Introduction: All organs of the potato plant contain two glyco alkaloids, alpha-solanine and alpha-chaconine, which are known as solanine poison. The permissible amount of solanine is 200 mg per wet weight of potato. This poison, which has pesticidal properties, causes the death of plant pests and acts as a natural defense mechanism for plants and is associated with plant resistance against Colorado potato beetle and potato leaf eater. Consuming a small amount of solanine and its derivatives initially causes pain and nervous problems such as diarrhea and vomiting, confusion, headache and itching. Consuming it in large quantities is dangerous for animals and humans and causes inflammation of the stomach and intestines and even death. Also, other risks of solanine are infertility, skin inflammation, hallucinations, fever and paralysis. These symptoms usually appear 8 to 12 hours after consumption, but in some cases, symptoms may appear quickly and after a few minutes after consuming high amounts of solanine. . Light, heat, germination and mechanical impact can increase this toxin, but humidity decreases its amount. The taste of this poison is characterized by burning mouth and throat.It has been said that the amount of solanine poison does not change much as a result of cooking and it is amount remains constant even up to 95%. this poison remains unchanged by frying in oil at 180 degrees Celsius,and if the same oil is used several times,the poison mey enter other foods. Therefore,the used oil should not be reused.In order to keep the level of glycoalkaloids in the potatoes low,keeping them in the light,in plastic bags and at a temperature of 7 degrees Celsius seems to be effective. Research has shown that the flavonoid in the mahor flower can be used yo treat complications caused by solanine poisoning. "Verbascum t hupsus" known as "Mullin" is a plant belonging to the monkey flower family and one of the med,icinal plants that is known in different regions as rabbit grass,rabbit flower, Mahor flowerand Mahor grass. This plant has been used since ancient times in traditional medicine to treat colds,angina and bronchitis,nervous disorders, anxiety,heart rhythm disorders and stomach discomfort as well as joint pain. This plant is also used to treat skin injuries. The anti-inflammatory effect of this plant is due to the presence of compounds such as flavonoids, saponins and ribascoside compounds. Flavonoids are various compounds that occur naturally in many fruits and vegetables. They are also in herbal products such as tea. . Flavonoids are rich in antioxidant activity and can help the body eliminate daily toxins, and in addition to antioxidant and anti-inflammatory activity, they are related to skin protection, brain function, blood sugar regulation, and blood pressure. . Due to its anti-inflammatory and antioxidant properties, this flower can be used to treat the effects of solanine poison.
Methods: In this research, plant extraction is done by a rotary evaporator . Then, in order to identify the compounds and also to separate them, a high performance liquid chromatography device "HPLC" will be used. Then by adding Oserin cream, our therapeutic ointment will be made. The ointment made is tested on mice poisoned with solanine poison found in potatoes, and it is hoped that this research will be successful.
Results: Considering the antioxidant properties of the flavonoid found in Mahor flower, we can hope that the ointment obtained from the extract of this plant will be useful in treating the effects of solanine poison.
Conclusion: This project is still an idea and has not reached the implementation stage, but we hope that the ointment made with the extract of the Mahor plant with antioxidant and anti-inflammatory properties will be effective in improving the complications caused by the solanine poison found in potatoes.