Elham Zendedel,1,*Shiva Asadpour,2
1. Tissue Engineering & Applied Cell Sciences, Shahrekord University of Medical Sciences 2. Tissue Engineering & Applied Cell Sciences, Shahrekord University of Medical Sciences
Introduction: Bioglass® is a bioactive implant that promotes bone regeneration. This substance undergoes a sequence of surface reactions in an aqueous environment, resulting in the production of a hydroxycarbonate apatite (HCA) surface layer.
Methods: The attachment and proliferation of osteoblasts on the glass surface, as well as the release of soluble silica, are caused by the creation of this layer and the release of soluble silica. Particulate Bioglass® has been demonstrated to have a significant antibacterial effect on oral microorganisms, particularly those linked to caries and periodontal disease.
Results: When Bioglass® is used in periodontal applications, its antibacterial property may help to lower the risk of bacterial colonization. By inserting nano-bioceramic particles such as nano bioglass (nBG) into the scaffold, a biomimetic scaffold that closely mimics the extracellular matrix of the bone was created.
Conclusion: According to several studies, scaffolds with nBG are better options for orthopedic and periodontal tissue engineering applications.