Biomedicine Congress - Biology Congress - Medicine Congress

Mahdieh Salimi*

National Institude of Genetic Engineering and Biotechnology
Tehran, Tehran

Abstracts, [Author]

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• Prevalence of septicemia in Intasive care unit and Internal medicine wards patients in Rajaee Hospital of Karaj

  Microbiology and Infectious Diseases

  Septicemia or blood infections is One of the most important causes of death in patients hospitalized in different parts...Read more

• Comparison of antimicrobial activity of hydroalcoholic extract of fig(Ficus carica) against Staphylococcus aureus(MSSA & MRSA) with some antibacterial drugs

  Microbiology and Infectious Diseases

  Staphylococcus aureus is one of the five most common causes of hospital infections and death the worldwide. The excessiv...Read more

• Removal of Nickel (II) From Drinking Water Using Thiol-Functionalized Chitosan

  Nano-Biotech Medical

  Some heavy metals are the causes of various diseases among humans. Thus, removing heavy metals is necessary in order to ...Read more

• Investigating the absorption of anti-cancer drugs on the surface of the boron nitride nano cage by the dense function theory

  Nano-Biotech Medical

  magesterol is a drug used in the treatment of breast and endometrial cancer. Due to the unwanted side effects of this dr...Read more

• Down regulation of Bcl2 and up regulation of Bax during 2-NDC mediated apoptosis in Acute Promyelocytic Leukemia NB4 cells

  Cancer; Prevention, Diagnosis and Treatment

  Dithiocarbamates have been known as important chemical synthetic compounds for treatment of cancer....Read more

• An investigation on the structure and function of the cell surface breast-specific antigens for development a new generation of immunotoxins

  Cancer; Prevention, Diagnosis and Treatment

  Breast cancer with heterogeneous features in morphology, clinic, and responses to therapeutic options, is one of the mos...Read more

• Dietary intake of antioxidants in elderly: A case-control study in Iran

  Nutrition and Health

  Nutrient deficiencies such as antioxidants are common problems in elderly subjects which can result in different cancers...Read more

• Potentiation of mitomycin C-induced apoptosis by lithium chloride in MDA-MB-231 breast cancer cells

  Cancer; Prevention, Diagnosis and Treatment

  Breast cancer is the principle cause of cancer mortality in females. Mitomycin C (MMC), as a potent antitumor drug, is u...Read more

• Evaluating Anticancer Effects of Tamarix ramosissima on A549 Cells

  Cancer; Prevention, Diagnosis and Treatment

  Lung cancer is the leading cause of cancer death all over the world. Using plant derived materials as folk remedy has be...Read more

• Antiangiogenic Effect of Endostatin-derived Peptides on a Mouse Model of Colon Cancer

  Cancer; Prevention, Diagnosis and Treatment

  Colon Cancer is among the most common malignancies worldwide. Angiogenesis is the formation of new microvasculature thro...Read more

• Frequency of [aac(6’)-Ie-aph(2”)] gene and aminoglycosids drug resistance in clinical Staphylococcus aureus isolates by two phenotype and molecular methods

  Microbiology and Infectious Diseases

  Staphylococcus aureus is one of the most common bacterial infection, these bacteria are an agent of nosocomial and commu...Read more

• Development and implementation of a novel panel consisting 16 STR markers linked to the HLA-gene-cluster applicable for HLA-typing, PND&PGD

  Medical Genetics

  PGD (Pre-implantation Genetic Diagnosis) in combination with human leukocyte antigen (HLA) matching, allow not only sele...Read more

• BsmI (rs1544410) polymorphism of vitamin D receptor gene modulates improvement of vitamin D status in overweight women with hypovitaminosis D

  Nutrition and Health

  The aim of the present study was to evaluate the possible influence of BsmI (rs1544410) polymorphism of vitamin D recept...Read more

• Review: ASD heritability

  Medical Genetics

  Autism Spectrum Disorder (ASD) is one of the most common neurodevelopmental disorders; due to its high occurrence rate a...Read more

• Crispr/cas9 a New Approach to Genome Engineering

  Medical Genetics

  In 1987, scientists found an acquired immune system in E.coli genome, included series of short repetitive interspaced pa...Read more

• The antiproliferative and cell cycle arrest effects of Botox on MCF-7and PC-3 cell line

  Cancer; Prevention, Diagnosis and Treatment

  Botulinum toxin (Botox) is the most potent biological toxin known to against human life. It can be used as a selective a...Read more

• Investigating the relationship between metacognitive beliefs, and premenstrual syndrome and depression caused by that, in female students studying at Tehran University of Medical Sciences

  Women and Reproductive Health

  The purpose of this research was studying the relation between meta-cognitive beliefs on premenstrual syndrome and depre...Read more

• Effect of Biochanin A on retinal angiogenesis and inflammation in STZ induced diabetic rats

  Metabolism and Metabolic Diseases

  Without proper medication for the treatment of diabetic retinopathy (DR), retinal cells become malnourished and degenera...Read more

• Lack of association between Hypoxia Inducible Factor rs11549465 polymorphism and Preeclampsia

  Medical Genetics

  Pre-eclampsia (PE) is an obstetric disorder that may result inmaternal and neonatal mortality and morbidity. Placental h...Read more

• Synthesis of pH-sensitive micelles based on F127-Dox conjugated for drug delivery to cancer cells

  Nano-Biotech Medical

  A variety of nano-systems constituted by polymer–drug conjugates have been designed to overcome its shortages on water...Read more

• Computational analysis and design of crRNA for post transcriptional regulation of metastamiR-10b and metastamiR-126 by CRISPR-C2C2 technique.

  Medical Genetics

  One of the important causes of death in cancer patients is metastasis. Recently have been shown that specific group of m...Read more

• The role of nutrition in gestational diabetes

  Women and Reproductive Health

  Gestational diabetes is a condition in which blood glucose levels are rising during pregnancy and diabetes symptoms in a...Read more

• THE TOLE OF PROBIOTICS IN PUBLIC HEALTH

  Nutrition and Health

  In the last decade, we have seen dramatic changes in understanding the role of foods in improving human health. scientif...Read more

• Assessment of Tuberculous arthritis using molecular technique

  Microbiology and Infectious Diseases

  Bacterial arthritis is one of the arthritis diseases known that can rapidly cause joint damage. Among the bacteria caus...Read more

• Anti-inflammatory activity of Caspian Cobra (Naja naja oxiana) snake Venom in EAE model of MS

  Medical Genetics

  Multiple sclerosis (MS) is a chronic neuroinflammatory demyelinating disorder of the Central Nervous System (CNS) with a...Read more

• Evaluation of magnesium & copper levels and antioxidant power in serum of women with endometriosis before and after administration of N-acetylcysteine

  Women and Reproductive Health

  Endometriosis is caused by the presence of ectopic endometrial stromal outside the endometrial cavity. The oxidative str...Read more

• Pattern of efflux pump genes in imipenem resistant Acinetobacter isolates

  Microbiology and Infectious Diseases

  Acinetobacter species are opportunistic pathogens and responsible for various types of nosocomial infections. They are i...Read more

• Reproductive Health Training Program on Students in IRAN: An Action Research Approach

  Women and Reproductive Health

  Transition from adolescence to adulthood is one of the important periods in the individual life. New behaviors are learn...Read more

• Studying the relation of blood lead level with the thyroid hormones and blood factors

  Metabolism and Metabolic Diseases

  Lead has many applications in the industry but does not play a specific physiological role in the body. According to per...Read more

• The Possible Role of B. thetaiotaomicron-derived Outer Membrane Vesicles (OMVs) in the Modulation of Cholesterol Uptake and Diet-induced Obesity

  Metabolism and Metabolic Diseases

  Altered gut microbiota composition has been proven to be associated with several disorders including metabolic syndrome....Read more

• COMPARATIVE STUDY OF OLERACEIN E AND OLERACEIN L EFFECTS ON ANTI OXIDANT ACTIVITY, ANTI DIABETIC INDICATORS AND DAMAGE BIOMARKERS LEVELS IN PANCREATIC CELL LINE

  Nutrition and Health

  The medicinal plants have valuable biochemical effects. The aim of this study was to assess the effects of Oleracein E a...Read more

• Higher efficacious delivery in non-toxic dose of Genistein to AML cells by its conjugation on Superparamagnetic Fe3O4 Nanoparticles decorated with bio-compatible Carboxymethylated Chitosan

  Nano-Biotech Medical

  Genistein is an isoflavone with anti-cancer properties, but effective dosage against malignant cells was not in non-toxi...Read more

• Evaluation of gonadotropin hormones in non-obstructive azoospermia patients

  Women and Reproductive Health

  Infertility refers to the inability of couples to achieve a successful pregnancy after a year of sexual intercourse with...Read more

• Production of protein A containing Thiol Group for binding to fluorescence dye To increase the sensitivity of antibody detection

  Nano-Biotech Medical

  staphylococcal Protein A is a cell wall component which has the ability to bind to immunoglobulins of different animal s...Read more

• Evaluation of Interleukin 10 Gene Promoter Polymorphisms of -592A/C and -1082A/G Region Among Obese Individuals with Type 2 Diabetes in Alborz Province

  Metabolism and Metabolic Diseases

  Today diabetes is one of the most prevalent noncontagious diseases around the world. There is strong evidence showing in...Read more

• Benefical Effects of hydroalcoholic extract of fenugreek seeds on some Biochemical factors and oxidative stress in high-fructose diet-induced metabolic syndrome in rats

  Metabolism and Metabolic Diseases

  Background: Fenugreek (Trigonella foenum graecum) is a traditional herbal plant. seeds of Fenugreek have several propert...Read more

• Correlation of umbilical coiling index and HbA1C in gestational diabetes mellitus (one-step strategy).

  Metabolism and Metabolic Diseases

  Gestational diabetes mellitus [GDM] is a prevalent and potentially serious condition which may put mothers and fetuses a...Read more

• Identifying MicroRNA-mRNA regulatory network in breast cancer sample with drug resistance

  Cancer; Prevention, Diagnosis and Treatment

  A computational approach to prediction of miRNA targets narrowing down potential target sites for experimental validatio...Read more

• isolates from Kermanshah province submitted at National Animal tuberculosis reference Laboratory at Razi institute

  Microbiology and Infectious Diseases

  Tuberculosis is a zoonotic which has long been recognized and is still one of the most life-threatening diseases. Tuberc...Read more

• The role of cabergoline medicine in treating Cushing's syndrome: A systematic review

  Metabolism and Metabolic Diseases

  Cushing's syndrome is an endocrine disorder caused by the excessive production of corticosteroid hormones and adrenocort...Read more

• Identification of Oral strains of Lactobacillus.species in patients with chronic periodontitis and healthy individuals

  Microbiology and Infectious Diseases

  Oral infections constitute some of the most common and costly forms of infections in humans.Chronic periodontitis has be...Read more

• The effects of anticancer of 7-hydroxycoumarine on the colon cancer cell line (HT29) and the normal mouse fibroblast cells (L929)

  Cancer; Prevention, Diagnosis and Treatment

  Colorectal cancer it is a lethal and common cancer. due to the development of drug resistance to chemical drugs, the ne...Read more

• Impact of CYP3A5 and CYP3A4 genetic polymorphisms on susceptibility risk of chronic myeloid leukemia and treatment response

  Medical Genetics

  CYP3A5 and CYP3A4 are the members of the CYP3A gene family which metabolizes 50% of therapeutic drugs and steroid hormon...Read more

• Survey of Changes gene expression levels of SAP 1-3 Candida albicans samples treated with treated with Fluconazole-loaded PLGA Nanospheres, in comparsion with drug Fluconazole

  Microbiology and Infectious Diseases

  Secreted Aspartyl Proteinase (SAP) is one of the main virulent factors in the pathogenesis of Candida. This enzyme is en...Read more

• Effects of Rosmarinic acid on oxidative stress and total antioxidant capacity in vivo study

  Metabolism and Metabolic Diseases

  Diabetic disease is characterized by chronic hyperglycaemia. Numerous studies have shown that in diabetes mellitus, ther...Read more

• A review: Runt-related transcription factor 2 (RUNX2) and its signaling pathways in cardiovascular complications.

