Introduction: Shigellosis is the most common in developing countries and this disease is the second cause of death in children under 5 years of age (11%). on of the common causes of this disease is malnutrition, and the problems that arise as a result of this disease are low physical and mental growth. due to the resistance of shigella bacteria to antibiotics, Shigellosis is very worrying as an inflammatory diarrhea agent in Iran therefore, the aim of this study is to investigate the pattern of antibiotic resistance in Tehran
Methods: First, we use MAC and XLD agar, then take created colony to the gallery tests to determine the serotypes of shigella bacteria, we perform a serological test, and if the agglutination results is positive mass is formed. and finally, it is Time to perform an antibiogram test to detect the sensitivity of shigella bacteria strains to antibiotics
Results: the shigella strains were isolated from 36 patients with bloody diarrhea (10%). overall, 36% isolates were positive for shigella spp. of which 16 (44.44%) serotypes were identified as shigella flexeneri, 10 (27.77%) serotypes were identified as Shigella sonnei, 2 (5.55%) serotypes were identified as Shigella boydii and 8 (22.22%) serotypes were identified as Shigella dysenteriae. shigella flexeneri is the most common and antibiotic susceptibility test revealed that the lowest resistance percentage was related to ciprofloxacin and Cefixime that were the best antibiotics against Shigella isolates
Conclusion: we concluded that strains shigella bacteria from contaminated fecal-oral route and contaminated water and food be transferred. and this is one of the causes of diarrhea in Tehra. since the drug resistance pattern of Shigella differs geographically and over time within a country, continuous and regular surveillance program is necessary