مقالات پذیرفته شده در هشتمین کنگره بین المللی زیست پزشکی
Review and applications of Borage oil in specialized skin and hair products
Review and applications of Borage oil in specialized skin and hair products
Hamid Reza Ahmadi Ashtiani,1,*Maryam Kaveh Bakhshayesh,2Mohammad Esfandiyari,3
1. Department of Basic Sciences, Faculty of Pharmacy, Pharmaceutical Sciences Branch, Islamic Azad University (IAUPS), Tehran, IR Iran 2. Research and Development Department of Vesta Pharma Company 3. Research and Development Department of Vesta Pharma Company
Introduction: The extract of Borage, a native plant of Iran and distributed in the northern regions from Golestan to Ardabil and Qazvin province in the slopes of the Alborz mountain range, especially in the towns of Rudsar in the Ashkorat region, Kandavan, Chalus, and Hiran heights between Ardabil and Astara. It has been widely used in Iranian pharmaceuticals for a long time. In recent years, the oil extracted from this plant has been significantly used in skin and hair products. Following the use of the oil of this plant at the international level by Vesta Pharma Company, this article has investigated the effects, mechanism of action, available components, and scope of use in skin and hair products.
Methods: This study investigated valid scientific articles indexed in PubMed, Google Scholar, Science Direct, SID, and ISI databases using Persian keywords of medicinal plants, Borage, and keywords Borage Oil, Oils in Cosmetics, and Borage Oil in Skin and Hair.
Results: In this study, the main chemical compounds of Borage plant oil include gamma-linolenic acid, linoleic acid, oleic acid, palmitic acid, stearic acid, eicosenoic acid, erucic acid, flavonoids, saponins, terpenoids, rosmarinic acid, sterols, and tocopherol. It has the properties of improving skin barrier function, increasing collagen production, increasing elasticity, reducing infection, promoting wound healing, hydrating and moisturizing, softening, Promoting the production of anti-inflammatory eicosanoids, regulating cytokine production, improving eczema and seborrheic dermatitis, reducing oxidative stress, protecting DNA by modulating oxidative genetic damage and increasing and stimulating hair growth.
Conclusion: Borage is one of Iran's native plants, which has potential and actual medicinal, biological, and pharmacological properties. It therefore has a lot of application potential in the field of cosmetics and hygiene for use in products such as (moisturizers, lotions, cleansers, emollients, softeners, masks, anti-dandruff, and hair care products) and in the field of pharmaceuticals with applications in helping to treat skin and hair diseases.