Azra Rabbani-Chadegani
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Abstracts, [Author]
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Study of HER2 gene expression in AGS cell line after treatment of cells with Crocus sativus (Iranian Saffron) extract
Cancer; Prevention, Diagnosis and TreatmentThe study of HER-2 gene in cancers, especially gastric cancer, is of great importance. This gene, has been shown to inc...Read more
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The effects of preconditioning mesanchymal stem cells with hydrogen peroxide and serum deprivation on cell viability and apoptosis.
Stem cell and Medical ApplicationsIt is known that application of mesenchymal stem cells is an effective treatment in many diseases. Despite of cell thera...Read more
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Recent study about Genetics of Human Obesity
Medical GeneticsObesity has become a global epidemic and contributes to the increasing burden of type 2 diabetes, cardiovascular disease...Read more
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A brief review of regenerative dentistry
Stem cell and Medical ApplicationsTissue regeneration idea has been formed by stem cells identifying and tissue engineering techniques. Stem cells can be ...Read more
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Study of PAX5 gene expression in patients with gastric cancer
Cancer; Prevention, Diagnosis and TreatmentGastric cancer is one of the biggest health problems in the world. Due to the lack of many carcinogenic biomarkers and t...Read more
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Evaluating the genetic variations of ARPT1 gene in infertile men with abnormality in sperm head morphology referring to Royan institute.
Medical GeneticsThe evaluation of human sperm morphology is a controversial aspect of the semen analysis for the determination of maleâ€...Read more
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The effects of specific expression of Apoptin under control of PSES and PSA promoter on apoptosis of LNCaP cells
Cancer; Prevention, Diagnosis and TreatmentApoptotic effects of viral protein Apoptin has been demonstrated in numerous studies. However, its tumor specificity has...Read more
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Investigating the Epidemiology of Concussed Patients, Hospitalized in Khatam al-Anbyia and Ali ibn Abi Talib Hospitals in Years 95-96
Microbiology and Infectious DiseasesFrom the point of view of frequency and importance, Brain vascularaccidents take the first place among all the neural di...Read more
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Rosmarinic acid, a Anti-glycation agent, inhibits protein glycation in vitro
Metabolism and Metabolic DiseasesDiabetes mellitus is one of the most non-communicable diseases and is the fifth leading causes of death in most of the d...Read more
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Development of an Antagonistic TGF-β by Directed Blocking of its TβRI Binding Site to Inhibition TGF-β Signaling
Cancer; Prevention, Diagnosis and TreatmentTransforming growth factors beta (TGF-βs) play vital roles in regulating cell growth, differentiation and inflammation....Read more
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Genetic variations of Cholesteryl ester transfer protein and diet interactions in relation to lipid profiles and coronary heart disease: A systematic review
Nutrition and HealthThe number of investigations on diet–genotype interactions in the prevention or treatment of dyslipidemia have increas...Read more
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Efficacy of Bone Marrow Mesenchymal Stem Cells and an Amniotic Membrane on the Number of Mast Cells and Degranulation in Random Skin Flaps in Rats
Stem cell and Medical ApplicationsSkin flap procedures are usually used in plastic surgery. Failing can follow, lead to the necrosis of the flap. Therefor...Read more
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SNP genotyping within INS, INSR, TCF7L2 and PPR- y genes associated with type 2 diabetes in India
Medical GeneticsA pilot population-based study was carried out to evaluate linkage between singlenucleotide polymorphisms within the kn...Read more
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Evaluation and comparison of digestion in two traditional and contemporary medicine schools And its effect on the treatment of diseases
Nutrition and HealthProper nutrition is one of the principles of "preserving health" in traditional and contemporary medicine. Wha...Read more
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Silencing of TIM-3 expression by miR-326 affects apoptosis and proliferation of human HL-60 leukemia cell line
Cancer; Prevention, Diagnosis and TreatmentLeukemia Stem Cells (LSCs) are the main reason for drug-resistance and disease relapse in Acute Myeloid Leukemia (AML). ...Read more
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Protective effect of silymarin on plasma membrane and DNA integrity of human sperm treated with cadmium chloride
Women and Reproductive HealthCadmium, as an environmental pollutant, exerts its destructive effects on male reproductive system and sperm by inducing...Read more
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the effect of crocin on forgetfulness caused by cholestasis in male rats(behavioral , biochemical and genetical )
Metabolism and Metabolic Diseasescholestasis is a condition in which the bile ducts that carry bile from the liver to the intestine to dispose, is blocke...Read more
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Crispr/cas9 a New Approach to Genome Engineering
Medical GeneticsIn 1987, scientists found an acquired immune system in E.coli genome, included series of short repetitive interspaced pa...Read more
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rDKK1 production and purification as an antigen
Cancer; Prevention, Diagnosis and TreatmentA critical goal in prevention and control of cancer is early detection of cancer. It is suggested that the Dickkopf1 (DK...Read more
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study of mesenchymal stem cell differentiation to chondrocyte on electrospun nanofibrous polyvinyl alcohol alginate sulfat blend
Stem cell and Medical ApplicationsCartilage tissue engineering is used as a potential solution for replacing or repairing damaged tissue. In this method, ...Read more
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Isolation and identification of probiotic bacteria from human milk
Microbiology and Infectious DiseasesBackground: Breast milk is the best nutritional supplement during the first few months of the baby's life. It contains v...Read more
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New mutation in hotspit region of APC gene in FAP patient in Guilan province
Medical GeneticsFamilial adenomatous polyposis (FAP) is a colorectal cancer predisposition syndrome characterized by the presence of hun...Read more
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The effects of anticancer of 7-hydroxycoumarine on the colon cancer cell line (HT29) and the normal mouse fibroblast cells (L929)
Cancer; Prevention, Diagnosis and TreatmentColorectal cancer it is a lethal and common cancer. due to the development of drug resistance to chemical drugs, the ne...Read more
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Fast detection of Pseudomonas aeruginosa keratitis by Polymerase Chain Reaction (PCR)
Microbiology and Infectious DiseasesPseudomonas aeruginosa is an opportunistic pathogen that has different virulence factors. This organism is commonly foun...Read more
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Design and evaluation of a colorimetric method for rapid determination of minimal inhibitory concentration of the bacteria belonging to Enterobacteriace
Microbiology and Infectious DiseasesIsolation of antibiotic resistant pathogenic bacteria in clinic may pose the serious problems. So a rapid method capabl...Read more
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Pattern of efflux pump genes in imipenem resistant Acinetobacter isolates
Microbiology and Infectious DiseasesAcinetobacter species are opportunistic pathogens and responsible for various types of nosocomial infections. They are i...Read more
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Computer aide discrimination of the ovarian lesions by CT scan images
Cancer; Prevention, Diagnosis and TreatmentTo explore diagnostic potential of computerizing texture analysis (TA) methods in discrimination of the normal, benign...Read more
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Anemia, a common disease in hemodialysis patients
Metabolism and Metabolic DiseasesChronic renal failure stage of renal insufficiency it is said that all the no longer able to repel and not toxic waste a...Read more
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Evaluation of cytotoxicity effects and NM23 gene expression against breast cancer T47D cells treated by Zn oxide nanoparticles( ZnNPs)
Stem cell and Medical ApplicationsBreast cancer is the second leading cause of cancer related death worldwide among women. Many investigations have confir...Read more
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Client's Attitude Towards legal and Ethical Aspects of Sperm Donation in a Health Center of Tehran
Women and Reproductive HealthSperm donation is one of the technologies associated with infertility treatment. Some couples don't have any child due t...Read more
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Operational study of plastination as an alternate method for dissection
Nano-Biotech MedicalSince, two-thirds of the approved Zoology Laboratory syllables, defined by the Ministry of Science, Research and Technol...Read more
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Diagnosis of Cytomegalovirus in Sinusitis by Molecular method
Microbiology and Infectious DiseasesCytomegalovirus is one of the important viruses that can cause a wide range of diseases in humans. Sinusitis is a common...Read more
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Synergistic Antibacterial Activity of Zinc Oxide Nanoparticles with Cuminum cyminum L. Essential Oil against the Food-Borne Pathogens Salmonella enterica
Nano-Biotech MedicalOne of the ways to control of pathogenic microorganisms in foods is to use preservatives and antimicrobial agents. Diffe...Read more
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Evaluation of the level of some of the Trace elements in the sprayer workers
Metabolism and Metabolic DiseasesPesticides and toxins have deleterious effects on human health and can affect the biochemical factors of the body. There...Read more
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Preparation and optimization of chitosan nanoparticles containing vancomycin
Nano-Biotech MedicalRecently, some novel drug delivery systems were designed to control drug release. The using of polymeric nanoparticles a...Read more
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Eradication of Cancer Stem Cells through microRNAs: a conceptual view
Cancer; Prevention, Diagnosis and TreatmentmicroRNAs (miRNAs), as 19-24 nucleotides endogenous non-coding RNAs, are involved in the most cellular processes playing...Read more
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Prevalence of beta-lactam resistant isolates of Enterobacteriaceae in clinical specimens
Microbiology and Infectious DiseasesBackground: The emergence of extended-spectrum beta-lactamase (ESBL) producing isolates of Enterobacteriaceae has impor...Read more
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Investigation of C-582 A>G polymorphism at beta globin cluster gene in beta-thalassemia patients
Medical GeneticsThalassemia is the most prevalent monogenic disorder worldwide resulting from the inappropriate production of heme. pati...Read more
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Investigating the toxicity of PEGylated Gold Nanoparticles and red LED light on Ecoli bacteria
Nano-Biotech MedicalToday, the emergence and spread of antibiotic-resistant strains of bacteria have become a major challenge to public heal...Read more
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Frequency of TEM and SHV genes in the strains of Acinetobacter producing broad-spectrum isolated ß-lactamases from Zahedan patients by PCR method
Microbiology and Infectious DiseasesAcinetobacter baumannii is one of the most important factors in hospital infections, and its Colonization rate in hospit...Read more
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the role of genetics in diabetes and its complications
Medical GeneticsThe purposes of writing this article are the significant role of genetics in the onset of diabetes, hoping to be treated...Read more
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Study of MiRNA-873 expression in Ectopic pregnancy, Endometriosis and Ovarian cancer (review)
Medical GeneticsMicroRNAs are small non-coding RNA molecules that have functions in post-transcriptional regulation of gene expression. ...Read more
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Evaluation of H.pylori drug resistance to current cure in North-West of Iran
Microbiology and Infectious DiseasesAlmost half of the world population is infected with Helicobacter pylori, a major risk factor for chronic gastritis, pep...Read more
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Apoptotic and cytotoxic effect of the thiosemicarbazone complex with Zn2+ in K562 cell line
Cancer; Prevention, Diagnosis and TreatmentThiosemicarbazone family is organic compounds with antitumor, antibacterial and antiviral effects. In the present stud...Read more
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A Review Article on Treatment with Stem Cells: Complications and Problems
Stem cell and Medical ApplicationsNowadays, various methods of treatment with stem cells are developing fast while such treatments have different and some...Read more
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Assessment of the dietary intake of Vitamin D and Blood pressure in Elderlies with health care
Nutrition and HealthPopulation studies have demonstrated that there is an inverse association between dietary intake of vitamin D and incide...Read more
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Comparative study of Calendula officinalis and Matricaria chamomilla extracts on Cisplatin induced neuropathic pain
Cancer; Prevention, Diagnosis and TreatmentCisplatin is one the most important cancer chemotherapy agents that uses for two decades. Neuropathic pain induced by th...Read more
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The effects of nano-liposomes containing curcumin on the lung cancer cell line.
