• Pioneering the Application of Nanotechnology in Enhancing Fertility Treatments: A Novel Approach in Women's Reproductive Health
  • Sonia Fathi,1,* Reza Maleki baladi,2
    1. Department of Advanced Sciences and Technologies in Medicine, School of Medicine, North Khorasan University of Medical Sciences, Bojnurd 9414974
    2. Young Researchers and Elite Club, Bojnourd Branch, Islamic Azad University, Bojnourd, Iran;


  • Introduction: The sphere of Women's Reproductive Health, particularly fertility treatments, is shifting under the influence of nanotechnology. While conventional therapy approaches deliver mixed results, primarily due to biological complexities and safety concerns, nanotechnology is carving a promising path for significant breakthroughs in fertility treatments. This emerging field could be revolutionary due to the unique properties of nanoparticles, like their reactive nature and high surface-to-volume ratio, which are crucial for effective drug delivery systems capable of surpassing biological barriers, such as the placental barrier.
  • Methods: In this review, studies detailing the practical implications of nanotechnology, its engagement in medicine, particularly in treating placental dysfunction and infertility, were critically examined. Examining such a wide array of source data enabled us to offer a holistic insight into nanotechnology's application in fertility enhancement. Key factors analyzed involved the physical, chemical, biological, and functional properties of nanoparticles, focusing on their potential as targeted drug delivery systems to treat reproductive health issues.
  • Results: The collected reports and analyses reflect an encouraging potential for nanotechnology to transform fertility treatments. The nanoparticles exhibited promising characteristics for biomedical applications, including size and conformation, which are instrumental in determining their trajectory dynamics. More importantly, nanoparticles exhibited an impressive ability to deliver therapeutic agents with precision, reducing associated risks to mothers and fetuses. Other minimized risks include adverse drug reactions and organ toxicity, given the targeted action of nanoparticles.
  • Conclusion: Indeed, nanotechnology stands as a beacon of hope in dealing with complex reproductive health issues. It combines the principles of biology, physics, and chemistry in an innovative way to improve fertility treatments. However, this revolutionizing field still necessitates further exploration, evaluation and clinical trials to establish optimal nanoparticles for safe and effective application in fertility treatments. The small-scale success stories of nanomedicinal applications provide a strong foundation and build a promising picture of nanotechnology's role in enhancing fertility treatments, presenting novel pathways in Women’s Reproductive Health.
  • Keywords: Nanotechnology Fertility treatments Women’s reproductive health Nanoparticles Targeted drug delivery