An overview of the cause and trearment of gangrene

An overview of the cause and trearment of gangrene
Kimia Parsi,¹ Saman Hakimian,^2,*
1. Ms.c student Microbial Biotecnology of Tehran Islamic Azad University of Medical Sciences. Genetics Bachelor.
2. M.sc studet of pathogenic Microbes Islamic University Centeral Branch
Introduction: The clostridium perfrigens is an anaerobc,spore- forming, gram positive rod responsible for necrotizing (cells) tissue , then gangrene,bacterium in patients with cancer or gastrointestinal tract infection. The clostridium perfrigens species is associated with mushrooms and viruse eviroment such as soils, sewage, and food. However,it is also a compont of the gastroinstial microflora of sick and heathly humans and animals.
Methods: C. perfrigens type A is the major cause of traumatic gas gangrene. C. perfringens is linked with different systemic and enteric diseases in livestock and humans, such as gas gangrene, food poisoning, non-foodborne diarrhoea, and enterocolitis. We have three gangrene,such as : Dry Gangrene , Wet Gangrene and Gas Gangrene. Dry Gangeger is a gangrene in which oxygen does not reach it so the cell does not get infected. If there is a bacterial infection in the damaged tissue, gangarene is known as wet gangrene. Wet gangrene occure after a burn, severe frostbite or injury. Gas gangrene is usually caused by an infection with a bacterium called clostridium perfungus.
Results: Gas gangrene is a life-threatening condition that requires early treatment, including antibiotic prescription and amputation of human limbs.
Conclusion: People with diseases, high bloodpressure, obesity, smoking, hyperlipidemia and heart diseases are more exposed of gangrene.
Keywords: C. perfrigens. gangrene. Gas Gangrene. Wet Gangrene. Dry Gangrene. clostridium perfrigens.