  Metabolism and Metabolic Diseases

  Vascular calcification (VC) is a process similar to bone mineralization. VC has been observed in chronic kidney disease,...Read more

• Differentiation of mesenchymal stem cells to insulin-producing cells with of use to basic culture medium

  Metabolism and Metabolic Diseases

  Diabetes mellitus type 1 is a form of diabetes mellitus in which not enough insulin is produced. To this date, no defini...Read more

• Green synthesis of Gold nanoparticles by water extract of common nettle leaves

  Nano-Biotech Medical

  Gold nano particles (AuNPs) are being considered for cancer treatments for targeted drug delivery in pharmacology and me...Read more

• Self-Concept among Infertile women receiving oocyte donation and Fertile Women

  Women and Reproductive Health

  One of the technologies used to assist fertility is oocyte donation. Although there is sufficient information about med...Read more

• Evaluation of Acholeplasma laidlawii in biologic products by PCR method

  Microbiology and Infectious Diseases

  Contamination of biological products and cell cultures is one of the important problems in producing a good and safe pro...Read more

• Endurance training resulted in significantly greater betatrophin responses compared with resistance training alone, and resistance and endurance exercises combined

  Metabolism and Metabolic Diseases

  Betatrophin, which recently identified, is a liver and adipose tissue produced hormones that regulates the level of lipi...Read more

• Efficacy of Bone Marrow Mesenchymal Stem Cells and an Amniotic Membrane on the Number of Mast Cells and Degranulation in Random Skin Flaps in Rats

  Stem cell and Medical Applications

  Skin flap procedures are usually used in plastic surgery. Failing can follow, lead to the necrosis of the flap. Therefor...Read more

• Evaluation of the effect of saturated and unsaturated fatty acids on the growth and production of outer membrane vesicles in human gut microbiota

  Microbiology and Infectious Diseases

  A diverse and complex symbiotic microbial community colonize in human host,espicially in the gastrointestinal tract,refe...Read more

• Preparation and assessment of chitosan-polyethylenimine-carboxymethyl dextran nanoparticles for efficient siRNA delivery in vitro

  Nano-Biotech Medical

  Among polycation nanoparticles, chitosan nanoparticles (Ch) have emerged as promising carriers for gene delivery, nevert...Read more

• Nephroprotective effect of Lavandula officinalis L. ethanolic extract in alloxan induced diabetic rats

  Nutrition and Health

  Diabetes mellitus (DM), a metabolic disorder is a major public health problem in both developed and developing countries...Read more

• Evaluation of antioxidant activity and cytotoxicity of an ethanol extract of leaves, fruits and calyx of Physalis alkekengi on human lung cancer A549 cell line

  Cancer; Prevention, Diagnosis and Treatment

  Lung cancer is the most common cancers and chemotherapy cancer treatment is one of the methods, but because of the lack ...Read more

• Enrichment analysis of hsa-miR-320b-1 most related pathways in cancer

  Cancer; Prevention, Diagnosis and Treatment

  Introduction: Cancer is a complex disease in which the expression of the gene is unbalanced. MicroRNAs are a group of no...Read more

• Investigation efflux pump -activated fluoroquinolone resistance in pseudomonas aeroginosa multi drug resistance isolates by CCCP inhibitor

  Microbiology and Infectious Diseases

  Pseudomonas aeruginosa is the third cause of nosocomial infections after Staphylococcus aureus and E. coli .One of the p...Read more

• The Anticancer Effect of Plant Aqueous Extracts of Aloe Vera in Gene Expression Bax and Bcl-2 on Gastric Adenocarcinoma AGS Cells

  Cancer; Prevention, Diagnosis and Treatment

  Gastric cancer is a major cause of cancer death. In terms of incidence is the fourth most common cancer and the second l...Read more

• TYCSB culture media reliability for S. mutans isolation

  Microbiology and Infectious Diseases

  Although the clinical significance of dental caries is well recognized, the exact etiology of the condition is not under...Read more

• The impact of the vaginal probiotic lactobacillus on the prevention and treatment of cervical cancer

  Cancer; Prevention, Diagnosis and Treatment

  Today, cervical cancer is the second most common cancer after breast cancer among women and it`s considered dangerous ...Read more

• Effect of Valproic Acid on Proliferation and Apoptosis of Colon Cancer HT 29 Cell Line

  Cancer; Prevention, Diagnosis and Treatment

  The structure of chromatin is made up of DNA, histones, and non-histone proteins with the basic repeating unit, nucleoso...Read more

• Evaluation of the HLA-B07 Allelic frequency in the patients with spondyloarthritis syndrome in zanjan province

  Medical Genetics

  In 1974 Moll and colleagues established the concept of a group of inter-related disorders originally termed seronegative...Read more

• Kidney Cancer, Cancer without Early Symptoms

  Cancer; Prevention, Diagnosis and Treatment

  The kidneys are a pair of organs in the human body that are located on either side of the spine and in the lower abdomen...Read more

• The association between pre-gravid BMI with fasting glucose and lipid profile in gestational diabetes following Assisted Reproduction.

  Women and Reproductive Health

  Gestational diabetes mellitus (GDM) is one of the most endocrine pregnancy outcomes. High prevalence of GDM was reported...Read more

• Function of Diabetes Mellitus on the Body, Diagnosis until Treatment

  Medical Genetics

  Diabetes mellitus is a metabolic pathway in which the insulin hormone is secreted or incompletely secreted; it is a meta...Read more

• Effect of Praziquantel Drug on Prevention of Afflicting Dogs with Cestode Echinococcus Granulosus

  Microbiology and Infectious Diseases

  Awareness of the impact range of praziquantel drug on prevention of afflicting dogs with echinococcus granulosus parasit...Read more

• Mediterranean dietary pattern adherence modify the association between FTO genetic variations and obesity phenotypes

  Nutrition and Health

  There is an increasing interest in examining whether dietary patterns modify the association of fat mass and obesity ass...Read more

• Evaluation of cytotoxicity, viability and induced oxidative stress by Nickel (II) complex of thiosemicarbazone

  Cancer; Prevention, Diagnosis and Treatment

  Thiosemicarbazones and their metal complexes have significant biological activities including anticancer, antibacterial,...Read more

• personalized medicine in oncology

  Medical Genetics

  The term peronalized medicine is used for the identification of optimal drug type and optimal drug dosage for individual...Read more

• Surface modification of Chitosan nano-fiber by cold atmospheric plasma

  Nano-Biotech Medical

  Surface modification is the act of modifying the surface of a material by bringing physical, chemical or biological char...Read more

• Cloning of Human THAP11 Gene in Lentiviral Vector

  Stem cell and Medical Applications

  Thap11, the most recent described member of THAP domain family, which is in volved in cell proliferation and described a...Read more

• A study on the interaction of angiotensin I converting enzyme inhibitory peptide with human hemoglobin protein by conductometry method in the absence and presence of a low frequency electromagnetic fi

  Metabolism and Metabolic Diseases

  High blood pressure, or hypertension, is a chronic disease in which the blood pressure goes up. Angiotensin converting e...Read more

• Comprehensive databank of Iranian patients with Noonan syndrome

  Medical Genetics

  Noonan syndrome (NS) (OMIM 163950) considered as a relatively common (1/1000-2500), developmental, multi-organ and compl...Read more

• Mortality effect of Silibinin on the A549 cell line

  Cancer; Prevention, Diagnosis and Treatment

  Lung cancer is the leading cause of cancer death in the world, with 1,375,000 deaths annually. Common chemotherapy such ...Read more

• Design, modeling and simulation of a novel immunotoxin structure affective against gastrointestinal malignancies

  Cancer; Prevention, Diagnosis and Treatment

  Gastrointestinal malignancies comprise a remarkable proportion of cancer deaths each year. Although many drugs have been...Read more

• Toll-like receptor 4 mediates cross-talk between peroxisome proliferator-activated receptor γ and nuclear factor-κB in mouse melanoma (B16F10) in vitro

  Cancer; Prevention, Diagnosis and Treatment

  There is increasing evidence that chronic activation of nuclear factor-κB (NF-κB), which is an essential signaling pat...Read more

• Study genetic susceptibility polymorphisms for chronic lymphocytic leukemia in Iranian population.

  Medical Genetics

  Chronic lymphoid leukemia (CLL) is the most common form of leukemia found in adults. CLL is a monoclonal disorder that w...Read more

• Role of NBD and DBD in P- glycoproteinfunction, a Molecular dynamic simulation

  Cancer; Prevention, Diagnosis and Treatment

  P-glycoprotein (P-gp) is an ATP-binding cassette (ABC) transporter which belongs to multidrug resistance pump super fami...Read more

• Operational study of plastination as an alternate method for dissection

  Nano-Biotech Medical

  Since, two-thirds of the approved Zoology Laboratory syllables, defined by the Ministry of Science, Research and Technol...Read more

• Perineal massage during pregnancy and perineal safety during childbirth

  Women and Reproductive Health

  Introduction: Women frequently suffer from perineal trauma during childbirth, especially during the first childbirth. ...Read more

• Effect of folic acid supplementation on acute effects of trimethoprim/sulfamethoxazole on histopathological changes in the testes of adult male rats

  Stem cell and Medical Applications

  Male infertility has been reported following long-term sulfasalazine use for ulcerative colitis treatment. However, the ...Read more

• Effect of marjoram extract on sperm concentration and its survival percentage in oxidative-cadmium stress in adult male rats

  Nutrition and Health

  Nutrition Safety and Health is one of the important factors in fertility.Cadmium as an environmental pollutant by free r...Read more

• The giant lipoma pediculated in the falciform ligament: a case report

  Cancer; Prevention, Diagnosis and Treatment

  Introduction: Lipoma is one of the benign and common tumors of the limbs and trunk that’s rarely occurs in the abdomin...Read more

• The Study of the Frequency of Antibiotic Usage as an Important Factor in Appearing Antibiotic Resistance in All of the Units in Namazi Hospital

  Microbiology and Infectious Diseases

  As the unusual increase in using antibiotics has been suggested as an indicative factor in appearing antibiotic resistan...Read more

• Inhibition of cell growth in HCT-116 human colorectal cancer cell line by sodium butyrate, a HDAC inhibitor

  Cancer; Prevention, Diagnosis and Treatment

  Sodium butyrate (NaBu), a histone deacetylase (HDAC) inhibitor, is the byproduct of anaerobic microbial fermentation ins...Read more

• Bioinformatics evaluation of hsa-miR-548g related to single nucleotide polymorphism (rs1803622) of GAPDH gene in patients suffering from breast cancer

  Cancer; Prevention, Diagnosis and Treatment

  Breast cancer is one of the most prevailing cancer among females. GAPDH gene is located on chromosome l on position of G...Read more

• The Study of the Requested Antibiotics during Each Patient’s confining to Bed in Namazi 1000 beds hospital, May 22nd to July 21st

  Microbiology and Infectious Diseases

  Occurring resistive microbial trends is one of basic obstacles in infection disease treatments. Prescribing too much ant...Read more

• Application of Nanomaterials in cosmetic industry

  Beauty

  Using nanotechnology in various fields, like electronics, medicine, and now in cosmetics applications has expanded. Glob...Read more

• Gene expression profiling of the 8q22-24 position in human breast cancer: TSPYL5, MTDH, ATAD2 and CCNE2 genes are implicated in oncogenesis, while WISP1 and EXT1 genes may predict a risk of metastasis

  Cancer; Prevention, Diagnosis and Treatment

  Gene expression profiling has been suggested to predict breast cancer outcome. The prognostic value of the 8q22 24 posit...Read more

• Selection of Peptides Specific to PDL-1 Using Phage Display Technology

  Cancer; Prevention, Diagnosis and Treatment

  PDL-1 is a well-known antigen to target tumor specifically. It can interact with PD-1 receptor on tumor infiltrating T-l...Read more

• Biosynthesis of Tellurium nanoparticles by Streptomyces isolate B2.1369F

  Nano-Biotech Medical

  Biosynthesis of Tellurium nano particles (TNPs) has great advantage since it has no chemical contamination in the enviro...Read more

• The latest developments in pharmaceutical biotechnology

  Nano-Biotech Medical

  Background and Aim: Biotechnology has produced over 200 types of drugs and new vaccines that include products for the tr...Read more

• Gene Bookmarking, a way to detect, predict and control molecular processes

  Medical Genetics

  Gene bookmarking is a mechanism of epigenetic memory for gene expression transmission programs, during cell division. ...Read more

• Cancer Stem Cell Therapy Based on Nanostructure Drug Vehicle, PMBN-IL3-GA

  Nano-Biotech Medical

  To overcome difficulty of cancer treatment by conventional chemotherapy methods, the targeting drug delivery based on Na...Read more

• Association of umbilical coiling index with hypothyroidism and gestational diabetes mellitus.

