مقالات پذیرفته شده در هشتمین کنگره بین المللی زیست پزشکی
A review of the transplantation of human umbilical cord mesenchymal stem cells for the treatment of premature ovarian failure
A review of the transplantation of human umbilical cord mesenchymal stem cells for the treatment of premature ovarian failure
Maryam Mirzalou,1,*
1. Department of Nursing and Midwifery, School of medical Sciences, University of Azad Marand Branch, Marand, Iran.
Introduction: Premature ovarian failure (POF) is one of the problems and diseases for women's reproductive health, the frequency of which has increased in recent years. Premature ovarian failure is one of the main causes of female infertility, which is identified before the age of 40.
Methods: In this systematic review, to identify studies aimed at the effect of human umbilical cord mesenchymal stem cell transplantation for the treatment of premature ovarian, search in Science Direct, PubMed, and Google Scholar databases based on keywords Premature ovarian failure, stem cell, umbilical cord was done. After checking the title and abstract of the articles, irrelevant articles were removed. The full text of the articles was searched and the articles related to the topic were included in the study.
Results: The causes of POF are unknown in 90% of cases, but studies have shown that treatment with stem cells is an effective method for treating infertility. Several environmental factors such as viral infections, and smoking can cause infertility and POF, and smoking extensively changes ovarian function.
Conclusion: Premature ovarian failure strongly affects the mental and physical health of young women. Women with this disease usually use hormones to treat the symptoms of estrogen deficiency, which is not very effective. We should look for better alternatives to treat most diseases, where treatment with stem cells is more effective than other methods.