Nano-Biotech MedicalLung cancer is one of the most common and malignant cancer in both sexes. The prevalence and spread of cancer in iran an...Read more
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CLONING AND EXPRESSION OF an antibody fragment (scFv) against PcrV protein of Pseudomonas aeruginosa in fed-batch cultivation mode
Microbiology and Infectious DiseasesPseudomonas aeruginosa is a major cause of hospital-acquired infections, particularly in mechanically ventilated patient...Read more
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The effect of mouse recombinant resistin on blood- brain barrier permeability, MDA content and apoptosis in the early stages of focal cerebral ischemia in a stroke mouse model
Metabolism and Metabolic DiseasesThe aim of this study was to evaluate the dose-dependent effects of mouse recombinant resistin on blood-brain barrier(BB...Read more
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Interaction of Methotrexate on Stability and structure of Human Serum Albumin
Nano-Biotech MedicalHuman serum albumin(HSA) as the most abundant carrier protein in blood plasma has been widely studied. HSA is often used...Read more
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Omega-3 and its effects on colorectal cancer
Cancer; Prevention, Diagnosis and TreatmentCancer as the second leading cause of death has always been a threat to human life and due to its peculiar nature and la...Read more
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Improvement of Prognostic model for breast cancer recurrence by data mining methods
Cancer; Prevention, Diagnosis and TreatmentIn Iran, every year 10,000 people suffer from breast cancer, of which half of them are under the age of 50. The recurren...Read more
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Sugar-sweetened beverages increase cardiovascular risk in diabetic patients
Nutrition and HealthSugar sweetened beverages (SSBs) are any type of sugar-added drinks like soft drink, syrup, etc. SSBs consumption has in...Read more
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Easy and efficient purification of flagellin from salmonella typhimurium ATCC 14028 without necessity of ultracentrifugation
Microbiology and Infectious DiseasesGram negative bacteria's Flagellin has many applications in diagnosis, treatment and vaccines. fliC, the major protein o...Read more
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Cytotoxic evaluation of cumin essential oil on breast cancer cell line (MCF-7)
Cancer; Prevention, Diagnosis and TreatmentCancer can be considered as one of the genetic diseases that reduces the mortality rate in cancer cells in this disease....Read more
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Cloning and expression of recombinant Cecropin A in Nicotiana tabacum L. hairy roots and its antimicrobial properties
Microbiology and Infectious DiseasesCecropins are a group of antimicrobial peptides (AMP) derived from innate immune system of various multicellular organis...Read more
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Effect of Velcade in Combination with Nanocurcumin in Breast Cancer 4T1
Nano-Biotech Medical: It is well known that breast cancer has the highest incidence rates of about 30% of all types of cancer in women, and ...Read more
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Molecular markers in the diagnosis of lung cancer
Cancer; Prevention, Diagnosis and Treatmentlung cancer is the leading cause of cancer-related mortality, one of the main causes of mortality by 2010. There are sev...Read more
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Prognostic value of MSI status in colorectal cancer patients
Cancer; Prevention, Diagnosis and TreatmentMicrosatellite instability (MSI) causes hereditary non-polyposis colorectal cancer (HNPCC), and occurs in about 15 per c...Read more
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Hydroxyapatite-Gelatin-bone marrow stromal cells construct as an excellent bone graft in animal model
Stem cell and Medical ApplicationsBone healing of critical-sized defects are one of the most challenging orthopaedic problems. In the current study, the e...Read more
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Investigating the absorption of anti-cancer drugs on the surface of the boron nitride nano cage by the dense function theory
Nano-Biotech Medicalmagesterol is a drug used in the treatment of breast and endometrial cancer. Due to the unwanted side effects of this dr...Read more
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Molecular detection of factor 5 Leiden (G1691A) and its relation with TNF- α gene polymorphism in human abortion
Medical GeneticsAbortion is the most common of pregnancy complications. In the pathogenesis of abortion as a multifactorial disease, gen...Read more
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The effect of manual acupuncture on anthropometric parameters in obese and overweight patients
Nutrition and HealthObesity is a chronic disease which is on the increase. Treatments of obesity include diet therapy, exercise, behavior th...Read more
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Modeling of cancer drugs on the route JAK-STAT in cancer stem cells
Cancer; Prevention, Diagnosis and TreatmentAbstract JAK/STAT pathway is one of a handful of pleiotropic cascades used to transduce a multitude of signals for dev...Read more
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Evaluation of antioxidant activity and cytotoxicity of an ethanol extract of leaves, fruits and calyx of Physalis alkekengi on human lung cancer A549 cell line
Cancer; Prevention, Diagnosis and TreatmentLung cancer is the most common cancers and chemotherapy cancer treatment is one of the methods, but because of the lack ...Read more
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Optical, structural and antibacterial properties assessment of ZnO:Mn nanoparticles
Nano-Biotech Medicalwith the rapid development of human life, controlling the harmful impacts of microorganisms is essential. The current st...Read more
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Investigating the presence of chemical compounds in pineapple
Cancer; Prevention, Diagnosis and TreatmentPineapple is a member of the Ananasian family, it is a sub-tropical fruit. It has many chemical compounds that are impor...Read more
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Anthropometric Survey of Worker Population in Bandar-Abbas
Cancer; Prevention, Diagnosis and Treatment1. Background Anthropometry is the science of measurement of body characteristics such as reach, body segment length, ...Read more
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Apoptotic effect of anticancer drug Alimta on A549 calls is independent of HMGB1 release
Cancer; Prevention, Diagnosis and TreatmentLung cancer is the leading cause of cancer-related deaths worldwide. Alimta is a new-generation antifolate drug, approv...Read more
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The Role of Viral Proteins VP24 and VP35 in The Pathogenesis of The Ebola Virus
Microbiology and Infectious DiseasesThe Ebola virus is a member of the Filoviridae family, which is causing hemorrhagic and fatal fever to humans. Ebola is ...Read more
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The effect of curcumin, zinc and N-acetylcysteine on the MMP9 expression
Metabolism and Metabolic DiseasesCardiovascular diseases (CVD) are mostly prevalent in the general population.Matrix metalloprotease 9 (MMP9) is a matrix...Read more
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Evaluation of the HLA-B46 Allelic frequency in the patients with spondyloarthritis syndrome in zanjan province
Medical GeneticsSpondyloarthritis is a group of multi-systematic disorders that has been created by spinal features, peripheral jointsan...Read more
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Assessment of energy and water-soluble vitamins intake in the elderly under health care, Isfahan, Iran
Nutrition and HealthThe B vitamins are essential nutrients to maintain nutritionally healthy body. These water soluble vitamins are critical...Read more
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Association between the CYP2E1 polymorphisms and CML risk in Iranian population
Medical GeneticsPolymorphism in the genes encoding detoxification enzymes results in variability to metabolize carcinogens and cause int...Read more
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Effect of Zinc nanoparticle on p53 expression in K562 cell line by Real Time PCR
Medical GeneticsChronic myeloid leukemia is a cancer of blood which is identified by bcr/abl translocation. Imatinib is a tyrosine kinas...Read more
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The effect of ziziphora extract on the expression of the Claudin_1 gene in the AGS cell line
Cancer; Prevention, Diagnosis and TreatmentClaudins are the main structural and functional proteins of tight junctions in epithelial cells. The altered expression ...Read more
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Altered miR-335-5p and miR-124-3p expression in gastric cancer
Medical GeneticsGastric cancer (GC) is fourth most common cancer and third leading cause of cancer mortality worldwide. Considerable eff...Read more
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Identification of the gene involved in over-production of a novel lipopeptide in an over-expressed mutant of Pseudomonas gingeri
Microbiology and Infectious DiseasesLipopeptides as secondary metabolites, produced by Pseudomonads, can be used as biosurfactants and antimicrobial drugs i...Read more
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Interaction of an anti-cancer drug Crizotinib with serum albumin: A docking study
Cancer; Prevention, Diagnosis and TreatmentCancer treatment is one of the major challenges of medical science today. Among them, lung cancer is a common type of ca...Read more
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Microfluidic Nanocomplex-Based Localized Gene Delivery Platform for Bone Tissue Engineering.
Stem cell and Medical ApplicationsAnnually more than 2.2million bone graft procedures take place in worldwide. Biomaterials-based bone tissue engineering ...Read more
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Evaluation of nitrosative stress in sprayer workers
Metabolism and Metabolic DiseasesAgricultural pesticides have an important impact on human health and farmers are people who are more exposed to pesticid...Read more
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Constructing a Novel Hypoxia-Inducible Bidirectional shRNA Expression Vector for Simultaneous Genes Silencing in Colorectal Cancer Gene Therapy
Cancer; Prevention, Diagnosis and TreatmentBackground: RNA interference (RNAi) is an efficient genetic approach in gene-specific knockdown and gene therapy; howeve...Read more
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TYCSB culture media reliability for S. mutans isolation
Microbiology and Infectious DiseasesAlthough the clinical significance of dental caries is well recognized, the exact etiology of the condition is not under...Read more
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Matrix metalloprotease-9 (MMP-9) and premature myocardial infarction: A systematic review and meta-analysis
Medical GeneticsCurrent findings on the role of Matrix metalloproteases (MMPs) in cardiac remodelling and the outcome after acute premat...Read more
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Apoptotic Effect of Tamoxifen on Hepatocellular Carcinoma Hep G2 Cell Line
Cancer; Prevention, Diagnosis and TreatmentHepatocellular carcinoma (HCC) is the sixth most common cancer, and the third most common cause of cancer-related death...Read more
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Inflammatory markers, vitamin D status and FokI polymorphism of the VDR gene in overweight women
Nutrition and HealthThe present study aimed to evaluate the relationship between inflammatory markers, vitamin D status and FokI polymorphis...Read more
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Prevalence of Pediculus capitis among School Children in the Eastern Area of Ahvaz, Southwestern Iran
Microbiology and Infectious DiseasesHead lice are wingless, obligate ectoparasites of humans, which affect millions of children worldwide, especially those...Read more
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Mesenchymal stem cells enhance the metastasis of cervical cancer cell line, CaSki, in 3D cell culture system
Cancer; Prevention, Diagnosis and TreatmentMesenchymal stem cells, also known as mesenchymal stromal cells (MSCs), are attractive for repair and regeneration of ti...Read more
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Evaluation of Acholeplasma laidlawii in biologic products by PCR method
Microbiology and Infectious DiseasesContamination of biological products and cell cultures is one of the important problems in producing a good and safe pro...Read more
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Anti-cancer effect of redroot pigweed as weed plant species
Cancer; Prevention, Diagnosis and TreatmentLeukemia cancer is currently one of the major causes of cancer-related deaths among humans. Extracts of plants including...Read more
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Antioxidants as DNA protective compounds
Nutrition and HealthBased on the recent findings, antioxidants are some essential factors that can have major role on the health. The human...Read more
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Effect of hydroalcoholic leaf extract of Ziziphora tenuior L. on pain in male rats
Microbiology and Infectious DiseasesZiziphora tenuior is one of the traditional medicinal herbs; the main active chemical composition of this herb is an ing...Read more
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Effects of Rosmarinic acid on oxidative stress and total antioxidant capacity in vivo study
Metabolism and Metabolic DiseasesDiabetic disease is characterized by chronic hyperglycaemia. Numerous studies have shown that in diabetes mellitus, ther...Read more
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The nutritional benefits of Pistacia atlantica
Nutrition and HealthPistacia Atlantica Mutica is a genus of the family Anacardiaceae which consist of different parts such as fruit, leave a...Read more
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The study of Apolipoprotein E4 allele distribution in parents of Down's syndrome children as a risk factor in Iran
Medical GeneticsDown syndrome(DS) is the most common chromosomal abnormality.The most important factor in DS is increased maternal age s...Read more
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Examination of mutations in QRDRs in ParC, ParE genes Salmonella Clinical Examples of Zahedan Hospitals
Microbiology and Infectious DiseasesSalmonellosis is a major public health problem worldwide. Although most Salmonella infections result in mild self-limiti...Read more
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Drafting maggot therapy in personalized cancer therapy
Cancer; Prevention, Diagnosis and TreatmentIn some personalized cancer therapies the elimination of the tumor will be a result of the injection of flesh- eating ba...Read more
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Synthesis of pH-sensitive micelles based on F127-Dox conjugated for drug delivery to cancer cells
Nano-Biotech MedicalA variety of nano-systems constituted by polymer–drug conjugates have been designed to overcome its shortages on water...Read more
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Effect of Valproic Acid on Proliferation and Apoptosis of Colon Cancer HT 29 Cell Line
Cancer; Prevention, Diagnosis and TreatmentThe structure of chromatin is made up of DNA, histones, and non-histone proteins with the basic repeating unit, nucleoso...Read more
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evaluatin of expression of HIF-1alpha gene in various types of colon polyps
Medical GeneticsCancer in iran after cardiovascular diseases and accidents is the yhird leading cause of death. Research has shown that ...Read more
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The impact of the vaginal probiotic lactobacillus on the prevention and treatment of cervical cancer
Cancer; Prevention, Diagnosis and TreatmentToday, cervical cancer is the second most common cancer after breast cancer among women and it`s considered dangerous ...Read more
