Introduction: Infectious diseases are one of the major causes of mortality rates in the world. The onset of methicillin-resistant Staphylococcus aureus (MRSA) has become a global concern in public health due to antibiotic resistance. The use of drug delivery systems is an effective way to rise drug stability and decrease antibiotic use. Nanofibers are versatile materials with numerous applications, from drug delivery to antibacterial carriers
Methods: Electrospinning is a versatile method to make micro- nano fibers by ejecting polymer solutions through a syring which could be coaxial or simple , under a high voltage.
Results: In this review, we focus on emphasizing challenges in treatments and drug delivery, especially antibiotics with nanofibers. Additionally, we provide an overview of current studies into the development of improved Methicin delivery systems using electrospun nanofibrous membranes for biomedical and tissue engineering applications.
Conclusion: There are different types of nanofibers based on the method of preparation, such as core-shell, hollow, porous, and non-porous nanofibers. One of the main applications of nanofibers is using them as carriers for the delivery and release of antibiotics in a particular time and space.
Keywords: Methicillin-resistant Staphylococcus aureus
Advanced drug delivery
Drug resistance
Nanofibres