مقالات پذیرفته شده در هفتمین کنگره بین المللی زیست پزشکی
The role of human papillomavirus vaccines And treatment in cervical cancer review article
The role of human papillomavirus vaccines And treatment in cervical cancer review article
haniye fayezi,1,*katayoun aliyari,2
1. department of microbiology,central tehran branch,islamic azad university,tehran iran 2. department of molecular genetics, tehran branch, islamic azad university,tehran,iran
Introduction: Viral infections are responsible for 15-20% of human cancers. Infection with oncogenic viruses can increase different stages of carcinogenesis. HPV is the most common sexually transmitted infection (STI), and about 15 types are associated with cancer. Despite effective screening methods, cervical cancer remains a major public health problem. Continuous human papillomavirus infection is the main cause of cervical cancer, which is the main cause of cancer-related deaths among women worldwide. The best strategy to reduce the incidence of cervical cancer is through the administration of HPV vaccines along with routine cervical screening. The HPV vaccine is very important for public health. The present study aims to investigate the role of the vaccine in preventing HPV and cervical cancer.
Methods: Clear evidence from randomized trials and population-based studies suggests that vaccination against human papillomavirus reduces the incidence of cervical cancer. At present, 3 types of vaccines have been introduced, the 4-strength Gardasil vaccine is more recommended. Studies show that the vaccine causes cervical cancer.
Results: Developed countries have reduced the challenge of cervical cancer by introducing structured screening programs and recently the HPV vaccine. Countries that have successfully introduced national HPV vaccination programs are on track to eliminate cervical cancer within the next few decades.
Conclusion: This summary deals with the main causes of cervical cancer, high-risk strains of HPV, and this type of malignancy can be prevented. Knowledge of HPV prevalence and type of distribution can help in the successful implementation of the vaccination program.