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Identification and Cloning of Plasposon Insertion Site in Four Mutants of Pseudomonas Gingeri Deficient in White Line Reaction
Microbiology and Infectious DiseasesAntibiotic resistance is an important concern in the world and also in Iran. Identifying new antimicrobial strategies to...Read more
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Evaluation of cytotoxicity of aqueous-ethanolic extract of pineapple on ovarian cancer cells (A2780 cell line)
Cancer; Prevention, Diagnosis and TreatmentToday, the global trend towards the use of herbal medicines for treating diseases has tended, while developed countries ...Read more
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Explaining Women's Views on Cervical Cancer: A Qualitative Study
Cancer; Prevention, Diagnosis and TreatmentCervical cancer is the second most common cancer in the world , Which, if detected and treated at early stages, is almo...Read more
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The Expression Profile of ERBB3 and Its Ligand NRG1 on Depressed Patients Investigation in Hormozgan
Medical GeneticsMajor depressive disorder (MDD), also known simply as depression, is a mental disorder characterized can negatively affe...Read more
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Investigation of A New Paclitaxel Nano Niosomal formulation and Biological Evaluation of Entrapped Paclitaxel on breast cancer cell line
Nano-Biotech MedicalRegarding that the breast adenocarcinoma is the most widespread disease among women, paclitaxel, an anti-cancer drug, co...Read more
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An Evaluation of Tissue Destruction Time in Phrenic Nerve after Death and Counting the Number of Nerve Fibers in C3, C4 and C5 Branches
Cancer; Prevention, Diagnosis and Treatmentمقدمه اعصاب ÙØ±Ù†ÛŒÚ© Ú†Ù¾ Ùˆ راست، Ù…ØØ±Ú© اصلی عضلة Ø¯ÛŒØ§ÙØ±Ø§Ú¯Ù… میباشند( .)5ای...Read more
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Comparison of in vitro survival of mononuclear cells derived from B-CLL patients with or without BAFF & APRILL cytokines
Cancer; Prevention, Diagnosis and TreatmentThis article studies the antiapototic effect of cytokines BAFF & APRIL on the survival of mononuclear cells derived ...Read more
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Detection of Hepcidin biomarker in plasma of patients with stomach tumor before and after treatment
Cancer; Prevention, Diagnosis and Treatment: cancer is a very important public health problem, which is the main cause of death inindustrialized countries and incr...Read more
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Genetic Diversity and Phylogenetic Analysis of the Iranian Leishmania Parasites Based on HSP70 Gene PCR-RFLP and Sequence Analysis
Microbiology and Infectious DiseasesDespite the broad distribution of leishmaniasis among Iranians and animals across the country, little is known about the...Read more
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Investigating th expression of E-cadherin gen among patients suffering from stomach cancer in West Azerbaijan province
Medical GeneticsGastritis Cancer is one of the general death causes of cancer all over the world. According to the results of the resea...Read more
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The Effect of Vitamin D on Diabetes Mellitus: A Systematic Review
Metabolism and Metabolic Diseases: Diabetes Mellitus is a common metabolic and non-infectious disorder that affects around 346 million people worldwide w...Read more
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Ginseng For Improving The Quality Of Life In People With Cancer and Fatigue- A Systematic Review
Cancer; Prevention, Diagnosis and TreatmentBackground and purpose: An important issue in cancer health care is the improvement in quality of life (QoL). Physicians...Read more
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Hepatoprotective effects of magnesium sulfate on pentylenetetrazol-induced seizures in male Wistar rats
Nutrition and HealthMagnesium is the second most abundant cation (after potassium) in the cell and plays an important role in various biolog...Read more
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Anticancer effect of Quercus infectoria aqueous leaf extracts against colon cancer HT29 cell line
Cancer; Prevention, Diagnosis and TreatmentIn traditional medicine and previous studies, Quercus infectoria plants are a well-known and have been suggested as a ca...Read more
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T cell engineering for cancer imenuterapy
Cancer; Prevention, Diagnosis and TreatmentWith regard to the prevalence of cancer in the world, treatment have become important. One of the methods is to stimula...Read more
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Characterization of a carboxypeptidase inhibitor peptide isolated from Iranian scorpion venom glands cDNA library: a good candidate for cancer therapy
Cancer; Prevention, Diagnosis and TreatmentFinding a safe strategy for targeting tumor cells without affecting normal cells is one of the goals of cancer treatment...Read more
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Association between mtDNA D-Loop Mutation and secondary lung cancer
Cancer; Prevention, Diagnosis and TreatmentLung cancer is one of the leading cause of cancer death in the world. The aim of this study was to determine deletions ...Read more
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The Study of the Frequency of Antibiotic Usage as an Important Factor in Appearing Antibiotic Resistance in All of the Units in Namazi Hospital
Microbiology and Infectious DiseasesAs the unusual increase in using antibiotics has been suggested as an indicative factor in appearing antibiotic resistan...Read more
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Computational analysis and design of crRNA for post transcriptional regulation of metastamiR-10b and metastamiR-126 by CRISPR-C2C2 technique.
Medical GeneticsOne of the important causes of death in cancer patients is metastasis. Recently have been shown that specific group of m...Read more
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Biological and Molecular Diversity in Telomerase: Characteristics of hTERT in Human, Vertebrates and Yeast
Medical GeneticshTERT (human telomerase reverse transcriptase) is the catalytic subunit of telomerase enzyme, and is essential for its ...Read more
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Assessment of Tuberculous arthritis using molecular technique
Microbiology and Infectious DiseasesBacterial arthritis is one of the arthritis diseases known that can rapidly cause joint damage. Among the bacteria caus...Read more
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The effects of sodium butyrate on the expression of HDAC8 gene in HT-29 colorectal cancer cell line
Cancer; Prevention, Diagnosis and TreatmentSodium butyrate (NaB) is a potent growth inhibitor and initiates cell differentiation for many cell types in vitro. In t...Read more
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Performing PGD combined with HLA typing on more than 100 blastomeres
Medical GeneticsPreimplantation genetic diagnosis (PGD) is an option for carrier couples who want to assure their child’s health regar...Read more
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Biosynthesis of Gold nanoparticles by Areca palm fruit extract
Nano-Biotech MedicalTargeted drug delivery by Gold nano particles (AuNPs) is a new era in pharmaceutical research; i.e. curing tumoral cance...Read more
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Optimization of epi-drug combination against Glioblastoma multiform cell line (U251) using Response Surface Methodology
Cancer; Prevention, Diagnosis and TreatmentGlioblastoma multiform (GBM) is the most common and aggressive form of primary brain cancer and has a dismal prognosis, ...Read more
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Study of DNA methylation pattern in sf-1 gene promoter region in endometriosis tissue samples of women in north west of Iran
Medical GeneticsEndometriosis is an estrogen-dependent inflammatory disease. Its defining feature is the presence of endometrium-like ti...Read more
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Investigating the Verification of the Personnel Hand Hygiene Dividedly among Five Situations in Intensive Working in Namazi Hospital of Shiraz
Microbiology and Infectious DiseasesHand hygiene behavior divides into two categories: the innate hand hygiene and the selective hand hygiene. The innate ha...Read more
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Evaluation of the effect of saturated and unsaturated fatty acids on the growth and production of outer membrane vesicles in human gut microbiota
Microbiology and Infectious DiseasesA diverse and complex symbiotic microbial community colonize in human host,espicially in the gastrointestinal tract,refe...Read more
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Frequency of Binding Site at C-Terminal of Helicobacter Pylori CagA Separated from Gastric Tissue Biopsy of Patients with Gastroduodenal Disorders in Shafa Hospital in Khorramabad
Microbiology and Infectious DiseasesHelicobacter pylori (H. pylori) is a gram-negative, microaerophilic bacterium in gastric mucosa. It has a helical shape...Read more
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Effect of different Electromagnetic fields (EMF) on sperm viability and motility
Women and Reproductive HealthToday, due to the advancement of the level of technology, electromagnetic fields (EMS) from various industries affect...Read more
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Blood porphyrin fluorescence peaks and its diagnostic value for early colorectal cancer (CRC) detection
Cancer; Prevention, Diagnosis and TreatmentPorphyrins are precursors of Heme metabolism. Any metabolic disorder like cancer can highly affect their level. Since th...Read more
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Non-muscle Myosin Heavy Chain 9 Gene (MYH9) Polymorphism (rs4821481) is Associated with Urinary Albumin Excretion in Iranian Diabetic Patients
Medical GeneticsMyosin heavy chain 9 (MYH9) gene polymorphisms have been implicated in a different type of renal disease as well as neph...Read more
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Frequency of TET Resistance Gene and TEM Beta-Lactamase Resistance Genes in the Normal Flora of the Intestines of Addicted People Without symptoms of Intestinal Infection and Diarrhea, IRAN-Ahvaz City
Microbiology and Infectious DiseasesWide studies in National Institute for Drug Abuse(USA) are done with preventive goals, or risk and protective factors as...Read more
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In silico analysis of Siglec14 as a target for hsa-let-7e-5p
Medical GeneticsSialic acid-binding immunoglobulin-type lectins (Siglecs) are transmembrane proteins that are expressed on the cell surf...Read more
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Tamoxifen-induced rapid death of GPER positive cell lines by modulating RAS/MAPK signaling pathway
Cancer; Prevention, Diagnosis and TreatmentBreast cancer is the most common cancer in women worldwide. Tamoxifen is a nonsteroidal selective estrogen receptor modu...Read more
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the relationship between general and abdominal obesity and advanced glycation end products
Nutrition and HealthAdvanced glycation end products (AGEs) are a heterogeneous group of macromolecules that are formed by the non-enzymatic ...Read more
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Correlation between oral health status and salivary total antioxidant capacity in type 2 diabetes mellitus among Iranian adults
Metabolism and Metabolic DiseasesDiabetes mellitus is a chronic metabolic disease leading to several complications. Among these, dental caries are consid...Read more
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Progress and Prospect of Nanotechnology in Stem Cells
Nano-Biotech MedicalThe apparition of nanotechnology has paved the way for an obvious understanding of stem cell therapy in vivo and by repe...Read more
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One Step Toward Normal Heart Beat By Biological Pacemaker
Medical GeneticsCardiac electrical impulses are generated in sinoatrial node (SAN) which establishes spontaneous action potentials. SAN ...Read more
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Investigating the effects of saffron and melatonin with radiotherapy on viability of Hela cells
Cancer; Prevention, Diagnosis and TreatmentCancer is one of the biggest threats to human life. None of cancer treatment have not succeeded completely. One of the n...Read more
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Berberine induced apoptosis of HT-29 cells through mediating of miR-21
Cancer; Prevention, Diagnosis and TreatmentBerberine is an isoquinoline that can be extracted from many medicinal herbs. microRNAs (miRNAs) are small non-coding RN...Read more
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The Possible Role of B. thetaiotaomicron-derived Outer Membrane Vesicles (OMVs) in the Modulation of Cholesterol Uptake and Diet-induced Obesity
Metabolism and Metabolic DiseasesAltered gut microbiota composition has been proven to be associated with several disorders including metabolic syndrome....Read more
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Suppression of interfering predominant bacteria in purification of Myxobacteria
Microbiology and Infectious DiseasesMyxobacteria have recently gained attention due to the ability to produce numerous biological active metabolites. Applyi...Read more
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Anti-Diabetic Effects of Methanolic Extract of Calendula officinalis through Increased Antioxidant Enzymes Activity
Metabolism and Metabolic DiseasesDiabetes is a big challenge in the health care system. ROS generation is the major mechanisms which is involved in the p...Read more
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Fabrication and optimization of polymeric PAA nanoparticles loaded with the natural antibacterial component, curcumin.
Nano-Biotech MedicalCurcumin is a natural polyphenol molecule derived from the Curcuma longa plant which exhibits anticancer, antioxidant, a...Read more
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Curcumin regulates proinflammatory signaling function of thrombin in endothelial cells
Microbiology and Infectious DiseasesCurcumin regulates proinflammatory signaling function of thrombin in endothelial cells...Read more
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Lack of association between Hypoxia Inducible Factor rs11549465 polymorphism and Preeclampsia
Medical GeneticsPre-eclampsia (PE) is an obstetric disorder that may result inmaternal and neonatal mortality and morbidity. Placental h...Read more
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personalized medicine in oncology
Medical GeneticsThe term peronalized medicine is used for the identification of optimal drug type and optimal drug dosage for individual...Read more
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study of promoter methylation status of pax5 gene in patients with gastric cancer
Cancer; Prevention, Diagnosis and TreatmentGastric cancer is the fifth leading cause of cancer and is also the third leading cause of death in the world .Although ...Read more
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In silico epitope prediction and modeling for agent of smallpox and molecular docking for epitope-MHCâ… receptor
Medical GeneticsAlthough Variola and Vaccinia viruses have been Eradicated but still smallpox can be a serious problem for Societies. H3...Read more
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analysis of circulating mir-141, and mir-375 in small cell lung cancer patients
Medical Geneticslung cancer is the main cause of mortality from cancer in the world. small cell lung cancer is the most invasive lung ca...Read more
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Toll-like receptor 4 mediates cross-talk between peroxisome proliferator-activated receptor γ and nuclear factor-κB in mouse melanoma (B16F10) in vitro
Cancer; Prevention, Diagnosis and TreatmentThere is increasing evidence that chronic activation of nuclear factor-κB (NF-κB), which is an essential signaling pat...Read more
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studying the effect of silibinin in some of hippo signaling pathway genes , in T47D and MCF7 Breast cancer cell lines with 3D culture.
