Seroepidemiology of Toxoplasma Gondii in kidney transplant patients
Seroepidemiology of Toxoplasma Gondii in kidney transplant patients
Marzieh Latifi,1Elahe pourhosein,2Habib Rahban,3Tannaz Hajialireza Tehrani,4Sanaz Dehghani,5,*
1. Medical ethics and law research center, Shahid Beheshti University of Medical Sciences, Tehran, Iran. 2. Organ Procurement Unit Sina Hospital Tehran University of Medical Sciences Tehran Iran. 3. Creighton University School of Medicine, St. Joseph Hospital and Medical Center, Department of Cardiovascular Disease, Phoenix, Arizona. 4. Organ Procurement Unit Sina Hospital Tehran University of Medical Sciences Tehran Iran. 5. Organ Procurement Unit Sina Hospital Tehran University of Medical Sciences Tehran Iran.
Introduction: Opportunistic infection after transplantation is a serious problem. The most concerning of these infections are Toxoplasma gondii (T.gondii) and cytomegalovirus. The main goal of this study was to investigate the seroepidemiology of the T.gondii virus in kidney transplant patients at Sina Hospital in Tehran from 2017 to 2021.
Methods: 342 kidney transplant patients from Sina Hospital participated in this retrospective cross-sectional study by census method after obtaining consent. By referring to the medical records of kidney transplant patients and the transplant database of the transplantation unit of Sina Hospital, the desired data were collected and recorded in the prepared checklist. The data included demographic characteristics and cases of infectious tests related to kidney transplantation. The collected information was entered through the checklist in SPSS18 software.
Results: The age range of the investigated subjects was between 10 years and 73 years. A total of 125 patients in the study had kidney failure due to ERDS. The rate of exposure to T. gondii in kidney transplant patients was reported to be 54.2%, based on the regression test, gender did not predict any EBV.IgG, CMV.IgG and TOX.IgG.
Conclusion: Physicians should be aware of preventive measures and make an early diagnosis if there are compatible symptoms. All potential donors should be screened for anti-Toxoplasma IgM antibodies.