• A COMPARISON BETWEEN LABLOTARY FERTILIZATION AND EGG DONATION: ASSISSTEND REPRODUCTIVES TECHNIQUE IN WOMEN WHTH ENDOMETRIOSIS
  • Reyhane Bahrami,1,*
    1. MSc in midwifery, School of Nursing and Midwifery, Isfahan University of Medical Sciences, Isfahan, Iran


  • Introduction: Endometriosis distorts pelvic function and anatomy through adhesions which could be associated with disorders in ovulation, fertilization and implantation in women with this problem. Recent advances in assisted reproductive techniques including artificial insemination and egg donation have increased the likelihood of childbearing for women with endometriosis who wish to have children. The present study was conducted to compare between laboratory fertilization and egg donation in women with endometriosis.
  • Methods: Methods: This systematic review was performed in Medline, EMBASE, Cochrane library, Science direct and Springer databases to find relevant articles. Search terms included lab oratory insemination, egg donation and endometriosis. Cohort studies (prospective and retrospective , case-control and case report studies assessing the results of egg donation and laboratory fertilization techniques in infertility among women with endometriosis were included. Out of52 papers identified through initial search, 40 relevant studies were selected from which, 19 paper s were included in this systematic review.
  • Results: Results: As compared to egg donation, rate of fertility and implantation were lower in laboratory fertilization per each cycle of using this technique in women with endometriosis (after 3 course of treatment, 48% v 58%). A direct association was observed between age of egg donor, egg quality, number of transferred fetuses to the uterus with implantation and live birth pregnancies (p<0.05).
  • Conclusion: Conclusion :It seems that egg donation method could be among acceptable approaches in order for infertility treatment among women with endometriosis.
  • Keywords: Assisted reproductive techniques, laboratory fertilization, egg donation, endometriosis