  Metabolism and Metabolic Diseases

  Gestational diabetes mellitus [GDM] and hypothyroidism are prevalent and potentially serious condition which may put mot...Read more

• A novel role for stem cells in anxiety disorders treatment

  Stem cell and Medical Applications

  Anxiety disorders are the most common mental disorders which has affected one-eighth of the world's population. Patients...Read more

• The relationship between serum creatinine and creatinine clearance with the occurrence and severity of coronary artery disease

  Metabolism and Metabolic Diseases

  Cardiovascular diseases are thought to be the most important reason of mortality around the world. Among them coronary a...Read more

• Design And Application Of A Loop-Mediated Isothermal Amplification (LAMP) Assay For Detection Of Tick Borne Relapsing Fever

  Medical Genetics

  Tick borne relapsing fever (TBRF) caused by Borrelia microti is transmitted via bites of the soft tick Ornithodoros erra...Read more

• Molecular Cloning of Clostridium perfringens Type D & Clostridium septicum vaccine strain epsilon alpha fusion gene in E. coli

  Medical Genetics

  Designing and producing a proper fusion construction is the most important problem of producing large quantities of fu...Read more

• The role of Human Papillomavirus Vaccination on cervical cancer: A systematic review

  Cancer; Prevention, Diagnosis and Treatment

  According to International agency for research on cancer (IARC), cervical cancer is the forth reason of death because of...Read more

• New mutation in hotspit region of APC gene in FAP patient in Guilan province

  Medical Genetics

  Familial adenomatous polyposis (FAP) is a colorectal cancer predisposition syndrome characterized by the presence of hun...Read more

• analysis of circulating mir-141, and mir-375 in small cell lung cancer patients

  Medical Genetics

  lung cancer is the main cause of mortality from cancer in the world. small cell lung cancer is the most invasive lung ca...Read more

• Overview the Challenges and Development of regenerative medicine in future

  Stem cell and Medical Applications

  More than 2000clinical trials relating stem cells, there is not a single clinical difficult that is regularly treated wi...Read more

• Blood porphyrin fluorescence peaks and its diagnostic value for early colorectal cancer (CRC) detection

  Cancer; Prevention, Diagnosis and Treatment

  Porphyrins are precursors of Heme metabolism. Any metabolic disorder like cancer can highly affect their level. Since th...Read more

• Synthesis and characterization of Gold Nanoparticles by Isolated Bacterial from Kerman Sarcheshmeh Copper Mine Soil and the study of their cytotoxic properties

  Nano-Biotech Medical

  The present study was designed to isolate bacterial strain capable of gold nanoparticles (Au NPs) production followed by...Read more

• Snake venom: an anticancer agent in immunotoxin therapy

  Cancer; Prevention, Diagnosis and Treatment

  Cancer is the second leading cause of death worldwide. Therefore, many studies are underway to innovate more efficient t...Read more

• Characterization of a carboxypeptidase inhibitor peptide isolated from Iranian scorpion venom glands cDNA library: a good candidate for cancer therapy

  Cancer; Prevention, Diagnosis and Treatment

  Finding a safe strategy for targeting tumor cells without affecting normal cells is one of the goals of cancer treatment...Read more

• The effect of Bioactive glass on Adipose-derived MSC osteogenesis in 3D cultures

  Stem cell and Medical Applications

  Regenerative medicine is an emerging field of biotechnology that combines various aspects of medicine, cell and molecula...Read more

• Recombinant fibroin containing the RGD motif enhances limbal mesenchymal stromal cell adhesion and proliferation

  Stem cell and Medical Applications

  At the periphery of the cornea, in a region called the limbus, exists a population of stromal progenitor cells termed li...Read more

• Molcular Detection of Mupirocin Resistance in Staphylococcus aureus

  Microbiology and Infectious Diseases

  Staphylococcus aureus has become the most common cause of hospital acquired infections over the last few decades. The ba...Read more

• Cytotoxic activity of Berberine on the growth of breast cancer cell line (MCF-7)

  Cancer; Prevention, Diagnosis and Treatment

  Much research has been conducted on the benefits of various phytochemicals in many herbs, fruits and vegetables and thei...Read more

• Investigation of C-582 A>G polymorphism at beta globin cluster gene in beta-thalassemia patients

  Medical Genetics

  Thalassemia is the most prevalent monogenic disorder worldwide resulting from the inappropriate production of heme. pati...Read more

• Evaluation of the HLA-B46 Allelic frequency in the patients with spondyloarthritis syndrome in zanjan province

  Medical Genetics

  Spondyloarthritis is a group of multi-systematic disorders that has been created by spinal features, peripheral jointsan...Read more

• Inflammatory markers, vitamin D status and FokI polymorphism of the VDR gene in overweight women

  Nutrition and Health

  The present study aimed to evaluate the relationship between inflammatory markers, vitamin D status and FokI polymorphis...Read more

• study of microbial quality of some food samples

  Nutrition and Health

  bacterias are considered as the most important factor to cause infection and food poisoning ,so that microbial contamina...Read more

• Triplet repeats in Androgen receptor and it's relation with cardiovascular disease

  Medical Genetics

  Cardiovascular disease is one of the main cause of death in all around the world and researches indicated that in United...Read more

• Survey of beta-lactam hydrolyzing enzymes in Pseudomonas spp. isolated from hospital sewage

  Microbiology and Infectious Diseases

  Background: Beta- lactams are the largest group of antibiotics used by hospitals to treat infections caused by Gram-nega...Read more

• Investigating the Epidemiology of Concussed Patients, Hospitalized in Khatam al-Anbyia and Ali ibn Abi Talib Hospitals in Years 95-96

  Microbiology and Infectious Diseases

  From the point of view of frequency and importance, Brain vascularaccidents take the first place among all the neural di...Read more

• Relationship of pre-body mass index with umbilical coiling index in gestational diabetes and non-gestational diabetes mellitus.

  Metabolism and Metabolic Diseases

  It has been well documented that overweight or obesity before pregnancy is a strong predictor of gestational diabetes me...Read more

• Detection of Mycoplasma arginini contamination in biological products by PCR

  Microbiology and Infectious Diseases

  Introduction: Mycoplasmas are one of the most important pollutants in biological products and cell cultures, and are a...Read more

• Optimization of epi-drug combination against Glioblastoma multiform cell line (U251) using Response Surface Methodology

  Cancer; Prevention, Diagnosis and Treatment

  Glioblastoma multiform (GBM) is the most common and aggressive form of primary brain cancer and has a dismal prognosis, ...Read more

• Identification of bacterial agents of urinary tract infection in patients referred to a laboratory during six months

  Microbiology and Infectious Diseases

  Establishing a diagnosis of symptomatic UTI requires a patient to have symptoms and signs of a UTI and laboratory tests ...Read more

• Simple solution to prevent prostate cancer

  Cancer; Prevention, Diagnosis and Treatment

  Men above fifty five years old are at high risk for malignant prostate cancer. Currently surgery is the only treatment a...Read more

• Using case–control study to find a relationship between SLC11A1 gene and clinical mastitis

  Medical Genetics

  Mastitis is a major source of economic loss in dairy herds. The objective of this research was to evaluate the associati...Read more

• Anticancer Application of Camel Milk: A Review of Recent Research

  Cancer; Prevention, Diagnosis and Treatment

  Because of importance of cancer and the side effects of existing therapies, it is essential to find new therapeutic stra...Read more

• Induction of apoptosis by silibinin in SKBR3 breast cancer cell line through activation of caspase 3/7

  Cancer; Prevention, Diagnosis and Treatment

  The poor prognosis of breast cancer is due to its resistance to the conventional treatments. Therefore, researchers are ...Read more

• An Evaluation of Tissue Destruction Time in Phrenic Nerve after Death and Counting the Number of Nerve Fibers in C3, C4 and C5 Branches

  Cancer; Prevention, Diagnosis and Treatment

  مقدمه اعصاب فرنیک چپ و راست، محرک اصلی عضلة دیافراگم میباشند( .)5ای...Read more

• studying the effect of silibinin in some of hippo signaling pathway genes , in T47D and MCF7 Breast cancer cell lines with 3D culture.

  Cancer; Prevention, Diagnosis and Treatment

  Breast cancer is one of the most common malignancy diseases world and is the second leading cause of cancer in women. S...Read more

• Stress-induced immobility in male and female rats and its effects on offspring numbers, sex ratios and sexual hormones

  Women and Reproductive Health

  Stress-induced immobility inhibition of reproductive functions and can effect on sexual hormones. Increasing/decreasing ...Read more

• Structural Study of Lysozyme upon Interaction with Plasmonic gold Nanoparticles

  Nano-Biotech Medical

  Recent advances in nanotechnology have encouraged scientists to design hybrid systems of nanoparticles and biological ma...Read more

• Examination of mutations in QRDRs in ParC, ParE genes Salmonella Clinical Examples of Zahedan Hospitals

  Microbiology and Infectious Diseases

  Salmonellosis is a major public health problem worldwide. Although most Salmonella infections result in mild self-limiti...Read more

• Berberine induced cell death of human colon cancer HT-29 through mediating of PARP

  Cancer; Prevention, Diagnosis and Treatment

  Berberine is an isoquinoline which has many various pharmacological activities, including anticancer activities. Poly (A...Read more

• Finding a new approach for Treatment of osteoporosis with trace element and antioxidant in rat animal model

  Metabolism and Metabolic Diseases

  One of the most common bone metabolic and endocrinal disorders is osteoporosis. It is defined by progressive bone loss, ...Read more

• Omega-3 and its effects on colorectal cancer

  Cancer; Prevention, Diagnosis and Treatment

  Cancer as the second leading cause of death has always been a threat to human life and due to its peculiar nature and la...Read more

• Determination of GPR55 overexpression by quantitative real-time PCR as a biomarker for skin SCC detection

  Cancer; Prevention, Diagnosis and Treatment

  Chronic wounds resemble the wounds arising with skin squamous cell carcinoma (SCC). Since they are cancerous, they shoul...Read more

• Relationship between a phenotype and one gene

  Medical Genetics

  Study of whole genomes is genomic. The genes contain instructions for protein synthesis that are the functional part of ...Read more

• Association between Biochemical Markers BHCG in Screening First Trimester of Pregnancy in Women with PCOS

  Women and Reproductive Health

  PCOS (polycystic ovary syndrome) is a common endocrine system disease among women of reproductive age. Its prevalence in...Read more

• FGF10: Type III Epithelial Mesenchymal Transition and Invasion in Breast Cancer Cell Lines

  Cancer; Prevention, Diagnosis and Treatment

  Metastasis is one of the important characteristics of a cancer cell. the process called epithelial mesenchymal transitio...Read more

• Evaluation of Salmonella.spp in Synovial Fluids of Arthritis Patients by Molecular Method

  Microbiology and Infectious Diseases

  Arthritis is an inflammation of the joints. This complication is often accompanied by pain, swelling, stiffness and heat...Read more

• Synergistic effect of berberine and theophylline on apoptosis induction in MDA-MB-231 cells

  Cancer; Prevention, Diagnosis and Treatment

  Breast cancer is the most common type of cancer and a leading cause of cancer mortality among women. Berberine is an iso...Read more

• Genetic Diversity and Phylogenetic Analysis of the Iranian Leishmania Parasites Based on HSP70 Gene PCR-RFLP and Sequence Analysis

  Microbiology and Infectious Diseases

  Despite the broad distribution of leishmaniasis among Iranians and animals across the country, little is known about the...Read more

• Ginseng For Improving The Quality Of Life In People With Cancer and Fatigue- A Systematic Review

  Cancer; Prevention, Diagnosis and Treatment

  Background and purpose: An important issue in cancer health care is the improvement in quality of life (QoL). Physicians...Read more

• Association study of rs369770942 of neuregulin1 gene 3'UTR with schizophrenia

  Medical Genetics

  : Schizophrenia is a mental disorder and affects approximately 1% of global population. This study suggests that rs36977...Read more

• Lantibiotics: New generation of antimicrobial drugs

  Microbiology and Infectious Diseases

  These days, due to antibiotic resistance in bacteria, scientists are eager to find new generation ‎drugs. Lantibiotics...Read more

• Evaluation and study of antimicrobial activity of nanoliposomal meropenem against Pseudomonas aeruginosa isolates

  Nano-Biotech Medical

  The aim of this study was to evaluate the antimicrobial efficacy of liposomal meropenem formulation against clinical and...Read more

• Protective effect of silymarin on plasma membrane and DNA integrity of human sperm treated with cadmium chloride

  Women and Reproductive Health

  Cadmium, as an environmental pollutant, exerts its destructive effects on male reproductive system and sperm by inducing...Read more

• A Review of the Fungi Generating the Cellobiose Dehydrogenase Enzyme to Remove Bacterial Biofilms

  Microbiology and Infectious Diseases

  The biofilm causes more than 60% of nosocomial infections and 65% human infections. Bacteria in biofilms society are res...Read more

• Drafting maggot therapy in personalized cancer therapy

  Cancer; Prevention, Diagnosis and Treatment

  In some personalized cancer therapies the elimination of the tumor will be a result of the injection of flesh- eating ba...Read more

• The effects of methanolic soy extract on ovary tissue modification in model of polycystic ovary syndrome as an inflammation state

  Women and Reproductive Health

  Introduction and Objective: Chronic low-grade subclinical inflammation has been increasingly recognized as an interposer...Read more

• Relationship between Hypertension in the First Trimester of Pregnancy with Weight and Height at Birth

  Women and Reproductive Health

  Background: Hypertensive disorders with a prevalence of %5-10 are among the main causes of morbidity and mortality in mo...Read more

• Dendrosomal curcumin nanoformulation modulate apoptosis-related genes and protein expression in hepatocarcinoma cell lines.

