Islamic Azad University, Tehran, Iran. 2. Department of Biology, Faculty of Basic Science, Central Tehran Branch, Islamic Azad University, Tehran, Ira 3. Department of Biology, Faculty of Basic Science, Central Tehran Branch, Islamic Azad University, Tehran, Iran
Introduction: Candida species are one of the most common fungal diseases. Today, drug resistance is observed in fungi, especially in candida species, so researchers are looking for suitable alternatives; one of these choices is plant extracts because Plants have different metabolites with strong antimicrobial effects. In this study, we used Artemisia austriaca extract against a group of pathogenic fungi.
Methods: Plant extraction was performed using the Soxhlet apparatus. Candida samples were randomly chosen. The resistance and sensitivity of the candida species to plant extracts were investigated by the disk diffusion method. MIC was done by microdilution method; finally, MBC was also measured.
Results: According to the results obtained, among the studied species, the best antifungal effect was observed on Candida albicans. The growth inhibition zone of this fungus was 21±0.5mm. The MIC of the plant in Candida albicans was 31.25mg/ml, and MBC was 62.5mg/ml.
Conclusion: The results show that artemisia extract has a significant antifungal effect. Artemisia extract has the ability to have a more substantial antifungal effect against common Candida species. The present study indicates that Artemisia extract can be used in control and prevention models.