• Approaches to traditional vaccines and the development of new vaccines
  • ramesh ranjbar,1,*
    1. 1- PhD student, Department of Genetics, Faculty of Basic Sciences, Shahrekord Islamic Azad University, Shahrekord, Iran.


  • Introduction: A vaccine is a biological product that specifically leads to acquired immunity against a pathogenic pathogen and prevents the disease in the face of the main pathogen in a person. Therefore, vaccines are an important tool for maintaining health in the global community.
  • Methods: this research is a review study and databases such as NCBI,PUBMED ,...have been used in this research.
  • Results: Traditional vaccines have been used against a wide range of pathogenic pathogens, both viral and bacterial, and have been successful. But these vaccines do not work and are not effective against pathogens that change rapidly in terms of genetic material and surface epitopes.
  • Conclusion: During the last decade, vaccines based on nucleic acids, viral vectors and biomaterials have shown promising results. In this study, an overview of traditional vaccines, mRNA-based vaccines, viral vector-based vaccines, and biomaterials has been discussed.
  • Keywords: Traditional vaccines, mRNA vaccines, viral vector vaccines, biomaterials, immune system