Combined hair stem cells transplantation and hair pulled out from root causes regrow hair
Combined hair stem cells transplantation and hair pulled out from root causes regrow hair
Samira Malekzadeh,1,*
1. Department of Biology, Shiraz Branch, Islamic Azad University, Shiraz, Iran
Introduction: Stem cells could treat hair and skin diseases like baldness and androgenetic alopecia of the scalp. Hair loss cause some personality problem such as, depression, decreased self-esteem, and decreased quality of life. Hair stem cells express Nestin and are able to differentiate to many cell types like neurons, keratinocytes, blood vessels, and cardiac muscles.
Methods: Hair stem cells originate from hair follicles in the bulge region. Based on FDA (Food and Drug Administration), some medications used for this condition like, minoxidil and finasteride. Also, stem cells are well treatment option for hair loss. Based on sources, Stem cells are different like, bone marrow, adipose, umbilical cord blood and hair follicles.
Results: Stem cells transplantation increased density and thickness without adverse effect or pain. But now we want to mention the simpler method of extracting the hair follicle and strengthening it by stem cells. In such a way that after pulling the hairs by applying the shaved head hair, under anesthesia. Then it is placed in an incubator in flask containing stem cells for several hours. After that, the strengthened hair follicles are transplanted.
Conclusion: This method is recommended for people with low hair bank or people who like to show thick hair. In addition to the high cost of the stem cell method, direct injection of stem cells increase concern in terms tumor development. On the other hand, transplanted of exosome and stem cell-derived conditioned medium (CM) is safer and more affordable.