• Nosocomial infections resistant to Pseudomonas review article
  • Mahla Behnam Hossein Pour,1 Saman Hakimian,2,*
    1. M.sc student of industrial Microbiology Islamic Azad University Central Tehran Branch,Iran,Tehran
    2. M.sc student of Microbiology Islamic Azad University Central Tehran Branch,Iran,Tehran


  • Introduction: Nosocomial infections are also known as hospital-acquired associated infections.The agents that are usually involved in hospital-acquired infections include Streptococcus spp., Acinetobacter spp., enterococci, Pseudomonas aeruginosa, coagulase-negative staphylococci, Staphylococcus aureus, Bacillus cereus, Legionella and Enterobacteriaceae family members, namely, Proteus mirablis, Klebsiella pneumonia, Escherichia coli, Serratia marcescens.
  • Methods: Material methods: Nosocomial pathogens can be transmitted through person to person, environment or contaminated water and food, infected individuals, contaminated healthcare personnel's skin or contact via shared items and surfaces. Mainly, multi-drug-resistant nosocomial organisms include methicillin-resistant Staphylococcus aureus, vancomycin-resistant enterococci, Pseudomonas aeruginosa and Klebsiella pneumonia, whereas Clostridium difficile shows natural resistance.Excessive and improper use of broad-spectrum antibiotics, especially in healthcare settings, is elevating nosocomial infections.
  • Results: Results:This study was planned to delineate prevalence of MDR P. aeruginosa in nosocomial infection patients, and to screen for ESβLs producing P. aeruginosa with typing of P. aeruginosa isolates in Menofia University Hospitals (MUH), Egypt. Our study included 287 inpatients admitted to Menoufia University Hospital and having different nosocomial infections. Samples from medical staff and from hospital environment were collected. Antibiotyping of P. aeruginosa isolates were determined. MDR and ESBLs P. aeruginosa were detected. Plasmid DNA analysis and pyocin typing were done.
  • Conclusion: Conclusion: This study investigated the correlation between fluoroquinolone (ciprofloxacin or levofloxacin) use and rates of fluoroquinolone resistance in Pseudomonas aeruginosa isolates from patients with nosocomial infection at a medical centre in Taiwan.
  • Keywords: infection, Pseudomonas, resistant, isolate, medical