  Nano-Biotech Medical

  Introduction: The side-effects observed in conventional therapies have made them unpromising in curing Hepatocellular c...Read more

• Whole-Exome Sequencing Identifies R1279X of MYH6 to be Associated with Congenital Heart Disease and Other Malformations

  Medical Genetics

  Myosin VI, encoded by MYH6, is expressed dominantly in human cardiac atria and plays consequential roles in cardiac musc...Read more

• Association of rs699 Polymorphism in AGT Gene with Coronary Heart Disease Risk

  Medical Genetics

  The rs699 transition in human angiotensinogen (AGT) gene, result in methionine (M) to threonine (T) substitution at codo...Read more

• The influence of lactobacillus fermentum cytoplasmic extract, isolated from traditional cheese (kuzeh) on the expression of p53 gen in K562 cancerous array via a quantitative Real time PCR method

  Cancer; Prevention, Diagnosis and Treatment

  the probiotics are able to induce apoptosis in cancerous cells. chronic myelocytic leukemia (cancerous array of K562) is...Read more

• The comparative proteomic pattern study of albumin fraction in type I Gaucher Patients with 2 Dimensional Electrophoresis

  Metabolism and Metabolic Diseases

  The gaucher disease is the most common type of lysosomal storage diseases that, particularly affects the macrophage cell...Read more

• Comparison of Antibacterial Activity of Essential Oil of Varieties of Calendula Plant from Varamin (Iran) on Escherichia coli and Staphylococcus aureus

  Microbiology and Infectious Diseases

  Uncontrolled use of conventional antibiotics and synthetic antibacterial medicine has led to the proliferation of microb...Read more

• Association of selenoprotein S expression and its variants with metabolic syndrome in subjects with cardiovascular disease

  Metabolism and Metabolic Diseases

  Selenoproteins S (SELS or VIMP) may regulate cytokine production, and thus play a key role in the control of the inflamm...Read more

• Cloning and expressing the chimeric peptide lactoferricin-lactoferampin camel in Lactococcus lactis for promising as a candidate for oral medication

  Nutrition and Health

  Lactococcus lactis is known as probiotics due to its lack of harmful toxins. Because of its high growth potential and re...Read more

• Anti-cancer effect of redroot pigweed as weed plant species

  Cancer; Prevention, Diagnosis and Treatment

  Leukemia cancer is currently one of the major causes of cancer-related deaths among humans. Extracts of plants including...Read more

• Study of HER2 gene expression in AGS cell line after treatment of cells with Crocus sativus (Iranian Saffron) extract

  Cancer; Prevention, Diagnosis and Treatment

  The study of HER-2 gene in cancers, especially gastric cancer, is of great importance. This gene, has been shown to inc...Read more

• Knowledge and Practice of Breast Self-Examination Among Female Students in Sari Islamic Azad University in 2015-2016

  Cancer; Prevention, Diagnosis and Treatment

  Breast self-examination (BSE) is one of the ways of prevention and early detection of breast cancer. The aim of this stu...Read more

• Determination of physico-chemical properties of Faecalibacterium prausnitzii EVs

  Microbiology and Infectious Diseases

  Faecalibacterium prausnitzii is one of the most common human gastrointestinal bacteria that has been shown to have sever...Read more

• Designing and cloning and expression of bean defensin in human embryonic kidney cells and evaluating their antibacterial function

  Microbiology and Infectious Diseases

  Defensins are among the most important cationic peptides that their presence in a wide range of herbs and animals has be...Read more

• Effect of genistein associated with agonist (17-β estradiol) on the viability and apoptosis of human hepatocellular carcinoma HepG2 cell line

  Cancer; Prevention, Diagnosis and Treatment

  Background: One of the most lethal cancers is Hepatocellular carcinoma (HCC). Genistein (GE) is a choice compound for tr...Read more

• Development of an Antagonistic TGF-β by Directed Blocking of its TβRI Binding Site to Inhibition TGF-β Signaling

  Cancer; Prevention, Diagnosis and Treatment

  Transforming growth factors beta (TGF-βs) play vital roles in regulating cell growth, differentiation and inflammation....Read more

• Interference of Dopamine D2 Receptors and Food Restriction on Changing Anxiety Behavior and Serum Biochemical Factors in Adult Male Rats

  Nutrition and Health

  Background: Food restriction (FR) and dopaminergic system affect on anxiety behavior, but it has not been determined the...Read more

• Evaluation of cytotoxicity of aqueous-ethanolic extract of pineapple on ovarian cancer cells (A2780 cell line)

  Cancer; Prevention, Diagnosis and Treatment

  Today, the global trend towards the use of herbal medicines for treating diseases has tended, while developed countries ...Read more

• Recent study about Genetics of Human Obesity

  Medical Genetics

  Obesity has become a global epidemic and contributes to the increasing burden of type 2 diabetes, cardiovascular disease...Read more

• Fast detection of Pseudomonas aeruginosa keratitis by Polymerase Chain Reaction (PCR)

  Microbiology and Infectious Diseases

  Pseudomonas aeruginosa is an opportunistic pathogen that has different virulence factors. This organism is commonly foun...Read more

• Optimization of the best concentration of Aloe vera extract for treating gastric cancer cells in order to reduce HER-2 gene expression

  Cancer; Prevention, Diagnosis and Treatment

  HER2 is a glycoprotein that has tyrosine kinase activity and plays an important role in guiding growth signals. Its expr...Read more

• In silico analysis of Siglec14 as a target for hsa-let-7e-5p

  Medical Genetics

  Sialic acid-binding immunoglobulin-type lectins (Siglecs) are transmembrane proteins that are expressed on the cell surf...Read more

• Study of DNA methylation pattern in sf-1 gene promoter region in endometriosis tissue samples of women in north west of Iran

  Medical Genetics

  Endometriosis is an estrogen-dependent inflammatory disease. Its defining feature is the presence of endometrium-like ti...Read more

• Structural Study of Horseradish Peroxidase upon Interaction with Gold Nanoparticles

  Nano-Biotech Medical

  Remarkable advancements have been made in the field of nanotechnology, including design of hybrid systems of nanoparticl...Read more

• A genetic variant in Multiple drug resistance gene is associated with poor prognosis of patients with esophageal squamous cell carcinoma

  Cancer; Prevention, Diagnosis and Treatment

  Esophageal squamous cell carcinoma (ESCC) is one of the causes of death from cancer. Several genetic variants in the 7q2...Read more

• Investigation of mutations and polymorphisms in exon 11, 12, 22 and 23 in Non Caucasian cystic fibrosis patients from the north of Iran

  Medical Genetics

  Cystic fibrosis (CF) is the most common autosomal recessive disease in Caucasians, caused by mutation in cystic fibrosi...Read more

• The study of Apolipoprotein E4 allele distribution in parents of Down's syndrome children as a risk factor in Iran

  Medical Genetics

  Down syndrome(DS) is the most common chromosomal abnormality.The most important factor in DS is increased maternal age s...Read more

• HETEROGENEITY OF ESCHERICHIA COLI ISOLATES WITHIN DIFFERENT

  Microbiology and Infectious Diseases

  Aim:Escherichia coli is one of the most important bacterial pathogens causing urinary tract infections (UTIs) . This bac...Read more

• Impact of GSTP1 genetic polymorphisms on susceptibility risk of chronic myeloid leukemia

  Cancer; Prevention, Diagnosis and Treatment

  Genetic variation influencing individual susceptibility to chemical carcinogens is one of the main factors leading to ca...Read more

• NRG1 expression changes in Autism spectrum disorder and play role in executive functions abnormalities

  Medical Genetics

  Autism spectrum disorder (ASD) is a pediatric heterogeneous psychiatric and neurodevelopment disorder with social and co...Read more

• Tamoxifen-induced rapid death of GPER positive cell lines by modulating RAS/MAPK signaling pathway

  Cancer; Prevention, Diagnosis and Treatment

  Breast cancer is the most common cancer in women worldwide. Tamoxifen is a nonsteroidal selective estrogen receptor modu...Read more

• Streptococcus mutans detection in Dental Plaque and saliva Samples

  Microbiology and Infectious Diseases

  Dental caries is one of the most common prevailing disease in humans and a significant public health problem worldwide. ...Read more

• Atopic Dermatitis and treatment

  Nutrition and Health

  • diagnostic criteria Atopic dermatitis is difficult to define because of its variable morphology and distribution an...Read more

• Isolation and identification of probiotic bacteria from human milk

  Microbiology and Infectious Diseases

  Background: Breast milk is the best nutritional supplement during the first few months of the baby's life. It contains v...Read more

• The Bioinformatic prediction of selected miRNAs role in regulation of cell death pathways in Parkinson’s disease

  Medical Genetics

  Parkinson's disease (PD) is the second most common neurodegenerative disease. Due to its unknown etiology and pathology,...Read more

• Effects of administration of trimethoprim/sulfamethoxazole and folic acid on ovarian histopathology in adult female rats

  Women and Reproductive Health

  Previous studies have reported the antifertility activities of sulfonamides. This study was designed to evaluate the eff...Read more

• A Turn-Off Fluorescent Sensor Based On Carbon Dots for Sensitive Detection of Tetracycline in Milk

  Nutrition and Health

  The detection of tetracycline in animal-derived food and drug is very significant, because of its harmful effects on hum...Read more

• Determining the Interactions between Major Dietary Patterns and LRP5 Genotypes (rs556442) on Bone Discordance in Postmenopausal Women Referred to Shariati Hospital

  Nutrition and Health

  One of the challenges in the diagnosis of osteoporosis is bone discordance. Many studies have confirmed an association ...Read more

• An innovative field of plasma application for medical therapy

  Microbiology and Infectious Diseases

  Plasma medicine is an innovative and emerging field combining plasma physics, life science and clinical medicine. Recent...Read more

• Evaluation of circulating prognostic tumor marker DNA in the blood of brain tumor patients

  Cancer; Prevention, Diagnosis and Treatment

  Recent evidence suggests that tumor cells may release DNA into the circulation, which is enriched in the serum and plasm...Read more

• Anti-Diabetic Effects of Methanolic Extract of Calendula officinalis through Increased Antioxidant Enzymes Activity

  Metabolism and Metabolic Diseases

  Diabetes is a big challenge in the health care system. ROS generation is the major mechanisms which is involved in the p...Read more

• Effect of different Electromagnetic fields (EMF) on sperm viability and motility

  Women and Reproductive Health

  Today, due to the advancement of the level of technology, electromagnetic fields (EMS) from various industries affect...Read more