Cancer; Prevention, Diagnosis and TreatmentBreast cancer is one of the most common malignancy diseases world and is the second leading cause of cancer in women. S...Read more
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Additive Cytotoxic Effect of Apoptin and Chemotherapeutic Agent Docetaxel on LNCaP Cell Lines
Cancer; Prevention, Diagnosis and TreatmentUnfortunately although chemotherapy is primary therapy for most types of advanced prostate cancer, conventional chemothe...Read more
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Association of selenoprotein S expression and its variants with metabolic syndrome in subjects with cardiovascular disease
Metabolism and Metabolic DiseasesSelenoproteins S (SELS or VIMP) may regulate cytokine production, and thus play a key role in the control of the inflamm...Read more
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Effect of vitamin E on liver index enzymes in normal and CCl4-intoxified male Wistar rats
Nutrition and HealthVitamin E is the key lipid-soluble antioxidants in humans. Vitamin E supplementation was effective in decreasing markers...Read more
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Effect of LPS on regulatory T cell induction in peripheral blood mononuclear cells of endometriosis patients
Women and Reproductive HealthEndometriosis is an estrogen-dependent chronic inflammatory disease affecting women of reproductive age. Regulatory T ce...Read more
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Investigation efflux pump -activated fluoroquinolone resistance in pseudomonas aeroginosa multi drug resistance isolates by CCCP inhibitor
Microbiology and Infectious DiseasesPseudomonas aeruginosa is the third cause of nosocomial infections after Staphylococcus aureus and E. coli .One of the p...Read more
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The impact of miR-16 and miR-34a overexpression on the migratory and invasive potential of breast cancer cells
Cancer; Prevention, Diagnosis and TreatmentBreast cancer (BC) is the most frequent type of cancer and a main cause of cancer-related deaths among women worldwide. ...Read more
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Naltrexone changes the expression of lipid metabolism-relatedproteins in the endoplasmic reticulum stress induced hepatic steatosis in mice
Metabolism and Metabolic DiseasesEndoplasmic reticulum (ER) stress is closely associated with several chronic diseases such as obesity, atherosclerosis, ...Read more
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Study of Effects of Crushed PLGA Nano-fiber Percentage on The Cell Proliferation in Chitosan-Gelatin-βGlycerophosphate Cartilage Scaffold
Nano-Biotech MedicalArticular cartilage has poor reparative capabilities. So Osteoarthritis is widespread globally in almost 70% of people o...Read more
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EXPRESSION OF AN ANTIBODY FRAGMENT (SCFV) AGAINST AMYLOID-BETA USING T7 PROMOTER IN FED-BATCH CULTIVATION MODE
Microbiology and Infectious DiseasesIn the current investigation, the expression yield and solubility of Aβ antibody was analyzed using T7 promoter in fed-...Read more
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Role of MicroRNAs in Multiple Sclerosis
Medical GeneticsMultiple sclerosis (MS) is an autoimmune neurodegenerative disease in which the body’s natural defense system attacks ...Read more
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Correlation of umbilical coiling index and HbA1C in gestational diabetes mellitus (one-step strategy).
Metabolism and Metabolic DiseasesGestational diabetes mellitus [GDM] is a prevalent and potentially serious condition which may put mothers and fetuses a...Read more
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Dietary intake of antioxidants in elderly: A case-control study in Iran
Nutrition and HealthNutrient deficiencies such as antioxidants are common problems in elderly subjects which can result in different cancers...Read more
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Effect of hemodialysis on antioxidant enzyme levels in non- diabetic dialysis patients
Metabolism and Metabolic DiseasesDialysis patients are at a high risk for oxidative stress, resulting in an imbalance between the formation of free radic...Read more
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Shedding light on new form of combination therapy in acute promyelocyte leukemia
Cancer; Prevention, Diagnosis and TreatmentAlthough physicians have taken a variety approaches for the treatment of acute promyelocytic leukemia (APL), there is no...Read more
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Impact of GSTP1 genetic polymorphisms on susceptibility risk of chronic myeloid leukemia
Cancer; Prevention, Diagnosis and TreatmentGenetic variation influencing individual susceptibility to chemical carcinogens is one of the main factors leading to ca...Read more
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Mortality effect of Silibinin on the A549 cell line
Cancer; Prevention, Diagnosis and TreatmentLung cancer is the leading cause of cancer death in the world, with 1,375,000 deaths annually. Common chemotherapy such ...Read more
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Effect of Zinc Oxide Nanoparticles on expression of proapoptotic BAX and Bcl-2 in Testicular Tissue of NMRI Adult Mice
Nano-Biotech MedicalZinc oxide nanoparticles have numerous applications in medicine and industry. These materials are delivered to the tissu...Read more
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Study on protein of leech saliva of Hirudo Oreintalis, Utevsky & Trontelj 2005 in different ages
Nutrition and HealthMedicinal leech, during feeding, enter in host body many bioactive substances that often contain proteins and peptides. ...Read more
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Snake venom: an anticancer agent in immunotoxin therapy
Cancer; Prevention, Diagnosis and TreatmentCancer is the second leading cause of death worldwide. Therefore, many studies are underway to innovate more efficient t...Read more
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ISOLATION OF DEHALOGENASE PRODUCING BACTERIA FROM A MARINE ENVIRONMENT THAT CAN DEGRADE 2,2-DICHLOROPROPIONATE (2,2-DCP)
Microbiology and Infectious DiseasesMost halogenated compounds are major environmental pollutants.2,2-dichloropropionic acid is an organochloride herbicid...Read more
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Design and cloning of tanatin peptide in Pichia.pastoris and evaluation of its antifungal activity
Microbiology and Infectious DiseasesNowadays, control of fungal infections is one of the most important goals in the field of health. Therefore, developing ...Read more
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Evaluation of cytotoxicity, viability and induced oxidative stress by Nickel (II) complex of thiosemicarbazone
Cancer; Prevention, Diagnosis and TreatmentThiosemicarbazones and their metal complexes have significant biological activities including anticancer, antibacterial,...Read more
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Expression of NAV2 correlated with Change of tumor size in breast cancer patients
Cancer; Prevention, Diagnosis and TreatmentBreast cancer is the first leading cause of cancer death among Iranian women and the second worldwide. This type of canc...Read more
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Development of a chemiluminometric lateral flow biosensor for sensitive detection of Escherichia coli
Microbiology and Infectious DiseasesPaper based nucleic acid testing (NAT) has attracted significant interest in point of care diagnostic field. Lateral flo...Read more
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Benefical Effects of hydroalcoholic extract of fenugreek seeds on some Biochemical factors and oxidative stress in high-fructose diet-induced metabolic syndrome in rats
Metabolism and Metabolic DiseasesBackground: Fenugreek (Trigonella foenum graecum) is a traditional herbal plant. seeds of Fenugreek have several propert...Read more
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Optimization of the best concentration of Aloe vera extract for treating gastric cancer cells in order to reduce HER-2 gene expression
Cancer; Prevention, Diagnosis and TreatmentHER2 is a glycoprotein that has tyrosine kinase activity and plays an important role in guiding growth signals. Its expr...Read more
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Insulin resistance in addicted people: experimental study along with in vitro study and data mining Techniques
Metabolism and Metabolic DiseasesThis study was planned to survey the inflammatory and antioxidant and other Insulin Resistance related condition in addi...Read more
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A genetic variant in Multiple drug resistance gene is associated with poor prognosis of patients with esophageal squamous cell carcinoma
Cancer; Prevention, Diagnosis and TreatmentEsophageal squamous cell carcinoma (ESCC) is one of the causes of death from cancer. Several genetic variants in the 7q2...Read more
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The latest developments in pharmaceutical biotechnology
Nano-Biotech MedicalBackground and Aim: Biotechnology has produced over 200 types of drugs and new vaccines that include products for the tr...Read more
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Lipase adsorbtion on the single layer geraphene oxide dependes on pH and temperature
Nano-Biotech Medicalgraphene oxide (GO) has been used as a matrix for lipase immobilization. GO chemical properties are reported beneficial ...Read more
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Gene Bookmarking, a way to detect, predict and control molecular processes
Medical GeneticsGene bookmarking is a mechanism of epigenetic memory for gene expression transmission programs, during cell division. ...Read more
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Gene expression profiling of the 8q22-24 position in human breast cancer: TSPYL5, MTDH, ATAD2 and CCNE2 genes are implicated in oncogenesis, while WISP1 and EXT1 genes may predict a risk of metastasis
Cancer; Prevention, Diagnosis and TreatmentGene expression profiling has been suggested to predict breast cancer outcome. The prognostic value of the 8q22 24 posit...Read more
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Evaluation of magnesium & copper levels and antioxidant power in serum of women with endometriosis before and after administration of N-acetylcysteine
Women and Reproductive HealthEndometriosis is caused by the presence of ectopic endometrial stromal outside the endometrial cavity. The oxidative str...Read more
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HETEROGENEITY OF ESCHERICHIA COLI ISOLATES WITHIN DIFFERENT
Microbiology and Infectious DiseasesAim:Escherichia coli is one of the most important bacterial pathogens causing urinary tract infections (UTIs) . This bac...Read more
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Silver nanoparticles potential as an adjuvant in antimicrobial therapies against multidrug resistant bacteria
Microbiology and Infectious DiseasesThe emergence and rapid spread of multidrug-resistant (MDR) isolates of pathogenic bacteria causing nosocomial infection...Read more
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Effects of serotonin on adiponectin secretion and leptin gene expresions in rats
Women and Reproductive HealthSerotonin is a neurotransmitter which stimulates the secretion of sexual hormones . The nuclei of Hypothalamus involved...Read more
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Investigating the specificity of the specific lytic bacteriophage against Salmonella bacteria and its effect on the hep2 cell line
Microbiology and Infectious DiseasesResistance to antibiotic treatments is one of the increasing problems. Therefore, alternative methods to reduce antibiot...Read more
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Wound healing effect of Tea tree oil on Methicillin Resistant Staphylococcus aureus (MRSA) : an Animal Study
Microbiology and Infectious DiseasesTea tree oil (TTO), or melaleuca oil, is an essential oil with a fresh camphoraceous odor and a color that ranges from p...Read more
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Study of DNA binding and cytotoxic activity of a benzochromene derivative
Cancer; Prevention, Diagnosis and TreatmentDNA is currently a target for some of the drugs used in cancer therapy. Among the various treatment strategies for remov...Read more
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Detection of methylated DNA based on graphene quantum dot -DNA interaction
Nano-Biotech MedicalEpigenetics is the study of interaction between genes and their expressed product which is controlled by some specific c...Read more
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FGF10: Type III Epithelial Mesenchymal Transition and Invasion in Breast Cancer Cell Lines
Cancer; Prevention, Diagnosis and TreatmentMetastasis is one of the important characteristics of a cancer cell. the process called epithelial mesenchymal transitio...Read more
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Antiangiogenic Effect of Endostatin-derived Peptides on a Mouse Model of Colon Cancer
Cancer; Prevention, Diagnosis and TreatmentColon Cancer is among the most common malignancies worldwide. Angiogenesis is the formation of new microvasculature thro...Read more
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Interference of Dopamine D2 Receptors and Food Restriction on Changing Anxiety Behavior and Serum Biochemical Factors in Adult Male Rats
Nutrition and HealthBackground: Food restriction (FR) and dopaminergic system affect on anxiety behavior, but it has not been determined the...Read more
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Investigation of cytotoxicity, cell cycle and induction of apoptosis by methyl-thiosemicarbazone complex with Cu2+ in K562 cell line
Cancer; Prevention, Diagnosis and TreatmentThiosemicarbazone compounds have previously been considered as a new series of potent apoptosis-inducing agents. In the ...Read more
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The giant lipoma pediculated in the falciform ligament: a case report
Cancer; Prevention, Diagnosis and TreatmentIntroduction: Lipoma is one of the benign and common tumors of the limbs and trunk that’s rarely occurs in the abdomin...Read more
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Preparation and assessment of chitosan-polyethylenimine-carboxymethyl dextran nanoparticles for efficient siRNA delivery in vitro
Nano-Biotech MedicalAmong polycation nanoparticles, chitosan nanoparticles (Ch) have emerged as promising carriers for gene delivery, nevert...Read more
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Comparison of Antibacterial Activity of Essential Oil of Varieties of Calendula Plant from Varamin (Iran) on Escherichia coli and Staphylococcus aureus
Microbiology and Infectious DiseasesUncontrolled use of conventional antibiotics and synthetic antibacterial medicine has led to the proliferation of microb...Read more
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Identification of Oral strains of Lactobacillus.species in patients with chronic periodontitis and healthy individuals
Microbiology and Infectious DiseasesOral infections constitute some of the most common and costly forms of infections in humans.Chronic periodontitis has be...Read more
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Investigation of deaths caused by cancer in Bandar Anzali in 2014
Cancer; Prevention, Diagnosis and TreatmentCancer is one of the main causes of death and disability in Iran and the world. This study was conducted to evaluate the...Read more
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Marine Biotechnology in public health and food safety
Nutrition and HealthSea and oceans make up more than 70 percent of the Earth's surface, and on the other hand, more than 80 percent of livin...Read more
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Frequency of Escherichia coli O157:H7 among children with and without diarrhea stool samples referred to microbiology laboratory of shahid Madani Hospital in KhorramAbad during 2016-2017.
