• The effect of endurance training and ketosis on brain lactate with magnetic resonance spectroscopy in people with Verne hypertrophy
  • Zohre mohebbi kharati,1,* Shahin riyahi malayeri*,2 Maryam Rahamni,3
    1. Department of Sports Sciences, Tehran East Branch, Islamic Azad University, Tehran, Iran
    2. Associate Professor, Department of Sports Sciences, Tehran East Branch, Islamic Azad University, Tehran, Iran
    3. Department of Biology, East Tehran Branch, Islamic Azad University, Tehran, Iran


  • Introduction: Obesity is a growing global health problem, the prevalence of which is increasing in children and adults. More than 1.4 billion adults are overweight and another 500 million adults worldwide are classified as obese. Studying obesity is important because it is associated with an increased risk of developing a number of medical conditions. Overweight and obesity cause many diseases such as high blood pressure, diabetes, malnutrition, metabolic syndrome, inflammation, and neurological problems. It also increases the risk of cognitive decline and even the diagnosis of dementia in life. These findings are of considerable concern, as it is well documented that even the healthiest adults show age-related declines in basic cognitive operations, including processing speed, working memory, reasoning, and episodic memory. The effects of obesity are most prominent in brain aging. in old age and also this situation causes a further decrease in cognition.
  • Methods: Investigating the effect of endurance training and ketosis on brain lactate with magnetic resonance spectroscopy in people with hypervolemia Investigating the effect of endurance training and ketosis on weight in people with obesity Investigating the effect of endurance training and ketosis on fat percentage in people with excess fat
  • Results: A course of endurance training and ketosis has a significant effect on brain lactate by magnetic resonance spectroscopy in people with Verne's excess. A period of endurance training and ketosis has a significant effect on weight in people with overweight. A period of endurance training and ketosis has a significant effect on the percentage of fat in people with excess fat.
  • Conclusion: Pathological changes associated with obesity alter the uniformity of brain white matter neural networks, as demonstrated by diffusion tensor imaging (DTI). Increased mean diffusion (MD) and decreased fractional anisotropy (FA) in DTI observed in obese subjects may be due to degeneration of neural structures. This study aimed to investigate the effect of high-intensity interval training and ketogenic diet on brain aging in obese and overweight adults using DTI.
  • Keywords: endurance training, ketosis, Verne hypertrophy, magnetic resonance spectroscopy