مقالات پذیرفته شده در هفتمین کنگره بین المللی زیست پزشکی
comparing chemotherapy plus Radiotherapy versus Radiotherapy alone in lung cancer
comparing chemotherapy plus Radiotherapy versus Radiotherapy alone in lung cancer
Zahra Aghababaie,1,*Mansoreh Azadeh,2mohammad Rezaie,3
1. international azad university of Najaf abad 2. Zist fanavari novin biotecnology institue isfahan iran 3. Zist fanavari novin biotecnology institue isfahan iran
Introduction: Lung cancer is one of the most common and deadly cancers. Chemotherapy and radiotherapy are the main treatment modalities for this disease. However, there is still much debate regarding the optimal combination of chemotherapy and radiotherapy. In this paper, we aim to review studies that have compared the effects of chemotherapy plus radiotherapy versus radiotherapy alone for the treatment of non-small cell lung cancer.
Methods: For this systematic review, we will search for studies published up to 2020 in PubMed, Scopus and Web of Science. Included studies should be randomized controlled trials that divided non-small cell lung cancer patients into two groups of chemotherapy plus radiotherapy and radiotherapy alone. The main outcomes assessed will be overall survival and progression-free survival.
Results: Preliminary findings show that chemotherapy plus radiotherapy significantly improves overall survival and progression-free survival compared to radiotherapy alone in patients with non-small cell lung cancer. However, these findings need more thorough statistical verification.
Conclusion: Given the results obtained so far, chemotherapy as an adjunct to radiotherapy appears beneficial for the treatment of non-small cell lung cancer. However, further higher quality studies are required before more definitive conclusions can be made. Future studies should also focus on specific chemotherapy regimens and their timing with radiotherapy.