Microbiology and Infectious DiseasesEscherichia coli serotype O157:H7, which has been recognized as a food-borne pathogen occurring worldwide in the recent ...Read more
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Effect of Extract of Origanum Vulgare on the activity of alanine aminotransferase enzyme in healthy and diabetic mice
Metabolism and Metabolic DiseasesWild Thyme is a great medicinal plant that grows in different areas of the Mediterranean and some parts of Asia.Present ...Read more
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The effect of Chlorogenic acid on Insulin, GIP and GLP-1 level in healthy humans: A systematic review
Nutrition and HealthAccording to previous studies, there are different supplements in order to prevent and treat diabetes. These studies sho...Read more
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Can air pollution impact of sperm parameters? A meta- analysis
Women and Reproductive HealthAir pollution is common in all countries and affects reproductive functions in men and women. It particularly impacts sp...Read more
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Higher efficacious delivery in non-toxic dose of Genistein to AML cells by its conjugation on Superparamagnetic Fe3O4 Nanoparticles decorated with bio-compatible Carboxymethylated Chitosan
Nano-Biotech MedicalGenistein is an isoflavone with anti-cancer properties, but effective dosage against malignant cells was not in non-toxi...Read more
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Design And Application Of A Loop-Mediated Isothermal Amplification (LAMP) Assay For Detection Of Tick Borne Relapsing Fever
Medical GeneticsTick borne relapsing fever (TBRF) caused by Borrelia microti is transmitted via bites of the soft tick Ornithodoros erra...Read more
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The effect of diet in preventing of colorectal cancer: A systematic Review
Cancer; Prevention, Diagnosis and TreatmentColorectal cancer (CRC) is the third most commonly diagnosed cancer in worldwide and it is established that diet has an ...Read more
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Evaluation of Salmonella.spp in Synovial Fluids of Arthritis Patients by Molecular Method
Microbiology and Infectious DiseasesArthritis is an inflammation of the joints. This complication is often accompanied by pain, swelling, stiffness and heat...Read more
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Intervention of Dopamine D2 Receptors in Regulating the Serum Lipid Profile in Male Rats under Food Restrictions
Nutrition and HealthStudies have indicated that reduced energy consumption mostly has a significant effect on the reduction of blood lipids...Read more
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Evaluation and comparison of digestion in two traditional and contemporary medicine schools And its effect on the treatment of diseases
Nutrition and HealthIn traditional medicine, one of the three most important nutritional principles is digestion. In our digestion, we deal ...Read more
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Investigation of microRNAs involved in the EGFR molecular pathway as a biomarker in early detection of colorectal cancer
Medical GeneticsColorectal cancer (CRC) is one of the most common cancers in the world. The highest incidence of CRC in Europe, North Am...Read more
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Polymorphisms evaluation of the thiopurine S-methyltransferase gene among the Iranian acute lymphoblastic leukemia population
Medical GeneticsThiopurine S-methyltransferase (TPMT) is a cytosolic enzyme which catalyzing the S-methylation of 6-mercaptopurine and...Read more
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The levels of VDBP in patients with chronic rhinosinusitis with polyposis
Medical GeneticsChronic rhinosinusitis (CRS) is a prevalent disease which is characterized by chronic inflammation of the nasal mucosa ...Read more
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Association between Biochemical Markers BHCG in Screening First Trimester of Pregnancy in Women with PCOS
Women and Reproductive HealthPCOS (polycystic ovary syndrome) is a common endocrine system disease among women of reproductive age. Its prevalence in...Read more
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Familial occurrence of Mayer-Rokitansky-Küster-Hauser syndrome in two siblings in Iran
Medical GeneticsFamilial occurrence of Mayer-Rokitansky-Küster-Hauser syndrome in two siblings in Iran Asadi fatemeh 1*, shokouholsa...Read more
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Design and evaluation of a selective delivery system to induce antimiR-155 function
Nano-Biotech MedicalDeveloping RNA/DNA aptamer-miRNA chimera represents an effective approach in targeted gene therapy of cancer. In additio...Read more
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Investigating the role of exon7 axin2 in colorectal cancer (Laboratory and bioinformatics studies)
Cancer; Prevention, Diagnosis and TreatmentIn Iran, colon cancer is the third most common cancer. WNT pathway changes are commonly reported in this cancer. Among t...Read more
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miR-214 induces insulin resistance in C2C12 cell line though targeting Rock1 and Akt2 gene expressions
Metabolism and Metabolic DiseasesMicro-RNAs (miRNAs) are a class of post-transcriptional regulators that play crucial roles in various biological process...Read more
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Effect of Praziquantel Drug on Prevention of Afflicting Dogs with Cestode Echinococcus Granulosus
Microbiology and Infectious DiseasesAwareness of the impact range of praziquantel drug on prevention of afflicting dogs with echinococcus granulosus parasit...Read more
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Study of gene expression and promoter methylation pattern of AKAP4 as possible breast cancer diagnostic marker candidate
Cancer; Prevention, Diagnosis and TreatmentBreast cancer is an important health issue for millions of women around the world. Recently, a new group of tumor-associ...Read more
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Association between Heat shock protein 70 gene polymorphism and risk of multiple sclerosis in Iranian population
Medical GeneticsMultiple sclerosis (MS) is a chronic disease of the central nervous system and one of the most common causes of neurolog...Read more
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The Anticancer Effect of Plant Aqueous Extracts of Aloe Vera in Gene Expression Bax and Bcl-2 on Gastric Adenocarcinoma AGS Cells
Cancer; Prevention, Diagnosis and TreatmentGastric cancer is a major cause of cancer death. In terms of incidence is the fourth most common cancer and the second l...Read more
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Toxoplasmosis infection in the pregnant women in the first trimester in yasouj city
Women and Reproductive HealthToxoplasmosis is a shared human-animal disease with worldwide distribution caused by Toxoplasma gondii. More than half o...Read more
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Determining the Interactions between Major Dietary Patterns and LRP5 Genotypes (rs556442) on Bone Discordance in Postmenopausal Women Referred to Shariati Hospital
Nutrition and HealthOne of the challenges in the diagnosis of osteoporosis is bone discordance. Many studies have confirmed an association ...Read more
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Development and implementation of a novel panel consisting 16 STR markers linked to the HLA-gene-cluster applicable for HLA-typing, PND&PGD
Medical GeneticsPGD (Pre-implantation Genetic Diagnosis) in combination with human leukocyte antigen (HLA) matching, allow not only sele...Read more
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CRISPR/Cas9-mediated gene Knockout
Cancer; Prevention, Diagnosis and TreatmentGenome engineering is a novel and powerful tool for biotechnological applications. The development of the Clustered Regu...Read more
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conjugation DNA aptamer HER-2 and anti mir-21 as a pharmaceutical agent targeted for apoptosis in MCF7cancer cell line
Cancer; Prevention, Diagnosis and TreatmentIn the past decade, it has become apparent that certain small RNA plays an important role in the initiation, progression...Read more
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Overview the Challenges and Development of regenerative medicine in future
Stem cell and Medical ApplicationsMore than 2000clinical trials relating stem cells, there is not a single clinical difficult that is regularly treated wi...Read more
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Cucurbitacin D from Ecballium elaterium (L.) A. Rich upregulates BCL-2 gene in human gastric cancer cell line AGS
Cancer; Prevention, Diagnosis and TreatmentMedicinal plants are potential sources of new drugs and natural therapies based on them are becoming increasingly import...Read more
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Investigation of synergies effects of albumin- amino penicillin on Staphylococcus aureus MRSA
Nano-Biotech Medicalduring the recent decades, Nanotechnology has entered the field of drug industries and importance of nano-drugs in curin...Read more
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Classification of Genes Related to Infectious Disease: New Hybrid Method for High Imbalanced Data Sets
Medical GeneticsGene functionality explorations has a great importance in health science research. Developing gene classifiers having ac...Read more
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Relation between Resilience and Psychiatric Disorders in Patients with Aids in Bandar Abbas Center for Behavioral Diseases
Nutrition and HealthThe AIDS process is very complex and can significantly affect the physical, social, spiritual and psychological health o...Read more
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Relationship between Hypertension in the First Trimester of Pregnancy with Weight and Height at Birth
Women and Reproductive HealthBackground: Hypertensive disorders with a prevalence of %5-10 are among the main causes of morbidity and mortality in mo...Read more
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Molecular study of 92 fetal of couples with recurrent abortion in Mazandaran
Medical GeneticsChromosome abnormalities has recognized as a major factor contributing to pregnancy loss and accounted for about 50% of ...Read more
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The role of oils in breast cancer in women (systematic review)
Cancer; Prevention, Diagnosis and TreatmentAbout one-third of cancers may be related to diet, along with lifestyle and physical activity. International data show t...Read more
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Evaluation of toxicity of functionalized graphene with ginsenoside Rh2, Lysine and Arginine on RBCs, blood coagulation and cardiovascular tissue: In vitro and In vivo study
Nano-Biotech MedicalIn this study, blood and cardiotoxicity of functionalized graphene with ginsenoside Rh2 (Rh2), Lysine and Arginine was e...Read more
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Prevalence of gastric cancer in the patients undergoing bariatric surgery
Cancer; Prevention, Diagnosis and TreatmentIntroduction and goal: The number of obese people has grown up to 1.9 billion worldwide, that a large number of complica...Read more
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Anticancer Application of Camel Milk: A Review of Recent Research
Cancer; Prevention, Diagnosis and TreatmentBecause of importance of cancer and the side effects of existing therapies, it is essential to find new therapeutic stra...Read more
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case report of Albinism with pseudo dominant inheritance
Medical GeneticsOculocutaneous albinism type 1 is characterized by hypopigmentation of the skin and hair and the distinctive ocular chan...Read more
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Effect of DNA Demethylating Agent Genistein on Epigenetic-modifying Estrogen Receptor Alpha Gene Expression and Apoptosis Induction and also Cell Viability in Hepatocellular Carcinoma HepG 2 cell line
Cancer; Prevention, Diagnosis and TreatmentIn the normal mammalian cells, epigenetic changes such as DNA methylation and histone acetylation play an important role...Read more
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the effect of Lactobacillus acidophilus (La) and Lactobacillus rhamnosus (Lr) on proliferation and invasion of Colorectal cancer cells (Caco2).
