Introduction: Stem cells derived from adipose tissue of adult mice have the ability to differentiate into nerve and glial cells.
The ability to differentiate these cells into all types of cells, especially nerve cells, has been proven in laboratory conditions. But
the examination of cells after the transplantation of these cells in animal models of the diseasehas shown that only the MS A
small percentage of cells transplanted to myelin-forming cells have developed as a result of using another supplement such as
astaxanthin.(astaxanthin)which can improve the results of cell transplantation seems necessary.
Methods: In this review article, we have used the experiments and results of other scientists to better understand the article. Therefore, this article is a complete review. stem cells were isolated from the adipose tissue of the groin area and the back of the rat kidney
After disassembly and inspectionmarkers, these cells for 72 hours in CD mediumand in the presence of a concentration of DMEM-F12
different types of astaxanthin)were cultivated Then at the end of reproduction and viability (10ng/ml), (5ng/ml), (1ng/ml)
cells using the methodwas evaluated and evaluated by MTT.
Results: The results showed that a high percentage of cells(Mouse adipose derived stem cells, MADSCs
markersAnd a low percentage of them expressed hematopoietic cell markers. In addition, the average survival percentage of
CD 44 and CD90 in cells treated with5 ng of astaxanthin increased significantly compared to other groups (P=0.04)
Conclusion: Astaxanthin is able to increase the survival and proliferation of cellsand this substance can be used in the treatment of MADSCs
Neurodegenerative diseases in diseaseUsed MS.