• TThe Biological Effects of Aqueous Extract of Ephedra major on the Development of Balb/C Mouse Embryos 7Th to 10Th Days of Pregnancy

  Nutrition and Health

  Aqueous extract of Ephedra major used as a drug for blood pleasure, sleep disorder and lose weight. But it is effects on...Read more

• Molecular screening for E255K mutations in Imatinib Resistant-CML

  Medical Genetics

  Chronic myelogenous leukemia (CML) is a clonal disease that kind of hematopoietic stem-cell cancer. A significant number...Read more

• Tuberculosis is a common HIV infection, control and treatment

  Microbiology and Infectious Diseases

  Points out Pulmonary that more than all the be without lymph node, pylorus , Urinary tract , bones and joints , meninge...Read more

• Biosynthesis of Gold nanoparticles by Areca palm fruit extract

  Nano-Biotech Medical

  Targeted drug delivery by Gold nano particles (AuNPs) is a new era in pharmaceutical research; i.e. curing tumoral cance...Read more

• Study of PAX5 gene expression in patients with gastric cancer

  Cancer; Prevention, Diagnosis and Treatment

  Gastric cancer is one of the biggest health problems in the world. Due to the lack of many carcinogenic biomarkers and t...Read more

• Genes involved into both alternative splicing and aging pathways as biomarkers for Parkinson Disease diagnosis

  Medical Genetics

  Parkinson's Disease is a degenerative movement disorder that exhibit symptoms through progressive loss of dopaminergic...Read more

• Experimental and theoretical investigation on Mandelic acid (R, S) enantioselective separation using Vancomycin chiral column in high performance liquid chromatography

  Nano-Biotech Medical

  Nowadays, antibiotic chiral columns can be used in various chromatography separations. The high potential of these compo...Read more

• A genetic variant in CDKN2A/2B locus was associated with poor prognosis in patients with esophageal squamous cell carcinoma

  Cancer; Prevention, Diagnosis and Treatment

  Esophageal squamous cell carcinoma (ESCC) is among the leading causes of cancer related death. Despite extensive efforts...Read more

• Evaluation of the effects of fish oil-derived Eicosapentaenoic acid on the proliferation of colorectal cancer cell line (hct116)

  Cancer; Prevention, Diagnosis and Treatment

  of these studies have indicated that Eicosapentaenoic acid (EPA) can induce apoptosis and reduce proliferation in cancer...Read more

• Evaluation of Adenovirus in Pseudomonas aeruginosa susceptible keratitis by PCR molecular method

  Microbiology and Infectious Diseases

  Keratitis is inflammation of the cornea of the eye. In keratitis, microbial agents are important. In the presence of inf...Read more

• Nanodispersion-loaded mucoadhesive polymeric inserts for ocular drug delivery: scale up production

  Nano-Biotech Medical

  Frequent use of highly concentrated solutions may induce toxic side effects and cellular damage at the ocular surface. T...Read more

• Therapeutic effects ellagitannin on non communicable diseases

  Nutrition and Health

  Today, due to the complications caused by the treatment with chemical drugs, the scientists focus on to use of complemen...Read more

• Purification of poly ribosylribotil phosphate capsule from Heamophilus influenza type- b strain ATF2 cultivated in bioreactor

  Microbiology and Infectious Diseases

  Haemophilus influenzae is a small gram negative cocobacilli non motile and can be seen as pleomorphic. H.inf.can cause ...Read more

• Easy and efficient purification of flagellin from salmonella typhimurium ATCC 14028 without necessity of ultracentrifugation

  Microbiology and Infectious Diseases

  Gram negative bacteria's Flagellin has many applications in diagnosis, treatment and vaccines. fliC, the major protein o...Read more

• Influence of CYP2D6 and CYP3A4 genetic polymorphisms on susceptibility risk of chronic myeloid leukemia and treatment response

  Cancer; Prevention, Diagnosis and Treatment

  Xenobiotic- metabolizing enzymes compose an important line of defence against a variety of carcinogenes and environmenta...Read more

• Cell-Penetrating Peptides and Tumor Targeting Peptides: achievements and challenges in application for cancer treatment

  Cancer; Prevention, Diagnosis and Treatment

  Despite significant advancement in the anti-cancer drugs recently, cancer still remains one of the leading causes of dea...Read more

• Intelligent Stimuli Responsive Core@Sell Nanobiomaterial: Biomedical Opportunities and Challenges

  Nano-Biotech Medical

  Nanoscale objects are powerful devices in biotechnology medicine and biomedical sciences. They are potential applicants ...Read more

• A brief review of regenerative dentistry

  Stem cell and Medical Applications

  Tissue regeneration idea has been formed by stem cells identifying and tissue engineering techniques. Stem cells can be ...Read more

• Dexamethasone induced growth inhibition in HT-29 human colorectal cancer cells

  Cancer; Prevention, Diagnosis and Treatment

  Dexamethasone is a type of corticosteroid medication. Dexamethasone has anti-inflammatory effects that are produced via ...Read more

• Evaluation of nitrosative stress in sprayer workers

  Metabolism and Metabolic Diseases

  Agricultural pesticides have an important impact on human health and farmers are people who are more exposed to pesticid...Read more

• The impact of miR-16 and miR-34a overexpression on the migratory and invasive potential of breast cancer cells

  Cancer; Prevention, Diagnosis and Treatment

  Breast cancer (BC) is the most frequent type of cancer and a main cause of cancer-related deaths among women worldwide. ...Read more

• Investigating the effects of saffron and melatonin with radiotherapy on viability of Hela cells

  Cancer; Prevention, Diagnosis and Treatment

  Nowadays, a lot of people in the worldwide dead because of cancer. Despite much research in this area, there is still no...Read more

• Investigating the presence of chemical compounds in pineapple

  Cancer; Prevention, Diagnosis and Treatment

  Pineapple is a member of the Ananasian family, it is a sub-tropical fruit. It has many chemical compounds that are impor...Read more

• Interaction of rs783540 of CPEB1 gene in patients with azoospermia

  Medical Genetics

  : Publicly, 90% of fertile couples get pregnant in one year. Therefore, infertility refers to disability in pregnancy, a...Read more

• The effect of 5μM benzoquinone JAG1 and Wnt5a genes in mesenchymal stem cells(MSCs) found in bone marrow(BM) niche

  Stem cell and Medical Applications

  Benzoquinone(BQ) is one of benzene metabolite after entering body, its prolonged presence in body leads to blood disorde...Read more

• Evaluation of TCA cycle in patients with acute myeloid leukemia

  Cancer; Prevention, Diagnosis and Treatment

  Acute myeloid leukemia (AML) is the most type of acute leukemia in adults. In solid tumors, alteration of energy metabol...Read more

• Expression of CD74 in Ovarian cancer

  Medical Genetics

  Ovarian cancer is a cancer that forms in or on an ovary. The pro-inflammatory cytokine migration inhibitory factor (MIF)...Read more

• the effect of crocin on forgetfulness caused by cholestasis in male rats(behavioral , biochemical and genetical )

  Metabolism and Metabolic Diseases

  cholestasis is a condition in which the bile ducts that carry bile from the liver to the intestine to dispose, is blocke...Read more

• study of mesenchymal stem cell differentiation to chondrocyte on electrospun nanofibrous polyvinyl alcohol alginate sulfat blend

  Stem cell and Medical Applications

  Cartilage tissue engineering is used as a potential solution for replacing or repairing damaged tissue. In this method, ...Read more

• The effects of preconditioning mesanchymal stem cells with hydrogen peroxide and serum deprivation on cell viability and apoptosis.

  Stem cell and Medical Applications

  It is known that application of mesenchymal stem cells is an effective treatment in many diseases. Despite of cell thera...Read more

• Chrysin therapy could suppress breast cancer development

  Cancer; Prevention, Diagnosis and Treatment

  Chrysin is a natural flavonoid found abundantly in honey, gum, and many plant extracts. It rep¬resents anti-cancer feat...Read more

• The effect of berberin on histone H1 in lung cancer A549

  Cancer; Prevention, Diagnosis and Treatment

  Berberin, a naturally occurring isoquinoline alkaloid, is present in a number of important medicinal plants. Berberin ha...Read more

• Genetic variations of Cholesteryl ester transfer protein and diet interactions in relation to lipid profiles and coronary heart disease: A systematic review

  Nutrition and Health

  The number of investigations on diet–genotype interactions in the prevention or treatment of dyslipidemia have increas...Read more

• Microfluidic Nanocomplex-Based Localized Gene Delivery Platform for Bone Tissue Engineering.

  Stem cell and Medical Applications

  Annually more than 2.2million bone graft procedures take place in worldwide. Biomaterials-based bone tissue engineering ...Read more

• Pregnancy management in Iranian Traditional Medicine

  Women and Reproductive Health

  Managing complications in pregnancy is so important cause of sensitive situation of the mother and the fetus. Physicians...Read more

• Poly(A)-tail shortening Length: an Alternative Epigenetic Mechanism for Translational Control of Oncogenes

  Medical Genetics

  : mRNA poly(A) tails in 3'UTR is important for its stability and translation. t is observed Poly(A) tails is dynamic and...Read more

• The effect of manual acupuncture on anthropometric parameters in obese and overweight patients

  Nutrition and Health

  Obesity is a chronic disease which is on the increase. Treatments of obesity include diet therapy, exercise, behavior th...Read more

• The role of artificial intelligence in medical decisions

  Nano-Biotech Medical

  The term "artificial intelligence" was used in 1956. There is still no definitive definition of artificial intelligence ...Read more

• Investigation of A New Paclitaxel Nano Niosomal formulation and Biological Evaluation of Entrapped Paclitaxel on breast cancer cell line

  Nano-Biotech Medical

  Regarding that the breast adenocarcinoma is the most widespread disease among women, paclitaxel, an anti-cancer drug, co...Read more

• Polymorphisms evaluation of the thiopurine S-methyltransferase gene among the Iranian acute lymphoblastic leukemia population

  Medical Genetics

  Thiopurine S-methyltransferase (TPMT) is a cytosolic enzyme which catalyzing the S-methylation of 6-mercaptopurine and...Read more

• The effects of specific expression of Apoptin under control of PSES and PSA promoter on apoptosis of LNCaP cells

  Cancer; Prevention, Diagnosis and Treatment

  Apoptotic effects of viral protein Apoptin has been demonstrated in numerous studies. However, its tumor specificity has...Read more

• Diet and lifestyle habit imoact on bone density in postmenopausal women

  Nutrition and Health

  Menopause is the stage of a woman's life, typically between the ages of 45 and 55, when she stops having menstrual perio...Read more

• Evaluation and comparison of digestion in two traditional and contemporary medicine schools And its effect on the treatment of diseases

  Nutrition and Health

  Proper nutrition is one of the principles of "preserving health" in traditional and contemporary medicine. Wha...Read more

• Investigation Of Antimicrobial Effect Of Magnetical Silver And Silver-Titanium Dioxide Nanocomposites On Commonly Bacteria Of Urinary Infects

  Nano-Biotech Medical

  Recently, developed nano composite with highly efficient antimicrobial properties are considered. In this study, A new m...Read more

• rDKK1 production and purification as an antigen

  Cancer; Prevention, Diagnosis and Treatment

  A critical goal in prevention and control of cancer is early detection of cancer. It is suggested that the Dickkopf1 (DK...Read more

• The effect of Chlorogenic acid on Insulin, GIP and GLP-1 level in healthy humans: A systematic review

  Nutrition and Health

  According to previous studies, there are different supplements in order to prevent and treat diabetes. These studies sho...Read more

• Antimicrobial effects of new designed 2-amino-tetrahydro-4H-chromene-3-carbonithril derivatives against some pathogenic microbial strains

  Microbiology and Infectious Diseases

  Chromenes are natural compounds which also called benzopyrane derivatives and chromene-4-one and had several biological ...Read more

• Chimeric Antigen Receptors (CARs) as a powerful approach for cancer therapeutics

  Cancer; Prevention, Diagnosis and Treatment

  T-cells have the potential to extirpate abnormal cells. The genetic modification and characterization of T-cells with ch...Read more

• The efficacy of Leptin on physical and psychological stress causing gastric ulcer: Participations of nitric oxide and prostaglandin E2

  Nutrition and Health

  The present study aimed to assess the effects of Leptin on physical and psychological stresses inducing gastric ulcer. T...Read more

