مقالات پذیرفته شده در هفتمین کنگره بین المللی زیست پزشکی
Characterization and Evaluation of Nanofiber Materials at wound dressings
Characterization and Evaluation of Nanofiber Materials at wound dressings
masoud karimi,1,*Azar Ghavimi Shamekh,2
1. Department of Medical Biotechnology, School of Sciences and Advanced Technologies, Hamadan University of Medical Sciences, Hamadan, Iran 2. Department of Education and Research of Blood Transfusion Organization, Hamadan, Iran
Introduction: Nanofiber materials have high surface area-to-volume ratios, and their properties differ significantly from those of bulk materials. Therefore, their characterization and evaluation require different techniques than materials. Nanofiber materials can be characterized by various such as scanning electron microscopy, transmission electron microscopy, Fourier transform infrared spectroscopy, X-ray diffraction, and Thermogravimetric analysis. These techniques describe key structural and physicochemical properties such as size, morphology, surface area, porosity, and specific surface area The evaluation of nanofiber materials is mainly based on their performance concerning special applications such as filtration, catalysis, sensors, and wound. Materials selection, synthesis, analyses, and characterization are essential for successful nanofiber materials. Understanding the characterization and evaluation techniques for nanofiber materials is critical for their efficient use in applications.
Methods: Nanofiber materials are produced by various methods, including electroinning, template synthesis, self-assembly, and phase separation. These have a broad range of applications in various fields, including biomedical, energy storage, filtration, and sensors. In recent years, there has been an increasing interest in the characterization and evaluation of nanofiber materials understand their fundamental properties and optimize their performance for specific applications. Different characterization techniques, such as SEM, TEM, AFM, XRD, and FTIR, are used to examine the nanofiber morphology, properties, and structure. The evaluation of nanofiber materials involves testing their mechanical, electrical, thermal, and optical properties, as well as their biocompatibility toxicity.
Results: The fabricated nanofiber wound dressings, with their enhanced properties and characteristics, are expected to have a significant impact on wound healing. Due to their more orderly arrangement and improved structural integrity, the nanofiber wound dressings demonstrate enhanced mechanical strength, moisture retention capability, gas exchange capability, and exudate absorption capacity compared to traditional wound dressings. These properties contribute to creating a favorable environment for wound healing by providing adequate support, moisture regulation, and oxygen exchange, which are crucial for the proliferation and migration of cells involved in the wound-healing process.
Conclusion: In conclusion, nanofiber wound dressings have shown promising results in terms of their impact on wound healing and have been extensively explored for their application in medicine. However, there are still challenges to overcome, such as the need for further clinical trials and validation of their effectiveness, addressing the cost-effectiveness of large-scale production, optimizing fabrication techniques, and exploring functionalization methods and integration of nanoparticles or nanocomposites.
Further research should be conducted to address these limitations and advancements in the field of nanofiber wound dressings have the potential to revolutionize the way we treat and heal wounds. As a result, this could lead to improved patient outcomes and reduced healthcare costs in the future. Further research and development efforts are needed to optimize the fabrication techniques of nanofiber wound dressings in order to enhance their mechanical strength and structural integrity. Furthermore, functionalization methods should be explored to enhance the properties of nanofiber wound dressings, such as incorporating growth factors or bioactive molecules for enhanced tissue regeneration. Additionally, the integration of nanoparticles or nanocomposites into nanofiber wound dressings should be further investigated to enhance their therapeutic capabilities, including antibacterial.