• The Application of Taurine in Wound Healing
  • Hamid Reza Ghaderi Jafarbeigloo,1 Fariba Noori,2 Zahra Abpeikar,3 ali abbasi,4 Arash Goodarzi,5,*
    1. Department of Tissue Engineering, School of Advanced Technologies in Medicine, Fasa University of Medical Sciences, Fasa, Iran
    2. Department of Tissue Engineering, School of Advanced Technologies in Medicine, Fasa University of Medical Sciences, Fasa, Iran
    3. Department of Tissue Engineering, School of Advanced Technologies in Medicine, Fasa University of Medical Sciences, Fasa, Iran
    4. Department of Physiology, Fasa University of Medical Sciences, Fasa, Iran
    5. Department of Tissue Engineering, School of Advanced Technologies in Medicine, Fasa University of Medical Sciences, Fasa, Iran


  • Introduction: The drug delivery system enables the release of the active pharmaceutical component to achieve an efficient programmed response. Taurine is a free amino acid that plays an important role in some main biological processes and has the potential to be encapsulated and delivered to specific tissues or cells involved in angiogenesis for tissue engineering approaches. One of the major paths in wound healing is preparing conditions that help angiogenesis.
  • Methods: An electronic search was done in the PubMed, Scopus, and Google Scholar databases from January 2016 to September 2023 with the keywords taurine, tissue engineering, and wound healing. A combination of keywords was done using Boolean drivers AND and OR, and then the data analysis was done precisely.
  • Results: It is adopted that taurine has some antioxidant and anti-inflammatory properties, which can indirectly support angiogenesis, and there is limited research on its direct effects on blood vessel formation. Taurine could have beneficial effects in various conditions. Additionally, recent studies showed that taurine plays a vital role in the aging process, even though by reducing histamine level degranulation of the mast cells
  • Conclusion: Finally, by a glimpse, it is known that taurine may have the potential to be used in bioprinting, the ability to be encapsulated in a nanocarrier, and cell therapy in tissue engineering. Despite proven facts about the drug delivery system and taurine separately, It is necessary to do more research to find challenges and solutions. On the one hand, whether taurine can be used directly on wounds or not, and on the other hand, strong in vitro or in vivo studies should be designed and carried out.
  • Keywords: taurine, tissue engineering, and wound healing