Detection of Acinetobacter baumannii strains isolated from Intensive Care Units (ICU)

Detection of Acinetobacter baumannii strains isolated from Intensive Care Units (ICU)
Parisa behshood,^1,* Fateme Talebi varnosfaderani,² Elahe Tajbakhsh,³
1. PhD, Department of Microbiology, Shahrekord Branch, Islamic Azad University, Shahrekord, Iran
2. PhD, Department of Microbiology, Shahrekord Branch, Islamic Azad University, Shahrekord, Iran
3. PhD, Department of Microbiology, Shahrekord Branch, Islamic Azad University, Shahrekord, Iran
Introduction: Recently, A. baumannii appears significantly in the form of endemic and epidemic in hospitals. In the clinical setting, A. baumannii is extremely dangerous, due to it is the ability to colonize and infect severely immunocompromised patients in ICUs. The aim of this study was to determine the Detection of Acinetobacter baumannii strains isolated from the Intensive Care Units (ICU) of Isfahan
Methods: During one one-year period (2021-2022), 200 samples of Suspected Acinetobacter baumannii were assembled from the ICUs of Isfahan hospitals. A. baumannii was confirmed by conventional phenotypic and biochemical experiments. For definitive diagnosis A. baumannii PCR assay was performed for OXA_51-like gene. The susceptibility of isolates was determined by the standard disk diffusion technique according to CLSI
Results: In this study, 100 isolates were Confirmed as A. baumannii. The antimicrobial patterns of isolates showed that 95% to imipenem, 90%Cefepime, and meropenem, 85% to trimethoprim-sulfamethoxazole, 80% to Ceftazidime, 70% to Tetracycline, 40% of isolates were resistant to Amikacin. All isolates were resistant to Ciprofloxacin
Conclusion: In this study A. baumannii, was high in resistance to antimicrobial agents. Strategies to control these strains in the treatment center should be implemented.
Keywords: Acinetobacter baumannii.Intensive Care Units. Antimicrobial agents