• Unlocking the potential of nutraceutical in celiac disease pathogenic cascade
  • Mahtab jahdkaran,1 Nastaran Asri,2 Mohammad rostami-nejad,3,* Hadi esmaily,4
    1. Department of Clinical Pharmacy, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran
    2. Gastroenterology and Liver Diseases Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran
    3. Gastroenterology and Liver Diseases Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran
    4. Department of Clinical Pharmacy, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran


  • Introduction: Celiac Disease (CD) stands as the most typical hereditary food-induced intolerance worldwide. CD is a type of enteropathy that is chronic and caused by an autoimmune response. It typically affects individuals who are genetically susceptible, and it is often triggered by consuming gluten proteins from wheat, barley, and rye . Among autoimmune diseases, a highly prevalent one is celiac disease which affects 1% of people globally and is gradually increasing. Currently, the only known effective treatment for celiac disease is following a gluten-free diet (GFD). In the present study we reviewed the potential of different nutraceuticals in celiac disease pathogenic cascade.
  • Methods: A critical review article which hypnotize about potential of nutraceutical in celiac disease pathogenic cascade
  • Results: Phytochemicals, PUFAs, amino acids, vitamins, minerals were found to be potential for affecting celiac disease pathogenic cascade.
  • Conclusion: A regimen concluding different nutraceutical could be beneficial in celiac disease patients.
  • Keywords: Celiac- Nutraceuticals- Phytochemicals-Micronutrient