Cancer; Prevention, Diagnosis and TreatmentColorectal cancer is one of the most common epithelial cancers in the world. Many studies have been conducted on the inh...Read more
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Sun protection factor (SPF) determination of sericin cream and niosomal gel
BeautySericin is a protein extracted from silk and has antioxidant, antimicrobial, antineoplastic, wound healing and moisturiz...Read more
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Investigating the incidence of cardiovascular in patients with ercutaneous coronary interventionin Bandar Abbas Shahid Mohammadi Hospital
Metabolism and Metabolic DiseasesPCI(Percutaneous coronary intervention) is one of the most common mode of re vascularization. so According to the impo...Read more
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Production and evaluation of scFvs against HER2 antigen for breast cancer immunotherapy
Cancer; Prevention, Diagnosis and TreatmentBreast cancer is common cause of women death in the world. There is ErBb2/HER2 in 25%-30% breast cancer cases. Trastuzu...Read more
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Detection of Borrelia microti in blood samples spotted on DNA Banking Card by using Loop-Mediated Isothermal Amplification (LAMP)
Medical GeneticsTick-borne relapsing fever (TBRF) is an endemic disease in Iran, with more 100 annual cases. The glycerophosphodiester ...Read more
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Evaluation of PRC1 gene expression in gastric cancer patients
Cancer; Prevention, Diagnosis and Treatment: Cancer is one of the most important causes of death. Among cancers, gastric cancer is the fourth most common cancer an...Read more
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Role of Potential tumor marker in several cancer: Diagnostic and Treatment
Cancer; Prevention, Diagnosis and TreatmentTumor markers are substances produced by the tumors or by other cells of the body in response to cancer. They are produc...Read more
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Effect of folic acid supplementation on acute effects of trimethoprim/sulfamethoxazole on histopathological changes in the testes of adult male rats
Stem cell and Medical ApplicationsMale infertility has been reported following long-term sulfasalazine use for ulcerative colitis treatment. However, the ...Read more
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Detection of Mycoplasma arginini contamination in biological products by PCR
Microbiology and Infectious DiseasesIntroduction: Mycoplasmas are one of the most important pollutants in biological products and cell cultures, and are a...Read more
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The efficacy of Leptin on physical and psychological stress causing gastric ulcer: Participations of nitric oxide and prostaglandin E2
Nutrition and HealthThe present study aimed to assess the effects of Leptin on physical and psychological stresses inducing gastric ulcer. T...Read more
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Biosynthesis of Tellurium nanoparticles by Streptomyces isolate B2.1369F
Nano-Biotech MedicalBiosynthesis of Tellurium nano particles (TNPs) has great advantage since it has no chemical contamination in the enviro...Read more
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Alterations of gyrA in Enterobacteriaceae isolated of urinary tract infection resistance to quinolones antibiotics
Microbiology and Infectious DiseasesUrinary tract infection is one of the most common infections, which if not treated, it can be cause seriouse problem in ...Read more
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MOLECULAR DETECTION OF GUT BACTERIA LACTOBACILLUS, BIFIDOBACTERIA, CLOSTRIDIUM DIFFICILE AND YEAST IN BOWEL DISEASE AND CONTROL PATIENTS
Microbiology and Infectious DiseasesTwo kinds of intestinal disorders included inflammatory bowel disease and irritable bowel syndrome have a strong negativ...Read more
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Reproductive Health Training Program on Students in IRAN: An Action Research Approach
Women and Reproductive HealthTransition from adolescence to adulthood is one of the important periods in the individual life. New behaviors are learn...Read more
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A genetic variant in CDKN2A/2B locus was associated with poor prognosis in patients with esophageal squamous cell carcinoma
Cancer; Prevention, Diagnosis and TreatmentEsophageal squamous cell carcinoma (ESCC) is among the leading causes of cancer related death. Despite extensive efforts...Read more
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Effects of 5-aza-2ˈ-deoxycytidine and Valproic Acid on Epigenetic-modifying DNMT1 Gene Expression, Cell Growth Inhibition and Apoptosis Induction in Hepatocellular Carcinoma WCH-17 cell line
Cancer; Prevention, Diagnosis and TreatmentIntroduction DNA molecule of the eukaryotic cells is found in the form of a nucleoprotein complex named chromatin....Read more
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TP53 hotspot mutations and expression of c-Myc oncogenes in astrocytoma and meningioma
Medical GeneticsMost studies have shown that there are association between the development and malignancy of brain tumors and tumor supp...Read more
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Evaluation of nitrate and nitrite content in meat and meat products and their role of these substances in carcinogenesis
Cancer; Prevention, Diagnosis and TreatmentBecause of N-nitrous compounds formation in meat and meat products, There is a direct correlation between high consumpt...Read more
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Therapeutic effect of Human Tumor Necrosis Factor Receptor-2 on collagen -induced arthritis in Balb/c mice
Metabolism and Metabolic DiseasesRheumatoid arthritis (RA) is a chronic, systemic, immune-mediated inflammatory disease associated with decreased life ex...Read more
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The role of lipids in the pathogenesis of Human T-cell leukemia virus-1 (HTLV-1) infection: a review of literature
Microbiology and Infectious DiseasesHuman T cell lymphotropic virus-1 (HTLV-1) is an oncogenic retrovirus which can cause adult T-cell leukemia lymphoma (AT...Read more
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Analysis of hypermethylation of NFK-B ØŒTRAF1 and TRAF2 genes in patients with oral squamous cell carcinoma
Medical GeneticsCancer is a fatal disease caused mainly by environmental factors that mutate genes encoding critical cell-regulatory pr...Read more
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The prevalence of adeABC encoding genes among Acinetobacter baumannii carbapenem resistant clinical isolates.
Microbiology and Infectious DiseasesAcinetobacter baumannii is the important cause of nosocomial infections worldwide due to its propensity to rapidly acq...Read more
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A study on the interaction of angiotensin I converting enzyme inhibitory peptide with human hemoglobin protein by conductometry method in the absence and presence of a low frequency electromagnetic fi
Metabolism and Metabolic DiseasesHigh blood pressure, or hypertension, is a chronic disease in which the blood pressure goes up. Angiotensin converting e...Read more
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Evaluation of the effects of fish oil-derived Eicosapentaenoic acid on the proliferation of colorectal cancer cell line (hct116)
Cancer; Prevention, Diagnosis and Treatmentof these studies have indicated that Eicosapentaenoic acid (EPA) can induce apoptosis and reduce proliferation in cancer...Read more
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Evaluation and study of antimicrobial activity of nanoliposomal meropenem against Pseudomonas aeruginosa isolates
Nano-Biotech MedicalThe aim of this study was to evaluate the antimicrobial efficacy of liposomal meropenem formulation against clinical and...Read more
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Green synthesis of Silver nanoparticles by Alhagi camelorum gum
Nano-Biotech MedicalSilver nano particles (AgNPs) are used in textiles, cosmetics, tooth brushes, home appliances, food packages and many ot...Read more
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Role of NBD and DBD in P- glycoproteinfunction, a Molecular dynamic simulation
Cancer; Prevention, Diagnosis and TreatmentP-glycoprotein (P-gp) is an ATP-binding cassette (ABC) transporter which belongs to multidrug resistance pump super fami...Read more
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Evaluation of Adenovirus in Pseudomonas aeruginosa susceptible keratitis by PCR molecular method
Microbiology and Infectious DiseasesKeratitis is inflammation of the cornea of the eye. In keratitis, microbial agents are important. In the presence of inf...Read more
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Design, production and purification of polyclonal antibodies against recombinant human erythropoietin antigens for immunological investigation of pharmaceutical and clinical samples
Nano-Biotech MedicalIn this research, the primary antibody against erythropoietin is produced by injecting pure recombinant human erythropoi...Read more
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Evaluating Anticancer Effects of Tamarix ramosissima on A549 Cells
Cancer; Prevention, Diagnosis and TreatmentLung cancer is the leading cause of cancer death all over the world. Using plant derived materials as folk remedy has be...Read more
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Frequency and Pattern of Resistance of AmpC-Beta-lactamase gene in Clinical isolates of Klebsiella pneumoniae from Zahedan Educational Hospitals
Microbiology and Infectious DiseasesThe detection of CTX-M-15 genes in ESBLs produced by Klebsiella pneumoniae strains provides useful information on epidem...Read more
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Identifying Linking Mechanisms of Allergy and Cancer
Cancer; Prevention, Diagnosis and TreatmentAllergy and cancer are prevalent diseases and cause a lot of morbidity and mortality. In recent years, many studies have...Read more
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Involvement of Mu Opioid Receptor Signaling in the Protective Effect of Opioid against 6-Hydroxydopamine-Induced SH-SY5Y Human Neuroblastoma Cells Apoptosis
Cancer; Prevention, Diagnosis and Treatment1. Introduction arkinson’s disease (PD) is a neurodegenerative disease caused by losing dopaminergic neurons of the ...Read more
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Genes involved into both alternative splicing and aging pathways as biomarkers for Parkinson Disease diagnosis
Medical GeneticsParkinson's Disease is a degenerative movement disorder that exhibit symptoms through progressive loss of dopaminergic...Read more
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Poly(A)-tail shortening Length: an Alternative Epigenetic Mechanism for Translational Control of Oncogenes
Medical Genetics: mRNA poly(A) tails in 3'UTR is important for its stability and translation. t is observed Poly(A) tails is dynamic and...Read more
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Treatment of vitamin D deficiency in pregnancy
Women and Reproductive HealthThe purpose of this study is the importance of Vitamin D in pregnancy and its treatment. Serum levels of Vitamin D in th...Read more
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Determination of antibiotic-resistant strains of isolated Brucella in Markazi Province
Microbiology and Infectious DiseasesBrucellosis is one of the common diseases of man and animals are caused by bacteria of the genus Brucella. The purpose o...Read more
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Study of HER2 gene expression in AGS cell line after treatment of cells with Crocus sativus (Iranian Saffron) extract
Cancer; Prevention, Diagnosis and TreatmentThe study of HER-2 gene in cancers, especially gastric cancer, is of great importance. This gene, has been shown to inc...Read more
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Study genetic susceptibility polymorphisms for chronic lymphocytic leukemia in Iranian population.
