• Investigating the relationship between antimullerin hormone and ovarian response in infertile women after IVF
  • Khadijeh Afshoun,1 Mohammadreza Pourmohammad,2,* Parvin Torabzadeh,4
    1. Clinical Research Development Unit, Imam Reza Hospital, Mashhad University of Medical Sciences, Mashhad, Iran
    2. Department of Medical Parasitology, Faculty of Paramedicine, Ilam University of Medical Sciences, Ilam, Iran
    4. Department of Biology, Karaj Branch, Islamic Azad University, Karaj, Iran


  • Introduction: Anti-Müllerian hormone has a good correlation with the age of the woman, the number of antral follicles and the result of assisted reproductive technology. The present study was conducted with the aim of investigating the relationship between anti-Müllerian hormone levels and ovarian response and pregnancy outcomes in infertile women undergoing IVF treatment
  • Methods: This cross-sectional study (descriptive-analytical) was conducted in 2020-2022 on 80 infertile women treated with ART infertility treatment, referring to the infertility center of Razavi Hospital in Mashhad. Demographic information, FSH and AMH levels, the number of injected gonadotropin ampoules, the number of antral follicles and the number of embryos obtained were checked and recorded in the questionnaire. Also, pregnancy outcomes including abortion, fetal death, fetal malformation and birth were determined and recorded in the questionnaire. Data analysis was done using SPSS version 26 statistical software and chi-square tests, Fisher's exact test, one-way analysis of variance and Pearson correlation. A p value of less than 0.05 was considered significant
  • Results: There was a significant correlation between the level of antimullerin hormone with the number of HMG injected, the number of retrieved eggs, the number of total embryos, type A and B embryos in women with agonist IVF. The mean AMH was 2.66 ± 1.66 pmol/dL. The amount of this hormone in women with positive and negative ovarian response did not differ, but in pregnancy and pregnancy with positive outcome, there was a significant difference with the group of no appropriate ovarian response. The amount of AFC before treatment in the pregnancy and pregnancy groups with a positive outcome and the Ovarian Insufficiency did not have a significant difference.
  • Conclusion: Determination of AMH levels is helpful in prescribing gonadotropin, predicting the number of antral follicles, retrieved eggs, and the number of embryos obtained, but the level of antimullerin hormone is not related to fertility outcome.
  • Keywords: Pregnancy outcome, gonadotropin, antimullerin hormone, IVF