Fatemeh Tavangar,1Saman Hakimian,2,*
1. M.sc student of Islamic Azad Pathogenic Microbes Neishabur Branch University 2. M.sc student of Pathogenic Microbes Islamic Azad University Central Tehran Branch
Introduction: Irritable bowel syndrome (IBS) is a common digestive disorder in the world and was once known as a psychosomatic disease, which today has progressed a lot and causes changes in the number and type of intestinal microbiota and increases the activity of the immune system. Intestinal microbiota are considered as an essential organ.
The intestinal microbiota is closely related to (IBS). And the composition of the intestinal microbiota in healthy people is different from that of people with IBS. In general, the symbiotic relationship between the intestinal microbiota and the host with small changes causes IBD diseases. CD) and (UC). And according to the experiments, the change in intestinal microbiota is effective in causing colon cancer.
In addition to these Fungi, viruses, archaebacteria are observed in the samples.
Irritable bowel syndrome (IBS) disease affects the quality of human life and causes economic and social damage to life. And health care has a very important effect because these diseases cause an increase in mortality.
Therefore, according to the wide connection of pathophysiological mechanisms (RE) and (IBS), they have a relationship with depression, anxiety and stress.
Changes in the intestinal microbiota cause disturbances in the brain axis and autonomic nervous system, increase visceral sensitivity, and changes in digestive neuropeptides and hormones.
In addition to diet, characteristics such as age, gender, race, geographical environment, and the number and type of intestinal microbiota have an effect on causing the disease.
The symptoms of this disease (IBS) are mostly diarrhea or constipation, abdominal pain, weight loss, visceral sensitivities, nerve dysfunction, intestinal ulcers, excessive gas production, and difficulty in defecation.
IBS diagnosis criteria:
1.IBS_D diarrhea
IBS_C is constipation 2.
IBS_M includes both in a mixed form 3.
Treatments today are biological, non-biological and nutritional.
Antibiotics, probiotics, prebiotics, synbiotics and fecal microbiota transplantation are used for treatment, the last one being known as an excellent strategy for treatment.
Identification of intestinal microbiota and factors affecting them
Diagnosing the relationship between intestinal microbiota and irritable bowel syndrome (IBS)
Diagnosis along with effective treatment and reduction of disease progression (IBS)
Methods: This study is in the field of recognition, prevention and treatment of factors affecting intestinal microbiota and irritable bowel syndrome.
And for this study, Google Scholar database was used.
Results: The relationship between excessive growth of intestinal bacteria and intestinal microbiota is direct. Using articles, it was found that factors such as diet, gender, age, geographical environment, and any life habits (infectious gastrointestinal disease and radiotherapy) can affect changes in intestinal microbiota. It is effective and provides the basis for the disease (IBS).
Conclusion: Understanding the activity and interaction of the host with the gut microbiota helps in the diagnosis and treatment of IBS, which is one of the most common gastrointestinal disorders.