• A review of the effects of probiotics on metabolic syndrome
  • Marziyeh Mirzalou,1,* Mahdiyeh Mirzalou,2
    1. Department of Biological sciences and technologies, School of Medical Sciences., University of Azad marand Branch., marand, Iran
    2. Department of Biological sciences and technologies, School of Medical Sciences., University of Azad marand Branch., marand, Iran


  • Introduction: Obesity is increasing all over the world, which is associated with the development of metabolic syndrome (Mets) and can lead to a series of cardiovascular risk factors and metabolic diseases.
  • Methods: To identify studies aimed at the effect of probiotics on metabolic syndrome, this systematic review was conducted in Science Direct, Google Scholar, and PubMed databases based on the keywords Probiotics, Metabolic syndrome, and Obesity. After reviewing the summary of the articles and checking the title, the irrelevant articles were removed. The full text of the articles was searched and the articles related to the topic were included in the study.
  • Results: Changing the composition of the gastrointestinal tract microbiota can contribute to insulin resistance associated with obesity. In addition, consuming probiotics in MetS patients improves body mass index, blood pressure, and glucose metabolism. Also, probiotics positively affect the adhesion of soluble vascular cells.
  • Conclusion: Probiotics can be used as an adjuvant treatment to improve some clinical features of metabolic syndrome and inflammatory biomarkers. Also, from a clinical point of view, cardiovascular risk may be different in women than in men with this syndrome.
  • Keywords: Probiotics, Metabolic syndrome, Obesity