Kiana Mousavie,1Saman Hakimian,2,*
1. Bachelor student of Midwifery,Islamic Azad university of Sanandaj,Iran 2. B.sc student of Microbiology Islamic Azad Univercity centeral Tehran Branch,Iran,Tehran
Introduction: Pregnancy is a major physiological and psychological life event , but pregnancy does not safeguard women against depressive disorders. rates of depression in women are higher during the childbearing but women with some specific factors like: Genetic _Poor social support _ Unplanned pregnancy and…. Are more vulnerable to depression during pregnancy.
Methods: The biological changes also have a direct effect on mood state concentrations for example: female specific sex steroids would raised during pregnancy and modify parts of the brain involved in mood regulation , also decreasing the dose of serotonin and dopamine which are two important neurotransmitters related to happiness and motivational moods of human would lead to depressive mood and low behavior.
But what can we do for this disorder? In this case we are forced to choose a way between bad and worse. But, the main question is treating or not treating?
Now we are going to take a look at some negative and positive points of treating this disorder
Results: during pregnancy : unfortunately there are no risk _free decisions for pregnant women with a psychiatric disorder but untreated depression during pregnancy may have negative results such as : 1.risk of miscarriage 2. Baby weight loss after birth and…
On the other hand treating this disorder would first lead to clinical participations and this action that is a Interdisciplinary collaboration considered as the first line of treatment but antidepressant medication considered as the second line of treatment which includes many negative affects on fetus like: a significant increase in the risks for major congenital malformations and preterm birth beside this I should add that antidepressant medications are considered as teratogens It is probably due to the role of serotonin in determining the left-right axis.
Conclusion: This review describes best practices for the management of depression in pregnancy, and it provides suggestions for future research.
Keywords: depression-depression during pregnancy-antidepressant-teratogen