• Crocin suppresses multidrug resistance in MRP overexpressing ovarian cancer cell line

  Cancer; Prevention, Diagnosis and Treatment

  Crocin, one of the main constituents of saffron extract, has numerous biological effects such as anti-cancer effects. M...Read more

• The Evaluation of Methicillin Resistant Staphylococcus aureus (MRSA) Colonization on Skin Lesions in Patients with Psoriasis

  Microbiology and Infectious Diseases

  Psoriasis is a chronic and inflammatory disease of the skin. Recently, the role of microbial agents in the development o...Read more

• Optical, structural and antibacterial properties assessment of ZnO:Mn nanoparticles

  Nano-Biotech Medical

  with the rapid development of human life, controlling the harmful impacts of microorganisms is essential. The current st...Read more

• Evaluating the genetic variations in functional domains coding regions of MSMB in infertile men with unexplained infertility

  Medical Genetics

  Β-Microseminoprotein(MSMB) is one of the most abundant proteins in human seminal plasma. This protein binds to head and...Read more

• Investigating the incidence of cardiovascular in patients with ercutaneous coronary interventionin Bandar Abbas Shahid Mohammadi Hospital

  Metabolism and Metabolic Diseases

  PCI(Percutaneous coronary intervention) is one of the most common mode of re vascularization. so According to the impo...Read more

• Interaction of an anti-cancer drug Crizotinib with serum albumin: A docking study

  Cancer; Prevention, Diagnosis and Treatment

  Cancer treatment is one of the major challenges of medical science today. Among them, lung cancer is a common type of ca...Read more

• The Relationship Between Renin- Angiotensin System Genetic Variation and Autism in Iranian Children; A Case –Control Study

  Medical Genetics

  Autism is a disease of complex nature with a significant genetic component.The importance of Renin-Angiotensin System(RA...Read more

• Toxoplasmosis infection in the pregnant women in the first trimester in yasouj city

  Women and Reproductive Health

  Toxoplasmosis is a shared human-animal disease with worldwide distribution caused by Toxoplasma gondii. More than half o...Read more

• Constructing a Novel Hypoxia-Inducible Bidirectional shRNA Expression Vector for Simultaneous Genes Silencing in Colorectal Cancer Gene Therapy

  Cancer; Prevention, Diagnosis and Treatment

  Background: RNA interference (RNAi) is an efficient genetic approach in gene-specific knockdown and gene therapy; howeve...Read more

• The nutritional benefits of Pistacia atlantica

  Nutrition and Health

  Pistacia Atlantica Mutica is a genus of the family Anacardiaceae which consist of different parts such as fruit, leave a...Read more

• Targeted killer gene therapy of breast cancer cells using Pseudomonas exotoxin A

  Cancer; Prevention, Diagnosis and Treatment

  Targeted expression of killer genes in tumor cells ensures specific elimination of cancer cells with minimal effect on n...Read more

• Cytotoxicity study of nanoparticles containing aminoglycosides

  Nano-Biotech Medical

  Aminoglycosides are a bunch of antibiotics that inhibit the synthesis of protein in bacteria and lead to eradication of ...Read more

• Site Directed Mutagenesise of L-Asparagine as an Improveed Anti Cancer Protein with Increased L-ASNase Activity

  Cancer; Prevention, Diagnosis and Treatment

  L-Asparaginase (L-ASNase) is an FDA approved enzyme which is widely used in fight against acute lymphoblastic leukemia a...Read more

• Biological and Molecular Diversity in Telomerase: Characteristics of hTERT in Human, Vertebrates and Yeast

  Medical Genetics

  hTERT (human telomerase reverse transcriptase) is the catalytic subunit of telomerase enzyme, and is essential for its ...Read more

• Insulin resistance in addicted people: experimental study along with in vitro study and data mining Techniques

  Metabolism and Metabolic Diseases

  This study was planned to survey the inflammatory and antioxidant and other Insulin Resistance related condition in addi...Read more

• The effect of Rosa canina extract on Bax gene expression in gastric adenocarcinoma cell line(AGS)

  Cancer; Prevention, Diagnosis and Treatment

  Gastric cancer is the most common cancer in the world. It occurs as a result of many factor and there is massive invest...Read more

• Evaluation of the interaction between hemoglobin protein and angiotensin-inhibitory peptide by three-dimensional fluorescence method in the absence and presence of low-frequency electromagnetic fields

  Metabolism and Metabolic Diseases

  Million people in worldwide are suffering from high blood pressure and related diseases. Over the past two decades, ther...Read more

• Involvement of Mu Opioid Receptor Signaling in the Protective Effect of Opioid against 6-Hydroxydopamine-Induced SH-SY5Y Human Neuroblastoma Cells Apoptosis

  Cancer; Prevention, Diagnosis and Treatment

  1. Introduction arkinson’s disease (PD) is a neurodegenerative disease caused by losing dopaminergic neurons of the ...Read more

• Study of properties of Juglans regia plant on women’s health

  Women and Reproductive Health

  Juglans regia plant is one of Iranian native plants that some of it’s productive types are in Markazi province. The b...Read more

• Effect of Hypiran on the oxidative stress responses in experimental autoimmune encephalomyelitis

  Nutrition and Health

  Experimental autoimmune encephalomyelitis (EAE) is an animal model of multiple sclerosis. The hallmark of this disease i...Read more

• Development of a chemiluminometric lateral flow biosensor for sensitive detection of Escherichia coli

  Microbiology and Infectious Diseases

  Paper based nucleic acid testing (NAT) has attracted significant interest in point of care diagnostic field. Lateral flo...Read more

• Investigation of cytotoxicity, cell cycle and induction of apoptosis by methyl-thiosemicarbazone complex with Cu2+ in K562 cell line

  Cancer; Prevention, Diagnosis and Treatment

  Thiosemicarbazone compounds have previously been considered as a new series of potent apoptosis-inducing agents. In the ...Read more

• Microencapsulation and double-coating of probiotic bacteria for enhancement of their viability and targeted delivery

  Nutrition and Health

  The purpose of this study was to assess the protecting character of double coated beads of alginate-chitosan-Eudragit S1...Read more

• Food Patterns and Framingham Risk Score in Iranian Adults: Tehran Lipid and Glucose Study: 2005-2011

  Nutrition and Health

  Healthy dietary habits can prevent cardiovascular diseases (CVD). The aim of the present study was to investigate the as...Read more

• Design and expression of an immunogenic construct based on calcium sensing receptor antigen

  Cancer; Prevention, Diagnosis and Treatment

  Due to texture and small size, identifying the parathyroid from thyroid glands is a very difficult procedure. They shoul...Read more

• Design and evaluation of a selective delivery system to induce antimiR-155 function

  Nano-Biotech Medical

  Developing RNA/DNA aptamer-miRNA chimera represents an effective approach in targeted gene therapy of cancer. In additio...Read more

• The Role of Nanobiotechnology in Identification and Treatment Lung Cancer

  Nano-Biotech Medical

  Nanotechnology is the engineering of functional systems at the molecular scale. Therefore, it is possible to combine nan...Read more

• Comparative investingation of effects of the agricultural pesticides (diazinon and chlorpyrifos) on spermatogenesis in male BALB/c male mice

  Nutrition and Health

  Diazinon and chlorpyrifos are kind of organophosphate toxins used for agricultural pests. These toxins control acetylch...Read more

• EFFECT OF CHRYSIN NANO-PARTICLES TREATMENT ON ESTROGEN RECEPTORS EXPRESSION LEVELS IN BREAST CANCER CELL LINE

  Nano-Biotech Medical

  Breast cancer (BC) is increasing in the developing countries. Estrogens are supposed to play roles in BC initiation and ...Read more

• A foundation for universal T-cell based adoptive immunotherapy

  Cancer; Prevention, Diagnosis and Treatment

  The patient-specific autologous therapy could be a significant limiting factor in the large-scale exploitation of CAR te...Read more

• Association of Cytochrome P450 2C19 (CYP2C19) gene polymorphism and the risk of endometriosis in Iranian population

  Women and Reproductive Health

  Endometriosis is a chronic disease that is characterized by the occurrence of endometrial glands and stroma outside the ...Read more

• Frequency of TEM and SHV genes in the strains of Acinetobacter producing broad-spectrum isolated ß-lactamases from Zahedan patients by PCR method

  Microbiology and Infectious Diseases

  Acinetobacter baumannii is one of the most important factors in hospital infections, and its Colonization rate in hospit...Read more

• Antibody-drug conjugates; a Novel class of cancer treatment

  Cancer; Prevention, Diagnosis and Treatment

  One of the most effective therapeutic agents used in targeted cancer therapies is antibody. Due to lack of permeability ...Read more

• Study of Effects of Crushed PLGA Nano-fiber Percentage on The Cell Proliferation in Chitosan-Gelatin-βGlycerophosphate Cartilage Scaffold

  Nano-Biotech Medical

  Articular cartilage has poor reparative capabilities. So Osteoarthritis is widespread globally in almost 70% of people o...Read more

• The Role of Viral Proteins VP24 and VP35 in The Pathogenesis of The Ebola Virus

  Microbiology and Infectious Diseases

  The Ebola virus is a member of the Filoviridae family, which is causing hemorrhagic and fatal fever to humans. Ebola is ...Read more

• Effect of intracerebroventricular injection of Adenosine on food and fat intake in neonatal chicks

  Nutrition and Health

  The present article was aimed to clarify the role of central Adenosine on food intake in neonatal chicks. Adenosine is n...Read more

• Qualitative and quantitative evaluation of airborne microorganisms and the concentrations of particulate and respirable matter causing from dust storm in the air of Ilam city: cross sectional study

  Microbiology and Infectious Diseases

  Introduction: In recent years, dust storms frequently arrived to have large areas of the western half of Iran. Dust part...Read more

• Human reovirus destroys liver cancer cell line (Huh-7)

  Cancer; Prevention, Diagnosis and Treatment

  The Huh-7 cell line was derived from a liver tumor in a 57-year-old Japanese male patient in 1982. Hepatocellular carcin...Read more

• Apoptotic effect of anticancer drug Alimta on A549 calls is independent of HMGB1 release

  Cancer; Prevention, Diagnosis and Treatment

  Lung cancer is the leading cause of cancer-related deaths worldwide. Alimta is a new-generation antifolate drug, approv...Read more

• An in vitro study on the cytotoxicity of anticancer drug Mitoxantrone on hematopoietic stem cells of bone marrow

  Cancer; Prevention, Diagnosis and Treatment

  Mitoxantrone (Novantrone®; dihydroxyanthracenedione) is a synthetically designed antineoplastic agent and structurally ...Read more

• Antibacterial effects of curcumin encapsulated in micelle nanoparticles on mexX gene expression in ciprofloxacin resistant isolates of Pseudomonas aeruginosa in Guilan

  Nano-Biotech Medical

  Curcumin, a polyphenolic compound fromturmeric (Curcuma longa) is a pharmacologically safe agent that has antibacterial ...Read more

• Association between the CYP2E1 polymorphisms and CML risk in Iranian population

  Medical Genetics

  Polymorphism in the genes encoding detoxification enzymes results in variability to metabolize carcinogens and cause int...Read more

• Neural System Biomarkers

  Stem cell and Medical Applications

  Biomarkers are widely used by physicians, Labradoreans, and scientists. Popular utilization of biomarkers in vivo and in...Read more

• Design and evaluation of a colorimetric method for rapid determination of minimal inhibitory concentration of the bacteria belonging to Enterobacteriace

  Microbiology and Infectious Diseases

  Isolation of antibiotic resistant pathogenic bacteria in clinic may pose the serious problems. So a rapid method capabl...Read more

• Distribution of Main Variants in Reactions of Cytotoxin vacA of H. pylori in Gastric Biopsy Specimens

  Microbiology and Infectious Diseases

  Humans have suffered digestive problems for centuries, and we now know that H. pylori are one of their most important ca...Read more

• Preconditioning of bone marrow-derived mesenchymal stem cells by AdipoRon potentiates cell migration ability, in vitro.