Medical GeneticsChronic lymphoid leukemia (CLL) is the most common form of leukemia found in adults. CLL is a monoclonal disorder that w...Read more
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microRNAs as potential biomarkers in early detection of Breast cancer
Cancer; Prevention, Diagnosis and TreatmentBreast cancer is one of most worrisome health problems in women across the world. Its incidence and mortality have under...Read more
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Effect of Staphylococcus aureus isolates in food samples on hep2 cell line
Microbiology and Infectious DiseasesStaphylococcus aureus produces a range of protein-rich toxins and also extracellular pathogens that contribute to bacter...Read more
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Association of rs699 Polymorphism in AGT Gene with Coronary Heart Disease Risk
Medical GeneticsThe rs699 transition in human angiotensinogen (AGT) gene, result in methionine (M) to threonine (T) substitution at codo...Read more
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Comprehensive databank of Iranian patients with Noonan syndrome
Medical GeneticsNoonan syndrome (NS) (OMIM 163950) considered as a relatively common (1/1000-2500), developmental, multi-organ and compl...Read more
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Thiolated chitosans development and in vitro evaluation of apermeation enhancing oral drug delivery system
Nano-Biotech MedicalThis study investigated the in vitro release of Vancomycin and Amphotericin B fromnovel mocuadhesive chitosan nanofibers...Read more
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Effect of intracerebroventricular injection of Adenosine on food and fat intake in neonatal chicks
Nutrition and HealthThe present article was aimed to clarify the role of central Adenosine on food intake in neonatal chicks. Adenosine is n...Read more
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A Comparison of the efficacy of Fluconazole-loaded PLGA Nanospheres and Fluconazole on attachment of Candida albicans to hela cell
Microbiology and Infectious DiseasesThe human pathogenic fungus Candida albicans is commonly found on mucosal surfaces, such as the vagina. It has been wide...Read more
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The effects of vitamin D3 supplement on clinical course of patients with migraine
Nutrition and HealthMigraine is one of the most common headaches all around the world including Iran. Considering that some studies have sho...Read more
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Motor neuron differentiation potential of human umbilical cord blood- derived mesenchymal stem cells, in vitro
Stem cell and Medical ApplicationsMany people suffer from spinal cord injuries annually. These deficits usually threaten the quality of life of patients. ...Read more
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The Effects of MicroRNAs on Bone Regeneration and Differentiation
Medical GeneticsOne of the promising approaches for osteoporosis treatment is bone regeneration. In this case, several therapeutic optio...Read more
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ELISA Cross-Reactivity method to confirm recombinant fliC from salmonella typhimurium and evaluate impurities in purified recombinant protein
Microbiology and Infectious DiseasesRecombinant proteins as important materials for biomedicinal research, need high level of purity in order to be used in ...Read more
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The Relationship between STR-PCR Chimerism Analysis and Chronic GvHD Following Hematopoietic Stem Cell Transplantation
Cancer; Prevention, Diagnosis and TreatmentGraft-versus-host disease (GvHD) is one of the serious complications of HSCT. Its prevalence has been reported as 20-50 ...Read more
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Frequency of [aac(6’)-Ie-aph(2â€)] gene and aminoglycosids drug resistance in clinical Staphylococcus aureus isolates by two phenotype and molecular methods
Microbiology and Infectious DiseasesStaphylococcus aureus is one of the most common bacterial infection, these bacteria are an agent of nosocomial and commu...Read more
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Molecular Cloning of Clostridium perfringens Type D & Clostridium septicum vaccine strain epsilon alpha fusion gene in E. coli
Medical GeneticsDesigning and producing a proper fusion construction is the most important problem of producing large quantities of fu...Read more
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Cancer Stem Cell Therapy Based on Nanostructure Drug Vehicle, PMBN-IL3-GA
Nano-Biotech MedicalTo overcome difficulty of cancer treatment by conventional chemotherapy methods, the targeting drug delivery based on Na...Read more
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Targeted killer gene therapy of breast cancer cells using Pseudomonas exotoxin A
Cancer; Prevention, Diagnosis and TreatmentTargeted expression of killer genes in tumor cells ensures specific elimination of cancer cells with minimal effect on n...Read more
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Sensitivity of levofloxacin in combination with ampicillin-sulbactam and tigecycline against multidrug-resistant Acinetobacter baumannii
Microbiology and Infectious DiseasesDuring the last decades, emergence of antibiotic resistance among A. baumannii has been considered as a worldwide alarm....Read more
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Recombinant fibroin containing the RGD motif enhances limbal mesenchymal stromal cell adhesion and proliferation
Stem cell and Medical ApplicationsAt the periphery of the cornea, in a region called the limbus, exists a population of stromal progenitor cells termed li...Read more
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Overexpression of cancer stem cell protein, Piwil2, promotes the expression of anti-apoptotic and proliferative genes in the gastric cancer cell line MKN-45
Cancer; Prevention, Diagnosis and TreatmentPiwi-like RNA-mediated gene silencing 2 (Piwil2) is an oncogene that is highly expressed in different tumors including ...Read more
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Diet and lifestyle habit imoact on bone density in postmenopausal women
Nutrition and HealthMenopause is the stage of a woman's life, typically between the ages of 45 and 55, when she stops having menstrual perio...Read more
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Detection of macrolid and fluoroquinolones resistance among campylobacters isolated from diarrhea patients in Markazi province - 2015
Microbiology and Infectious DiseasesCampylobacter species, especially C. jejuni and C. coli, are the most common bacterial causes of gastroenteritis in huma...Read more
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Integrin Beta-3 gene polymorphism and risk for myocardial infarction in premature coronary disease
Medical GeneticsContradictory results have been obtained regarding the role of integrin, beta 3 (ITGB3) gene polymorphisms in occurrence...Read more
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Promoter Hypermethylation Analysis of the Tumor Suppressor Gene RASSF1A in Iranian Endometrial Carcinoma Patients
Cancer; Prevention, Diagnosis and TreatmentEndometrial cancer is the most common malignancy among women in developed countries. More endometrial cancers occurs in ...Read more
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A novel technique to estimate sex ratio in semen
Women and Reproductive HealthOffspring sex is one of the most important factors in controls sex-linked genetically transferred diseases and also for ...Read more
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Endurance training resulted in significantly greater betatrophin responses compared with resistance training alone, and resistance and endurance exercises combined
Metabolism and Metabolic DiseasesBetatrophin, which recently identified, is a liver and adipose tissue produced hormones that regulates the level of lipi...Read more
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Determination of GPR55 overexpression by quantitative real-time PCR as a biomarker for skin SCC detection
Cancer; Prevention, Diagnosis and TreatmentChronic wounds resemble the wounds arising with skin squamous cell carcinoma (SCC). Since they are cancerous, they shoul...Read more
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Neuroprotective nature of adipokine resistin in the early stages of focal cerebral ischemia in a stroke mouse model
Metabolism and Metabolic DiseasesThe goal of the present study was to test the dose-dependent and time-dependent effects of mouse recombinant resistin in...Read more
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Silencing of Mcl-1 and Bcl-2 by miR-15 Induces Apoptosis and Increases the Chemosensitivity of the CLL Cells
Cancer; Prevention, Diagnosis and TreatmentDespite advances in cancer therapy, drug resistance is a major problem in leukemia. Overexpression of anti-apoptotic pro...Read more
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Effect of EMF on Semen TBARS Concentration
Women and Reproductive HealthElectrical instruments in human life by development of applications causes new biological phenomenon in this century. Ne...Read more
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The role of natural antioxidants in treatment of cancer
Cancer; Prevention, Diagnosis and TreatmentCancer is one of the most common causes of death in advanced industrial societies. With the prevalence and spread of can...Read more
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Cytotoxic activity of Berberine on the growth of breast cancer cell line (MCF-7)
Cancer; Prevention, Diagnosis and TreatmentMuch research has been conducted on the benefits of various phytochemicals in many herbs, fruits and vegetables and thei...Read more
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Evaluation of Catalase (CAT) expression in Acute Myeloid leukemia Patients
Cancer; Prevention, Diagnosis and TreatmentAcute myeloid leukemia is a heterogeneous neoplastic malignancy, that despite considerable progress in many of its molec...Read more
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Has Clusterin gene a role in spermatogenesis?
Women and Reproductive HealthAzoospermia is a male disorder observed in 1% of the general population and in 10–15% of infertile men that is defined...Read more
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Evaluating the genetic variations in functional domains coding regions of MSMB in infertile men with unexplained infertility
Medical GeneticsÎ’-Microseminoprotein(MSMB) is one of the most abundant proteins in human seminal plasma. This protein binds to head and...Read more
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Comparative miR34a expression profile analysis in tumor and normal tissues of patients with colorectal cancer
Cancer; Prevention, Diagnosis and TreatmentColorectal cancer is a type of prevalent cancers in populations and allocates numbers of mortality. Recently, researcher...Read more
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Non-syndromic obesity in infertile men and structural chromosomal abnormalities
Medical GeneticsObesity is commonly classified into subgroups depending on suspected etiology: monogenic obesity (extremely severe obesi...Read more
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Potentiation of mitomycin C-induced apoptosis by lithium chloride in MDA-MB-231 breast cancer cells
Cancer; Prevention, Diagnosis and TreatmentBreast cancer is the principle cause of cancer mortality in females. Mitomycin C (MMC), as a potent antitumor drug, is u...Read more
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Detecting of herpes simplex virus’s DNA in the breast tumor, using polymerase chain reaction technique
Medical GeneticsIt has been proven that cancer cells formation can be due to the herpes simplex virus infection in human beings. The ai...Read more
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Influence of CYP2D6 and CYP3A4 genetic polymorphisms on susceptibility risk of chronic myeloid leukemia and treatment response
Cancer; Prevention, Diagnosis and TreatmentXenobiotic- metabolizing enzymes compose an important line of defence against a variety of carcinogenes and environmenta...Read more
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BRCC2 gene inhibits lung cancer cell proliferation and invasiveness in vitro and in vivo:Prospect for gene therapy
Cancer; Prevention, Diagnosis and TreatmentLung cancer is one of the major causes of cancer related death worldwide .Despite recent improvements, resistance to con...Read more
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The effect of celastrol on gene expression of TNF-α (Tumor necrosis factor-a) induced by Influenza A virus (PR8/H1N1) in MDCK cells
Microbiology and Infectious DiseasesInfluenza A virus (IAV) can cause acute respiratory distress syndrome, which leading to kill 250000 to 500000 of world ...Read more
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Antibacterial properties of saffron
Microbiology and Infectious DiseasesSaffron is a small herb of the Welsh family. This is a plant with spherical onions which surrounded by a brown membrane....Read more
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Anti-anxiety effects of sinapic acid in NMRI mice
Nutrition and HealthThe present study investigated the anxiolytic effects of sinapic acid on NMRI mice behavior in the elevated plus-maze (E...Read more
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Investigating the antitumor activity of PNU-74654 as Wnt/β-catenin inhibitor, alone or in combination with gemcitabine in MiaPaCa-2 pancreatic cancer cell
Cancer; Prevention, Diagnosis and TreatmentWnt/beta-catenin pathway is one of the key dysregulated pathways in several malignancies, including pancreatic cancer (P...Read more
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A foundation for universal T-cell based adoptive immunotherapy
Cancer; Prevention, Diagnosis and TreatmentThe patient-specific autologous therapy could be a significant limiting factor in the large-scale exploitation of CAR te...Read more
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Influence of matrix rigidity on the differentiation of mesenchymal stem cells in response to TGF-β
Stem cell and Medical ApplicationsBone marrow human mesenchymal stem cells (hMSCs) are an appreciated cell source for tissue engineering and regenerative ...Read more
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Kisspeptin decreases mean serum adiponectin concentrations in rats
Women and Reproductive HealthKisspeptin/GPR54 signaling system is one of the most important pathways of hypothalamus for regulating reproductive proc...Read more
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Gene Editing: As a new treatment for HIV
Medical GeneticsCurrent treatments in HIV treatment don’t eliminate the low level of viral replication in latently infected cells, whi...Read more
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Epigenetic Mechanisms as Therapeutic Targets
Medical GeneticsEpigenetics, in conjunction with genetic mechanisms, determine the biological fate of cells and living organisms. epig...Read more
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Managing The Abnormal Papsmear In Pregnancy
Cancer; Prevention, Diagnosis and TreatmentCervical cancer is the most common malignancy diagnosed during pregnancy . The incidence of abnormal pap smear in pregna...Read more
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The effect of 5μM benzoquinone JAG1 and Wnt5a genes in mesenchymal stem cells(MSCs) found in bone marrow(BM) niche
Stem cell and Medical ApplicationsBenzoquinone(BQ) is one of benzene metabolite after entering body, its prolonged presence in body leads to blood disorde...Read more
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Some candidate Biomaterials for Amniotic Membranes (AM) Regeneration: a review
Stem cell and Medical ApplicationsAmniotic Membranes (AM) wich form the amniotic sac filled by amniotic fluid and completely surrounds the embryo/fetus. I...Read more
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An investigation on the structure and function of the cell surface lung-specific antigens for development a new generation of immunotoxins
Cancer; Prevention, Diagnosis and TreatmentLung cancer, with common symptoms such as coughing, weight loss and shortness of breath, is a disease via uncontrolled g...Read more
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Antimicrobial susceptibility of Acinetobacter baumannii isolated from different clinical samples in hospitalized patients
Microbiology and Infectious DiseasesAcinetobacter baumannii is a gram negative bacteria, which is cause multidrug-resistant nosocomial infection. Control an...Read more
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The Study of the Requested Antibiotics during Each Patient’s confining to Bed in Namazi 1000 beds hospital, May 22nd to July 21st
Microbiology and Infectious DiseasesOccurring resistive microbial trends is one of basic obstacles in infection disease treatments. Prescribing too much ant...Read more
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isolates from Kermanshah province submitted at National Animal tuberculosis reference Laboratory at Razi institute
Microbiology and Infectious DiseasesTuberculosis is a zoonotic which has long been recognized and is still one of the most life-threatening diseases. Tuberc...Read more
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Berberine induced cell death of human colon cancer HT-29 through mediating of PARP
Cancer; Prevention, Diagnosis and TreatmentBerberine is an isoquinoline which has many various pharmacological activities, including anticancer activities. Poly (A...Read more
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Discrimination of Leishmania species by Arginine permease gene AAP3as a suitable molecular tool for detection and genetic proximity analysis
