• The role of snp genes related to Alzheimer's disease as biomarkers in the early diagnosis of this disease
  • shaghayegh mehdizadeh ,1,*


  • Introduction: In this article, we want to prevent the occurrence of Alzheimer's by knowing the SNPs of genes related to Alzheimer's ، Alzheimer's disease (AD), an extremely common neurodegenerative disorder of the older generation, is one of the leading causes of death globally.The etiology of Alzheimer’s is complex, with numerous environmental and genetic factors contributing to the disease.Genome-wide single nucleotide polymorphism (SNP) data are now quickly and inexpensively acquired، Alzheimer's disease is a neurodegenerative disorder with a slow onset and slow progression that occurs in middle age, so by knowing the snp genes of this disease, it is better to start treatment from a young age to prevent its occurrence. Finally, we offer some recommendations in areas where the field can rapidly advance towards precision interventions that leverage the ideas of protection and resilience for the development of novel therapeutic strategies
  • Methods: literature review
  • Results: There is no definitive treatment for Alzheimer's disease yet, so we must find a way to prevent its occurrence at a young age, one of which is the recognition of SNPs.
  • Conclusion: The correlation between genetic and functionality data may have an impact on several aspects of disease presentation and therapy, helping in prediction pattern of AD presentation and treatment efficacy. As a consequence it may lead to better patients quality of life and longer periods of self- sufficiency
  • Keywords: Alzheimer’s disease, genetic polymorphisms (SNPs). Early diagnosis of the disease ABCA7, APOE, TRE