  Stem cell and Medical Applications

  Mesenchymal stem cells (MSCs) have represented a great potential in recent stem cell-based therapies as well as regenera...Read more

• Thiolated chitosans development and in vitro evaluation of apermeation enhancing oral drug delivery system

  Nano-Biotech Medical

  This study investigated the in vitro release of Vancomycin and Amphotericin B fromnovel mocuadhesive chitosan nanofibers...Read more

• Detection of methylated DNA based on graphene quantum dot -DNA interaction

  Nano-Biotech Medical

  Epigenetics is the study of interaction between genes and their expressed product which is controlled by some specific c...Read more

• the review of The implications in toxicity Metabolomics of Delta9-tetrahydrocannabinol

  Metabolism and Metabolic Diseases

  The plant Cannabis sativa has been used for the effects of its psychoactive resins that name is (cannabinoid δ-9-tetrah...Read more

• Combinatorial therapy of anti-Treg vaccine associated with anti-tumor DC vaccine in mice tumor therapy

  Cancer; Prevention, Diagnosis and Treatment

  Regulatory T cells (Tregs) obviously have a crucial role in attenuation of anti-tumor immune responses. Application of r...Read more

• Effects of serotonin on adiponectin secretion and leptin gene expresions in rats

  Women and Reproductive Health

  Serotonin is a neurotransmitter which stimulates the secretion of sexual hormones . The nuclei of Hypothalamus involved...Read more

• Promoter Hypermethylation Analysis of the Tumor Suppressor Gene RASSF1A in Iranian Endometrial Carcinoma Patients

  Cancer; Prevention, Diagnosis and Treatment

  Endometrial cancer is the most common malignancy among women in developed countries. More endometrial cancers occurs in ...Read more

• Effect of EMF on Semen TBARS Concentration

  Women and Reproductive Health

  Electrical instruments in human life by development of applications causes new biological phenomenon in this century. Ne...Read more

• Evaluation of Catalase (CAT) expression in Acute Myeloid leukemia Patients

  Cancer; Prevention, Diagnosis and Treatment

  Acute myeloid leukemia is a heterogeneous neoplastic malignancy, that despite considerable progress in many of its molec...Read more

• In silico cancer therapy by using genome editing tool: CRISPR/Cas9

  Cancer; Prevention, Diagnosis and Treatment

  Given the fact that cancer today has a broad spectrum of diseases in the populations, and also by relying on the fact th...Read more

• One Step Toward Normal Heart Beat By Biological Pacemaker

  Medical Genetics

  Cardiac electrical impulses are generated in sinoatrial node (SAN) which establishes spontaneous action potentials. SAN ...Read more

• Cytotoxic effect of anticancer drug 5-Azacitidine on hematopoietic stem cells of bone marrow in the presence and absence of Colony stimulating factors

  Cancer; Prevention, Diagnosis and Treatment

  The cytosine analogue, 5-Azacitidine as a DNA methyltransferase inhibitor is currently considered the most advanced drug...Read more

• Blocking of vascular endothelial growth factor signaling through design of bi-specific single domain antibody

  Nano-Biotech Medical

  Over-expression of vascular endothelial growth factor (VEGF) leads to the proliferation and neovasculature of cancer cel...Read more

• Hydroxyapatite-Gelatin-bone marrow stromal cells construct as an excellent bone graft in animal model

  Stem cell and Medical Applications

  Bone healing of critical-sized defects are one of the most challenging orthopaedic problems. In the current study, the e...Read more

• Association between Heat shock protein 70 gene polymorphism and risk of multiple sclerosis in Iranian population

  Medical Genetics

  Multiple sclerosis (MS) is a chronic disease of the central nervous system and one of the most common causes of neurolog...Read more

• Survey of the Relationship between Two Polymorphisms at Position T677C and C1298A in MTHFR Gene with ADHD in Tehran Children

  Medical Genetics

  Attention deficit hyperactivity disorder is one of the most common behavioral disorders in children, which is associated...Read more

• Hox Genes in Malignant Hematopoiesis in Human- A review

  Medical Genetics

  Human beings have 39 HOX genes arranged in four clusters that are located on different chromosomes. These genes are an e...Read more

• Computer aide discrimination of the ovarian lesions by CT scan images

  Cancer; Prevention, Diagnosis and Treatment

  To explore diagnostic potential of computerizing texture analysis (TA) methods in discrimination of the normal, benign...Read more

• CLONING AND EXPRESSION OF an antibody fragment (scFv) against PcrV protein of Pseudomonas aeruginosa in fed-batch cultivation mode

  Microbiology and Infectious Diseases

  Pseudomonas aeruginosa is a major cause of hospital-acquired infections, particularly in mechanically ventilated patient...Read more

• Synergistic Antibacterial Activity of Zinc Oxide Nanoparticles with Cuminum cyminum L. Essential Oil against the Food-Borne Pathogens Salmonella enterica

  Nano-Biotech Medical

  One of the ways to control of pathogenic microorganisms in foods is to use preservatives and antimicrobial agents. Diffe...Read more

• Client's Attitude Towards legal and Ethical Aspects of Sperm Donation in a Health Center of Tehran

  Women and Reproductive Health

  Sperm donation is one of the technologies associated with infertility treatment. Some couples don't have any child due t...Read more

• Effect of Extract of Origanum Vulgare on the activity of alanine aminotransferase enzyme in healthy and diabetic mice

  Metabolism and Metabolic Diseases

  Wild Thyme is a great medicinal plant that grows in different areas of the Mediterranean and some parts of Asia.Present ...Read more

• The effects of minoxidil on gene expression in the bulb and bulge region of hair follicles by Real time-PCR

  Beauty

  Minoxidil is the most common drug used for treatment androgenic alopecia.Studies have shown that this drug can increase ...Read more

• Lipase adsorbtion on the single layer geraphene oxide dependes on pH and temperature

  Nano-Biotech Medical

  graphene oxide (GO) has been used as a matrix for lipase immobilization. GO chemical properties are reported beneficial ...Read more

• Toxic effects of Selenite and need to bio removal of it

  Nutrition and Health

  Selenium is an important micronutrient for human and animal health, however it is toxic slightly above homeostatic requi...Read more

• The Expression Profile of ERBB3 and Its Ligand NRG1 on Depressed Patients Investigation in Hormozgan

  Medical Genetics

  Major depressive disorder (MDD), also known simply as depression, is a mental disorder characterized can negatively affe...Read more

• NEW CONCEPTS IN THE IMMUNOPATHOGENESIS OF MULTIPLE SCLEROSIS

  Medical Genetics

  Multiple sclerosis (MS) is a chronic disorder of the central nervous system characterized by autoimmune inflammation, de...Read more

• miR-214 induces insulin resistance in C2C12 cell line though targeting Rock1 and Akt2 gene expressions

  Metabolism and Metabolic Diseases

  Micro-RNAs (miRNAs) are a class of post-transcriptional regulators that play crucial roles in various biological process...Read more

• Prognostic significance of c-Myc gene amplification and protein expression in brain tumors: Astrocytoma and meningioma

  Cancer; Prevention, Diagnosis and Treatment

  Astrocytoma and meningioma are the most common primary brain tumors. c-Myc as a member of MYC proto-oncogenes has recent...Read more

• The effect of ziziphora extract on the expression of the Claudin_1 gene in the AGS cell line

  Cancer; Prevention, Diagnosis and Treatment

  Claudins are the main structural and functional proteins of tight junctions in epithelial cells. The altered expression ...Read more

• Correlation between oral health status and salivary total antioxidant capacity in type 2 diabetes mellitus among Iranian adults

  Metabolism and Metabolic Diseases

  Diabetes mellitus is a chronic metabolic disease leading to several complications. Among these, dental caries are consid...Read more

• Skin anti-ageing potential of Lactobacilli exopolysaccharides (EPSs) on human fibroblast

  Beauty

  Skin aging is a complex biological process influenced by a combination of endogenous or intrinsic and exogenous or extri...Read more

• Non-muscle Myosin Heavy Chain 9 Gene (MYH9) Polymorphism (rs4821481) is Associated with Urinary Albumin Excretion in Iranian Diabetic Patients

  Medical Genetics

  Myosin heavy chain 9 (MYH9) gene polymorphisms have been implicated in a different type of renal disease as well as neph...Read more

• Investigating the role of exon7 axin2 in colorectal cancer (Laboratory and bioinformatics studies)

  Cancer; Prevention, Diagnosis and Treatment

  In Iran, colon cancer is the third most common cancer. WNT pathway changes are commonly reported in this cancer. Among t...Read more

• Study on protein of leech saliva of Hirudo Oreintalis, Utevsky & Trontelj 2005 in different ages

  Nutrition and Health

  Medicinal leech, during feeding, enter in host body many bioactive substances that often contain proteins and peptides. ...Read more

• Down-Regulation of Bcl-2 and Mcl-1 by MiRNA-15 and 16 Synergistically Enhances the Apoptotic Effects of ABT-199 and Fludarabin in CLL Cells

  Cancer; Prevention, Diagnosis and Treatment

  MiRNA-15 and 16 can act as a tumor suppressor gene by interfering with Bcl-2 and mcl-1. Studies have demonstrated that o...Read more

• Production of recombinant Streptococcal pyogenes exotoxin a protein

  Medical Genetics

  Exotoxin A is one of the toxins which produce by group a streptococcuses. This Toxin is a protein soluble substance whic...Read more

• TP53 hotspot mutations and expression of c-Myc oncogenes in astrocytoma and meningioma

  Medical Genetics

  Most studies have shown that there are association between the development and malignancy of brain tumors and tumor supp...Read more

• Electrospun PVA/PVP/chitosan Membrane with Controlled Release of Antibiotics for intraperiodontal pocket drug delivery

  Nano-Biotech Medical

  Gingivitis and periodontitis have become major public health problem in the world. Such growing incidence of periodontit...Read more

• ELISA Cross-Reactivity method to confirm recombinant fliC from salmonella typhimurium and evaluate impurities in purified recombinant protein

  Microbiology and Infectious Diseases

  Recombinant proteins as important materials for biomedicinal research, need high level of purity in order to be used in ...Read more

• Non-syndromic obesity in infertile men and structural chromosomal abnormalities

  Medical Genetics

  Obesity is commonly classified into subgroups depending on suspected etiology: monogenic obesity (extremely severe obesi...Read more

• Antimicrobial susceptibility of Acinetobacter baumannii isolated from different clinical samples in hospitalized patients

  Microbiology and Infectious Diseases

  Acinetobacter baumannii is a gram negative bacteria, which is cause multidrug-resistant nosocomial infection. Control an...Read more

• The effects of nano-liposomes containing curcumin on the lung cancer cell line.

  Nano-Biotech Medical

  Lung cancer is one of the most common and malignant cancer in both sexes. The prevalence and spread of cancer in iran an...Read more

• Apoptotic Effect of Tamoxifen on Hepatocellular Carcinoma Hep G2 Cell Line

  Cancer; Prevention, Diagnosis and Treatment

  Hepatocellular carcinoma (HCC) is the sixth most common cancer, and the third most common cause of cancer-related death...Read more

• Determination Of intestinal Escherichia coli Pathotypes Frequency in Tehran Province By PCR

  Microbiology and Infectious Diseases

  Escherichia coli (E.coli) is an important member of the normal intestinal microflora for mammals, including humans.Diarr...Read more

• Modeling premunition for parasites

  Microbiology and Infectious Diseases

  : Here we are interested in premunition that is an immunologic response in host which provides protection toward some pa...Read more

• Using micronuclei assay in cancer treatment

  Medical Genetics

  Cancer is one of the leading causes of illness and mortality worldwide, after cardiovascular disease. There are differen...Read more

• Design and cloning of tanatin peptide in Pichia.pastoris and evaluation of its antifungal activity

  Microbiology and Infectious Diseases

  Nowadays, control of fungal infections is one of the most important goals in the field of health. Therefore, developing ...Read more

• Study the expression rate of claudin-1 gene in Crocus sativus (saffron ) treated AGS cell lines

  Cancer; Prevention, Diagnosis and Treatment

  Claudins are the main structural and functional proteins of tight junctions in epithelial cells. The altered expression...Read more

• Molecular diagnosis of Mycoplasma spp. arthritis by PCR

  Microbiology and Infectious Diseases

  Arthritis is one of the most common inflammatory diseases. It is characterized by symptoms such as systemic inflammation...Read more

• The evaluation of recombinant beclin1 effect on cervical cancer in mice model

  Medical Genetics

  One of the factors that play a direct role in suppressing cancer cells is the pathway of autophagy and apoptosis that is...Read more

• Comparison of miR-605 expression in normal and tumor tissue samples of patients with colorectal cancer.