Microbiology and Infectious DiseasesLeishmaniasis presents itself in different clinical manifestations such as: visceral Leishmaniasis, Cutaneous Leishmania...Read more
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Finding a new approach for Treatment of osteoporosis with trace element and antioxidant in rat animal model
Metabolism and Metabolic DiseasesOne of the most common bone metabolic and endocrinal disorders is osteoporosis. It is defined by progressive bone loss, ...Read more
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Anti-clostridial role of probiotics in prevention and treatment of Clostridium difficile infections
Microbiology and Infectious DiseasesPatients with varied conditions, such as Antibacterial therapy, Cancer chemotherapy, and gastrointestinal surgery are at...Read more
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MUC21 as a suitable candidate for immunotoxins development for targeting esophageal cancer
Cancer; Prevention, Diagnosis and TreatmentEsophageal cancer is the world's eighth most common cancer and the sixth most common cause of cancer death in the world....Read more
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Molecular screening for E255K mutations in Imatinib Resistant-CML
Medical GeneticsChronic myelogenous leukemia (CML) is a clonal disease that kind of hematopoietic stem-cell cancer. A significant number...Read more
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Study of properties of Juglans regia plant on women’s health
Women and Reproductive HealthJuglans regia plant is one of Iranian native plants that some of it’s productive types are in Markazi province. The b...Read more
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Braest cancer micrometastatic detection in sentinele lymph nodes using molecular marker
Cancer; Prevention, Diagnosis and TreatmentBreast cancer is prevalent malignancy among women in worldwide (1). Molecular diagnosis is recently proposed as a sensit...Read more
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Normal body mass index as a protective factor for osteoporosis after menopause
Nutrition and HealthIncreased body weight is positively related to higher bone mineral density (BMD) in both pre- and post-menopausal women....Read more
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The association of the H19 rs217727 polymorphism and Preeclampsia
Medical GeneticsPre-eclampsia is a pregnancy specific disorder; which is defined as pregnancy-induced hypertension and proteinuria. H19 ...Read more
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Cytotoxicity study of nanoparticles containing aminoglycosides
Nano-Biotech MedicalAminoglycosides are a bunch of antibiotics that inhibit the synthesis of protein in bacteria and lead to eradication of ...Read more
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Molecular diagnosis of Mycoplasma spp. arthritis by PCR
Microbiology and Infectious DiseasesArthritis is one of the most common inflammatory diseases. It is characterized by symptoms such as systemic inflammation...Read more
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Molecular identification of Aspergillus isolated from livestock feed and poultry using ASAP1 sequencing
Microbiology and Infectious DiseasesThe contamination of livestock feed and poultry with toxic fungi, such as aspergillus in the air and the environment, is...Read more
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Application of stem cells in modern therapeutic methods
Stem cell and Medical ApplicationsStem cells are one of the modern therapies being used over recent years to treat diseases such as repairing damaged hear...Read more
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Investigation of toxicity effect of 4-Mepgc and 4-No2pgc on the K562 cell line (chronic myeloid leukaemia)
Cancer; Prevention, Diagnosis and TreatmentLeukemia is a particular type of cancer characterized by the failure of cell death or disability in the differentiation ...Read more
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Evahuation of Serum Cholesterol as a Component Of Metabolic Syndrome in the Cord Blood of Mothers With Polycystic Ovary Syndrome
Women and Reproductive HealthPolycystic ovary syndrome is one of the most common endocrine disorder among women of reproductive age is the prevalence...Read more
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Molecular mechanism of alpha-2 adrenergic receptors in locus Coeruleus
Medical GeneticsPain is one of the most common forms of psychological stress and the most common phenomenon in medical science. Analgesi...Read more
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Evaluation of Interleukin 10 Gene Promoter Polymorphisms of -592A/C and -1082A/G Region Among Obese Individuals with Type 2 Diabetes in Alborz Province
Metabolism and Metabolic DiseasesToday diabetes is one of the most prevalent noncontagious diseases around the world. There is strong evidence showing in...Read more
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Toxic effects of Selenite and need to bio removal of it
Nutrition and HealthSelenium is an important micronutrient for human and animal health, however it is toxic slightly above homeostatic requi...Read more
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Human reovirus destroys liver cancer cell line (Huh-7)
Cancer; Prevention, Diagnosis and TreatmentThe Huh-7 cell line was derived from a liver tumor in a 57-year-old Japanese male patient in 1982. Hepatocellular carcin...Read more
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In silico evaluation of anti-retroviral effects of lactoferrin from different species
Microbiology and Infectious DiseasesLactoferrin (LF) is an iron binding glycoprotein that is present in body fluids and mucosal secretions. Antimicrobial pr...Read more
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Design, modeling and simulation of a novel immunotoxin structure affective against gastrointestinal malignancies
Cancer; Prevention, Diagnosis and TreatmentGastrointestinal malignancies comprise a remarkable proportion of cancer deaths each year. Although many drugs have been...Read more
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The Bioinformatic prediction of selected miRNAs role in regulation of cell death pathways in Parkinson’s disease
Medical GeneticsParkinson's disease (PD) is the second most common neurodegenerative disease. Due to its unknown etiology and pathology,...Read more
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the review of The implications in toxicity Metabolomics of Delta9-tetrahydrocannabinol
Metabolism and Metabolic DiseasesThe plant Cannabis sativa has been used for the effects of its psychoactive resins that name is (cannabinoid δ-9-tetrah...Read more
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Microfluidic 3D cell-Culture platforms for drug response monitoring: potential applications for individualized cancer treatment
Cancer; Prevention, Diagnosis and TreatmentIndividualized monitoring of drug response is supposed as a main constituent of personalized treatment. Current methods ...Read more
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A technical overview on the neuronal dysfunction induced by heat stroke on the C57 mice models
Medical GeneticsHeat is an environmental hazard that via increasing core body temperature leads to innate stress with pathological and p...Read more
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evaluation of anti-mullerian hormone in daughters of women with polycystic ovary syndrome
Women and Reproductive HealthPolycystic Ovary Syndrome(pcos) is one of the most common endocrine diseases among women during their fertility years . ...Read more
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The comparative proteomic pattern study of albumin fraction in type I Gaucher Patients with 2 Dimensional Electrophoresis
Metabolism and Metabolic DiseasesThe gaucher disease is the most common type of lysosomal storage diseases that, particularly affects the macrophage cell...Read more
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Evaluation of selenium & zinc levels and antioxidant power in serum of women with endometriosis before and after administration of N-Acetylcysteine
Women and Reproductive HealthEndometriosis is characterized by the presence of glands and endometrial stroma outside the uterine and affects approxim...Read more
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Impact of CYP3A5 and CYP3A4 genetic polymorphisms on susceptibility risk of chronic myeloid leukemia and treatment response
Medical GeneticsCYP3A5 and CYP3A4 are the members of the CYP3A gene family which metabolizes 50% of therapeutic drugs and steroid hormon...Read more
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The evaluation of recombinant beclin1 effect on cervical cancer in mice model
Medical GeneticsOne of the factors that play a direct role in suppressing cancer cells is the pathway of autophagy and apoptosis that is...Read more
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In silico cancer therapy by using genome editing tool: CRISPR/Cas9
Cancer; Prevention, Diagnosis and TreatmentGiven the fact that cancer today has a broad spectrum of diseases in the populations, and also by relying on the fact th...Read more
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Differentiation of mesenchymal stem cells to insulin-producing cells with of use to basic culture medium
Metabolism and Metabolic DiseasesDiabetes mellitus type 1 is a form of diabetes mellitus in which not enough insulin is produced. To this date, no defini...Read more
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Investigation of antioxidant capacity of silver nanoparticles with Laurencia caspica seaweed on liver cancer cell line (HepG2)
Nano-Biotech MedicalHepatocellular carcinoma is a type of hepatocellular carcinoma that occurs most often in cases of hepatitis B and C, or ...Read more
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The relationship between serum creatinine and creatinine clearance with the occurrence and severity of coronary artery disease
Metabolism and Metabolic DiseasesCardiovascular diseases are thought to be the most important reason of mortality around the world. Among them coronary a...Read more
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Food Patterns and Framingham Risk Score in Iranian Adults: Tehran Lipid and Glucose Study: 2005-2011
Nutrition and HealthHealthy dietary habits can prevent cardiovascular diseases (CVD). The aim of the present study was to investigate the as...Read more
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Bioinformatics evaluation of hsa-miR-548g related to single nucleotide polymorphism (rs1803622) of GAPDH gene in patients suffering from breast cancer
Cancer; Prevention, Diagnosis and TreatmentBreast cancer is one of the most prevailing cancer among females. GAPDH gene is located on chromosome l on position of G...Read more
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Expression of CD74 in Ovarian cancer
Medical GeneticsOvarian cancer is a cancer that forms in or on an ovary. The pro-inflammatory cytokine migration inhibitory factor (MIF)...Read more
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Molecular monitoring of Chronic Myeloid Leukemia in Chronic Phase (CML-CP)
Medical GeneticsQuantification of the BCR-ABL transcript is recommended to follow-up CML patients that treated by Imatinib mesylate (IM)...Read more
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Association of umbilical coiling index with hypothyroidism and gestational diabetes mellitus.
Metabolism and Metabolic DiseasesGestational diabetes mellitus [GDM] and hypothyroidism are prevalent and potentially serious condition which may put mot...Read more
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Study of gene expression network in varicose veins disease by microarray expression analysis
Medical GeneticsThere is a strong body of circumstantial evidence which implicates genetics in the etiology and pathology of and venous ...Read more
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Experimental and theoretical investigation on Mandelic acid (R, S) enantioselective separation using Vancomycin chiral column in high performance liquid chromatography
Nano-Biotech MedicalNowadays, antibiotic chiral columns can be used in various chromatography separations. The high potential of these compo...Read more
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Preparation and characterization of Nanofibers Using an Electrospinning Technique as ocular drug delivery
Nano-Biotech MedicalFor the treatment of anterior eye segment infections using anti-infective agents, topical ocular application is the most...Read more
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Effect of genistein associated with agonist (17-β estradiol) on the viability and apoptosis of human hepatocellular carcinoma HepG2 cell line
Cancer; Prevention, Diagnosis and TreatmentBackground: One of the most lethal cancers is Hepatocellular carcinoma (HCC). Genistein (GE) is a choice compound for tr...Read more
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Evaluation of gonadotropin hormones in non-obstructive azoospermia patients
Women and Reproductive HealthInfertility refers to the inability of couples to achieve a successful pregnancy after a year of sexual intercourse with...Read more
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The Evaluation of Methicillin Resistant Staphylococcus aureus (MRSA) Colonization on Skin Lesions in Patients with Psoriasis
Microbiology and Infectious DiseasesPsoriasis is a chronic and inflammatory disease of the skin. Recently, the role of microbial agents in the development o...Read more
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Blocking of vascular endothelial growth factor signaling through design of bi-specific single domain antibody
Nano-Biotech MedicalOver-expression of vascular endothelial growth factor (VEGF) leads to the proliferation and neovasculature of cancer cel...Read more
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Rapid and cost effective method for the purification of DNA from Streptococcus mutans and other oral microorganisms
Microbiology and Infectious DiseasesOver 325 bacterial species have been cultured from dental plaque. Not all species can be cultured routinely. Thus, consi...Read more
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An update review about stem cell therapy for diabetes mellitus
Stem cell and Medical ApplicationsMesenchymal stem cells (MSCs) are the most widely used stem cells of the human body because of successful isolation, and...Read more
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Cloning, expression and functional assay of bacterial Uricase, a medical enzyme for the treatment of chronic gout
Metabolism and Metabolic DiseasesUricase, which is originated from a variety of organisms including bacteria, is an important agent for tracing of Uric A...Read more
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The role of cabergoline medicine in treating Cushing's syndrome: A systematic review
Metabolism and Metabolic DiseasesCushing's syndrome is an endocrine disorder caused by the excessive production of corticosteroid hormones and adrenocort...Read more
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Enrichment analysis of hsa-miR-320b-1 most related pathways in cancer
Cancer; Prevention, Diagnosis and TreatmentIntroduction: Cancer is a complex disease in which the expression of the gene is unbalanced. MicroRNAs are a group of no...Read more
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Serum levels of testosterone, dehydroupiandrosterone sulfate, luteinizing hormone and follicular stimulus hormones in offspring of women with polycystic ovary syndrome
Women and Reproductive HealthPolycystic Ovary Syndrome(pcos) is one of the most common endocrine diseases among women during their fertility years . ...Read more
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Function of Diabetes Mellitus on the Body, Diagnosis until Treatment
Medical GeneticsDiabetes mellitus is a metabolic pathway in which the insulin hormone is secreted or incompletely secreted; it is a meta...Read more
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Triplet repeats in Androgen receptor and it's relation with cardiovascular disease
Medical GeneticsCardiovascular disease is one of the main cause of death in all around the world and researches indicated that in United...Read more
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The salivary beta-2microglobulin (β2M) and prostate-specific antigen (PSA) can be used as an alternative to the serum β2M and PSA for diagnosis and monitoring of prostate diseases
Cancer; Prevention, Diagnosis and TreatmentIn recent years, the use of saliva as a specimen, due to its non-invasive and easy access increased. But their roles hav...Read more
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Investigation the effect of low intensity pulsed ultrasound (LIPUS) on proliferation of G 292 osteosarcoma cells on 3D porous PLGA/β-TCP scaffold within perfusion bioreactor
Stem cell and Medical ApplicationsInvestigation the effect of low intensity pulsed ultrasound (LIPUS) on proliferation of G 292 osteosarcoma cells on 3D p...Read more
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Identifying MicroRNA-mRNA regulatory network in breast cancer sample with drug resistance
Cancer; Prevention, Diagnosis and TreatmentA computational approach to prediction of miRNA targets narrowing down potential target sites for experimental validatio...Read more
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Current Advances in the Genetic Basis of Rheumatoid Arthritis
Medical GeneticsRheumatoid arthritis (RA) is a chronic inflammatory disease characterized by a distinctive pattern of joint involvement ...Read more
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Effect of Biochanin A on retinal angiogenesis and inflammation in STZ induced diabetic rats
Metabolism and Metabolic DiseasesWithout proper medication for the treatment of diabetic retinopathy (DR), retinal cells become malnourished and degenera...Read more