مقالات پذیرفته شده در هشتمین کنگره بین المللی زیست پزشکی
Investigating the phenolic properties of Cinnamomum verum extract
Investigating the phenolic properties of Cinnamomum verum extract
Zeynab Toluei,1,*Zahra Mirzakarimi,2
1. Department of Cell and Molecular Biology, Faculty of Chemistry, University of Kashan, Kashan, Iran
Introduction: Cinnamomum verum known as sweet cinnamon is native to Sri Lanka. The bark is widely used as a spice or seasoning in food and sweets. It is also used in making soap, dental products and perfumes. The main composition of its essential oil is sinaldehyde and eugenol. Sinaldehyde present in the plant plays a vital role in various metabolic pathways involved in hyperglycemia and metabolic syndrome. Also, cinnamon is effective in treating diabetes, high blood pressure, heart diseases, etc. Eugenol in cinnamon contains polyphenol compounds. Phenolic compounds have antioxidant properties and can improve oxidative stress symptoms such as malondialdehyde and superoxide desmutase levels.
Methods: In this study, we measured the polyphenol compounds in cinnamon extract. For this purpose, we first extracted the dry cinnamon bark with hot (Soxhlet) method. Next, 70% of the alcohol was removed from the extract by rotating. Then, Folin Ciocaltiou reagent was produced in the presence of phenolic compounds in 2% sodium carbonate alkaline solution and reduced distilled water and a blue color was produced in the solution. Color intensity was measured at 765 nm wavelength. The values of total phenolic content in the sample were determined according to the standard curve of gallic acid.
Results: The amount of phenol in cinnamon extract in this study is 120.58 gallic acid in μg.
Conclusion: The antioxidant capacity of natural products is attributed to the presence of phenolic compounds. Therefore, it can be said that cinnamon can deal with the increase in the level of oxidative stress factors and reverse its effects. These effects include reducing the level of malondialdehyde and improving the level of superoxide desmutase. This plant can be effective in treating diabetes and hyperglycemia etc. These people can be advised to use this substance in their diet.