Introduction: Angiogenesis which is associated with the production of new vessels, is an active and complex factor that occurs in pathological and physiological events. This research was conducted with the aim of investigating the effect of microcapsules containing the essential oil of mountain white coriander plant on the angiogenesis of the chorioallantoic membrane of chick embryos
Methods: In this study, fertilized eggs of the Ras breed were placed in 4 experimental groups, including a control group and 3 groups receiving drugs with doses of 100, 200, and 400 μg/ml. On the first day, the eggs were placed in the device and On the second day, a window was created on the eggs. On the 8th day, microcapsules containing Coriander essential oil with different doses were injected on the chorioallantoic membrane in the window area, and on the twelfth day, the chorioallantoic membrane was photographed by a stereomicroscope.
Results: The results show that by increasing the concentration of microcapsules containing white mountain coriander essential oil, we have a significant decrease in angiogenesis, so the microcapsule containing white mountain coriander essential oil has an anti-angiogenic effect, which significantly reduces the number and length of blood vessels
Conclusion: The microcapsule containing the essential oil of mountain white coriander plant reduces the number of vessels in the chorioallantoic membrane of chick embryos.