مقالات پذیرفته شده در هفتمین کنگره بین المللی زیست پزشکی
Prenatal Stem Cells: A Promising Resource for Craniofacial Bone Tissue Engineering
Prenatal Stem Cells: A Promising Resource for Craniofacial Bone Tissue Engineering
Samane Nouri,1Saman Hakimian,2,*
1. Bachelor of Biomedical Engineering , Payam Noor University Yazd Branch 2. M.sc student of Microbiology Islamic Azad University Central Tehran Branch , Iran ,Tehran
Introduction: The articles explore the potential application of perinatal stem cells in tissue engineering for the regeneration of craniofacial bone. Recent improvements in tissue regeneration in bone defects demonstrate the limits of existing techniques used to restore cranial bone abnormalities and highlight the need for novel stem cell-based procedures.
This article talks about three types of stem cells: adult mesenchymal stem cells (MSCs), embryonic stem cells (ESCs), and induced pluripotent stem cells (iPSCs). All of these stem cells can create bones.
These sources, however, have their own drawbacks, such as scarcity, invasive obtaining methods, and concerns about ethics.
Such stem cells are a promising source for tissue engineering as they have unique features. They have properties identical to adult stem cells and ESCs, show immunoprivileged status, and have an extensive range of multipotent plasticity.
Methods: Breakthroughs and issues regarding stem cell-based craniofacial bone reconstruction are discussed by the researchers.
Perinatal stem cells have many advantages. These advantages include their large quantity, ability to multiply, and capability to transform into different types of cells. These characteristics are currently being highlighted because of their potential in regenerating craniofacial bone tissue.
Results: In conclusion, perinatal stem cells hold great promise for extensive use in craniofacial bone tissue engineering. Scientists suggest that with further research and development, perinatal stem cell-based strategies can be applied for customized and functional clinical reconstruction of craniofacial bone defects.
Conclusion: Perinatal stem cells are commonly seen as a practical and viable option for allogeneic transplantation This is mainly due to their low immunogenicity and their significant potential to affect the immune system.