• Cytomegalovirus and its relationship with HIV
  • Amirreza Normohammadi,1,* Arefeh Behfarrad,2 Rezvan Jahani,3 Aida Shadel,4
    1. Undergraduate student, Department of Microbiology Faculty of Advanced Science & Technology Tehran Medical Sciences, Islamic Azad University, Tehran, Iran
    2. Undergraduate student, Department of Microbiology Faculty of Advanced Science & Technology Tehran Medical Sciences, Islamic Azad University, Tehran, Iran
    3. Undergraduate student, Department of Microbiology Faculty of Advanced Science & Technology Tehran Medical Sciences, Islamic Azad University, Tehran, Iran
    4. Undergraduate student, Department of Microbiology Faculty of Advanced Science & Technology Tehran Medical Sciences, Islamic Azad University, Tehran, Iran


  • Introduction: Herpes viruses are one of the groups of viruses that are double-stranded DNA. This group can make infection in the host body for the whole life. They include viruses like Cytomegalovirus, Epstein-Barr virus, B virus and etc. Among the herpes viruses family, CMV is the largest one . CMV like other viruses can make infection in the host body . CMV infection and its disease are prevalent and common about 36% in 6-11 year olds and about 90% in 80-year-olds. Sometimes the symptoms of CMV infection can be controlled by a powerful immune response therefore the symptoms can be concealed or the symptoms are mild .
  • Methods: This study was conducted from February 11 to March 18 at the Beast Hospital with 149 HIV-positive patients, including 81 men and 68 women. (Table 1) To perform the test, approximately 10 ml of blood was taken from everyone using a 10-syringe, and after examining IgG by CMV antibody test chemiluminescence by Roche Cobas device, it was found that 65.77% of the studied patients, i.e. 98 people, including 67 men and 31 women were shown CMV IgG positive. (Table 2)
  • Results: In this study, we examined 149 patients who were previously confirmed HIV-positive to investigate Cytomegalovirus Seroprevalency. These people included 81 men and 68 women, which are shown in the table1 by percentage After taking a blood sample and performing the CMV Antibody chemiluminescence test, we found that 98 of the 149 patients in our study, that is, 68.77% of the patients, were CMV IgG positive(Table 2), 67 of them were men (44.9%) and 31 were women (20.8%).
  • Conclusion: The spread of the human immunodeficiency virus (HIV), which spreads sporadically from human to human, was linked in the early 1900s . At one time, gay men came increasingly popular in megacity centers, and advanced and unexplainable safety led to the spread of the contagion around the world in the late 1900s . Two years later, what was reportedly finally known as AIDS, scientists discovered the virus that causes the disease: HIV.
  • Keywords: HIV / CMV / CMV IgG