Introduction: Microorganisms residing both on the surfaces and within the human body exert a profound influence on various physiological processes. Among these microbial ecosystems, the gut microbiome stands as the largest and most pivotal. Calcium disorders represent a significant health concern across numerous diseases, with conditions like chronic renal insufficiency leading to secondary hyperparathyroidism, a consequence of disrupted calcium homeostasis. Furthermore, disturbances in calcium regulation have been linked to aberrations in liver lipid metabolism via the calmodulator pathway, potentially culminating in conditions such as cirrhosis. Presently, a burgeoning body of evidence underscores the role of probiotics in augmenting calcium absorption.
Methods: reviewal
Results: This article provides a comprehensive overview of the intricate relationship between gut microbiota and calcium balance, encompassing key facets such as the impact of short-chain fatty acids, estrogen, immune factors, and vitamin D on calcium equilibrium. Additionally, it delves into the interface between gut microbiota, calcitonin, and bone metabolism, shedding light on the immunomodulatory effects of gut microbiota in the context of calcium balance. Furthermore, it explores the interplay between gut microbiota, vitamin D, and calcium absorption, as well as their influence on liver function and serum calcium levels.
Conclusion: Microorganisms residing both on the surfaces and within the human body exert a profound influence on various physiological processes. Among these microbial ecosystems, the gut microbiome stands as the largest and most pivotal. Calcium disorders represent a significant health concern across numerous diseases, with conditions like chronic renal insufficiency leading to secondary hyperparathyroidism, a consequence of disrupted calcium homeostasis. Furthermore, disturbances in calcium regulation have been linked to aberrations in liver lipid metabolism via the calmodulator pathway, potentially culminating in conditions such as cirrhosis. Presently, a burgeoning body of evidence underscores the role of probiotics in augmenting calcium absorption.
Keywords: Gut Microbiota, Calcium Balance, calcium absorption