• The effect of vitamin D supplementation on stroke
  • Shokouh Rahmati pour,1 Reza Bayat,2 Zahra Rezvani,3,*
    1. Department of cell and molecular biology, Faculty of chemistry, University of Kashan, Kashan, Iran
    2. Department of cell and molecular biology, Faculty of chemistry, University of Kashan, Kashan, Iran
    3. Department of cell and molecular biology, Faculty of chemistry, University of Kashan, Kashan, Iran


  • Introduction: Stroke is one of the main causes of death and disability. Vitamin D is a group of fat-soluble hormone precursors obtained from sunlight, food and nutritional supplements. The active form of vitamin D exerts its effect by binding to its receptor located in the nucleus of the target cells. Studies have shown that the lack of this vitamin can contribute to the worsening of diseases such as high blood pressure, diabetes, heart failure and stroke.
  • Methods: In this study, the effect and two-way relationship between stroke and vitamin D were studied, which were extracted and used from reliable information sources such as Google Scholar, Pambed and Science Direct.
  • Results: Evidence and studies have shown that there is a relationship between low levels of vitamin D in the blood and cognitive disorders in stroke, and the lower the level of this vitamin, the greater the extent of stroke in patients. It should be noted that stroke itself predisposes to more vitamin D deficiency and as a result the occurrence of diseases related to vitamin D deficiency such as repeated strokes and cardiovascular diseases.
  • Conclusion: According to the findings, using vitamin D supplements in the diet is a practical and low-cost way to help prevent many diseases, including stroke. The active form of vitamin D reduces stroke and reduces post-stroke effects.
  • Keywords: Stroke, vitamin D, body physiology, diet