  Cancer; Prevention, Diagnosis and Treatment

  Colorectal cancer (CRC) is the third common type of cancer, and is considered as the main cause of cancer deaths in both...Read more

• Evaluation of Adiponectin Hormone in Diabetic and Non-diabetic Patients

  Metabolism and Metabolic Diseases

  Adipose tissue is currently considered as a hormonally active system in the control of metabolism and not only as a stor...Read more

• Relation between Resilience and Psychiatric Disorders in Patients with Aids in Bandar Abbas Center for Behavioral Diseases

  Nutrition and Health

  The AIDS process is very complex and can significantly affect the physical, social, spiritual and psychological health o...Read more

• Prognostic value of MSI status in colorectal cancer patients

  Cancer; Prevention, Diagnosis and Treatment

  Microsatellite instability (MSI) causes hereditary non-polyposis colorectal cancer (HNPCC), and occurs in about 15 per c...Read more

• Effect of Staphylococcus aureus isolates in food samples on hep2 cell line

  Microbiology and Infectious Diseases

  Staphylococcus aureus produces a range of protein-rich toxins and also extracellular pathogens that contribute to bacter...Read more

• Intervention of Dopamine D2 Receptors in Regulating the Serum Lipid Profile in Male Rats under Food Restrictions

  Nutrition and Health

  Studies have indicated that reduced energy consumption mostly has a significant effect on the reduction of blood lipids...Read more

• Braest cancer micrometastatic detection in sentinele lymph nodes using molecular marker

  Cancer; Prevention, Diagnosis and Treatment

  Breast cancer is prevalent malignancy among women in worldwide (1). Molecular diagnosis is recently proposed as a sensit...Read more

• Application of cold atmospheric plasma in human and veterinary medicine

  Microbiology and Infectious Diseases

  In the last few years plasma medicine has completed the transition from a field of research to actual evidence-based cli...Read more

• Discrimination of Leishmania species by Arginine permease gene AAP3as a suitable molecular tool for detection and genetic proximity analysis

  Microbiology and Infectious Diseases

  Leishmaniasis presents itself in different clinical manifestations such as: visceral Leishmaniasis, Cutaneous Leishmania...Read more

• Investigation of KLF1 gene and It's affection on thalassemia minor patients

  Medical Genetics

  : Thalassemia is a type of hereditary autosomal recessive disorder in which the existing genetic defect reduce the amoun...Read more

• Can air pollution impact of sperm parameters? A meta- analysis

  Women and Reproductive Health

  Air pollution is common in all countries and affects reproductive functions in men and women. It particularly impacts sp...Read more

• Curcumin regulates proinflammatory signaling function of thrombin in endothelial cells

  Microbiology and Infectious Diseases

  Curcumin regulates proinflammatory signaling function of thrombin in endothelial cells...Read more

• Sun protection factor (SPF) determination of sericin cream and niosomal gel

  Beauty

  Sericin is a protein extracted from silk and has antioxidant, antimicrobial, antineoplastic, wound healing and moisturiz...Read more

• Detection of Mycoplasma hyorhinis contamination in biological products by PCR method

  Microbiology and Infectious Diseases

  Mycoplasmas are the major contributors to biological products and cell lines throughout the world and are easily able to...Read more

• Effect of Velcade in Combination with Nanocurcumin in Breast Cancer 4T1

  Nano-Biotech Medical

  : It is well known that breast cancer has the highest incidence rates of about 30% of all types of cancer in women, and ...Read more

• Osteo therapy and the role of chitosan-alginate in osteoarthritis

  Nano-Biotech Medical

  Osteoarthritis (OA) is a progressive skeleton disturbance that it is usually related with considerable inability and lim...Read more

• Sensitivity of levofloxacin in combination with ampicillin-sulbactam and tigecycline against multidrug-resistant Acinetobacter baumannii

  Microbiology and Infectious Diseases

  During the last decades, emergence of antibiotic resistance among A. baumannii has been considered as a worldwide alarm....Read more

• Assessment of the dietary intake of Vitamin D and Blood pressure in Elderlies with health care

  Nutrition and Health

  Population studies have demonstrated that there is an inverse association between dietary intake of vitamin D and incide...Read more

• The Use of Viruses to Treat Cancer

  Cancer; Prevention, Diagnosis and Treatment

  Cancer is an abnormal growth of cells that have lost normal control mechanisms and are able to expand continuously, inva...Read more

• Assessment of energy and water-soluble vitamins intake in the elderly under health care, Isfahan, Iran

  Nutrition and Health

  The B vitamins are essential nutrients to maintain nutritionally healthy body. These water soluble vitamins are critical...Read more

• Rosmarinic acid, a Anti-glycation agent, inhibits protein glycation in vitro

  Metabolism and Metabolic Diseases

  Diabetes mellitus is one of the most non-communicable diseases and is the fifth leading causes of death in most of the d...Read more

• Prevalence of beta-lactam resistant isolates of Enterobacteriaceae in clinical specimens

  Microbiology and Infectious Diseases

  Background: The emergence of extended-spectrum beta-lactamase (ESBL) producing isolates of Enterobacteriaceae has impor...Read more

• The effect of aerobic training with pomegranate juice on glycemic control and lipid profile women with type 2 diabetes

  Metabolism and Metabolic Diseases

  Type 2 diabetes is a common metabolic disease, which is associated with obesity and immobility. The studies have shown t...Read more

• β-Cyclodextrin Modified Graphene Oxide Bionanocomposite for pH-sensitive Release of Anti-cancer Drug

  Nano-Biotech Medical

  Graphene is a multifunctional carbon nanomaterial and could be utilized to develop platform technologies for cancer ther...Read more

• Pharmacogenomics in Multiple sclerosis

  Medical Genetics

  Multiple sclerosis is a chronic inflammatory disease in the central nervous system. The most effective drugs for MS pat...Read more

• Rapid and cost effective method for the purification of DNA from Streptococcus mutans and other oral microorganisms

  Microbiology and Infectious Diseases

  Over 325 bacterial species have been cultured from dental plaque. Not all species can be cultured routinely. Thus, consi...Read more

• Molecular identification of Aspergillus isolated from livestock feed and poultry using ASAP1 sequencing

  Microbiology and Infectious Diseases

  The contamination of livestock feed and poultry with toxic fungi, such as aspergillus in the air and the environment, is...Read more

• MYH9 gene and urinary albumin excretion in Iranian diabetic patients

  Medical Genetics

  Diabetic nephropathy (DN) is one of the most common causes of end stage renal disease (ESRD).: Myosin heavy chain 9 (MYH...Read more

• Effect of Zinc nanoparticle on p53 expression in K562 cell line by Real Time PCR

  Medical Genetics

  Chronic myeloid leukemia is a cancer of blood which is identified by bcr/abl translocation. Imatinib is a tyrosine kinas...Read more

• Aloe Vera Herbal Effects on Diabetes Treatment and Prevention: A Systematic Review

  Metabolism and Metabolic Diseases

  Diabetes is one of the most common metabolic diseases that affects more than 150 million people in the world. It is the ...Read more

• evaluation of anti-mullerian hormone in daughters of women with polycystic ovary syndrome

  Women and Reproductive Health

  Polycystic Ovary Syndrome(pcos) is one of the most common endocrine diseases among women during their fertility years . ...Read more

• CRISPR/Cas9-mediated gene Knockout

  Cancer; Prevention, Diagnosis and Treatment

  Genome engineering is a novel and powerful tool for biotechnological applications. The development of the Clustered Regu...Read more

• Comparative study of Calendula officinalis and Matricaria chamomilla extracts on Cisplatin induced neuropathic pain

  Cancer; Prevention, Diagnosis and Treatment

  Cisplatin is one the most important cancer chemotherapy agents that uses for two decades. Neuropathic pain induced by th...Read more

• The Effects of MicroRNAs on Bone Regeneration and Differentiation

  Medical Genetics

  One of the promising approaches for osteoporosis treatment is bone regeneration. In this case, several therapeutic optio...Read more

• Biosynthesis of Silver nanoparticles using water extract of Ziziphus spina_cheristi Leaves

  Nano-Biotech Medical

  Silver nanoparticles (AgNPs) have been widely used as an antiseptic against a wide range of microorganisms. The goal of ...Read more

• Explaining Women's Views on Cervical Cancer: A Qualitative Study

  Cancer; Prevention, Diagnosis and Treatment

  Cervical cancer is the second most common cancer in the world , Which, if detected and treated at early stages, is almo...Read more

• Evaluation of serum lipid profiles and oxidative stress indices in sprayer workers

  Metabolism and Metabolic Diseases

  Direct or indirect contact with pesticides and toxins leads to some biochemical changes, including increasing the produc...Read more

• Shedding light on new form of combination therapy in acute promyelocyte leukemia

  Cancer; Prevention, Diagnosis and Treatment

  Although physicians have taken a variety approaches for the treatment of acute promyelocytic leukemia (APL), there is no...Read more

• Managing The Abnormal Papsmear In Pregnancy

  Cancer; Prevention, Diagnosis and Treatment

  Cervical cancer is the most common malignancy diagnosed during pregnancy . The incidence of abnormal pap smear in pregna...Read more

• BRCC2 gene inhibits lung cancer cell proliferation and invasiveness in vitro and in vivo:Prospect for gene therapy

  Cancer; Prevention, Diagnosis and Treatment

  Lung cancer is one of the major causes of cancer related death worldwide .Despite recent improvements, resistance to con...Read more

• Genotyping of Escherichia coli strains isolated from hospitals sewage

  Microbiology and Infectious Diseases

  Today one of the most common problems in the health society is the way of treating multidrug resistant (MDR) organisms. ...Read more

• Medicinal plants in the treatment of infertility

  Women and Reproductive Health

  Infertility is disability of a couple to reach pregnancy for more than one year despite regular sexual intercourse. The ...Read more

• Some candidate Biomaterials for Amniotic Membranes (AM) Regeneration: a review

  Stem cell and Medical Applications

  Amniotic Membranes (AM) wich form the amniotic sac filled by amniotic fluid and completely surrounds the embryo/fetus. I...Read more

• Identifying Linking Mechanisms of Allergy and Cancer

  Cancer; Prevention, Diagnosis and Treatment

  Allergy and cancer are prevalent diseases and cause a lot of morbidity and mortality. In recent years, many studies have...Read more

• The effect of mouse recombinant resistin on blood- brain barrier permeability, MDA content and apoptosis in the early stages of focal cerebral ischemia in a stroke mouse model

  Metabolism and Metabolic Diseases

  The aim of this study was to evaluate the dose-dependent effects of mouse recombinant resistin on blood-brain barrier(BB...Read more

• Investigation of microRNAs involved in the EGFR molecular pathway as a biomarker in early detection of colorectal cancer

  Medical Genetics

  Colorectal cancer (CRC) is one of the most common cancers in the world. The highest incidence of CRC in Europe, North Am...Read more

• The prevalence of adeABC encoding genes among Acinetobacter baumannii carbapenem resistant clinical isolates.

  Microbiology and Infectious Diseases

  Acinetobacter baumannii is the important cause of nosocomial infections worldwide due to its propensity to rapidly acq...Read more

• T cell engineering for cancer imenuterapy

  Cancer; Prevention, Diagnosis and Treatment

  With regard to the prevalence of cancer in the world, treatment have become important. One of the methods is to stimula...Read more

• Survaey polymorphism rs 866751883 ADAM2 gene infertile men referred to infertility treatment centers in East Azerbaijan which under treatment with IUI (Intrauterine Insemination)

  Medical Genetics

  One of the most important genes in human infertility is ADAM2 gene. The gene function is the important in the process of...Read more

• Canavan disease: clinical and molecular review

  Medical Genetics

  Canavan disease is a rare autosomal recessive disorder that predominantly affects the central nervous system with white ...Read more

• Autism spectrum disorder (ASD) and cancer: both share same genes but different outcomes.

  Medical Genetics

  Autism spectrum disorder (ASD) is a neurodevelopmental disorder and it is characterized by social and communication prob...Read more

• Investigation the effect of low intensity pulsed ultrasound (LIPUS) on proliferation of G 292 osteosarcoma cells on 3D porous PLGA/β-TCP scaffold within perfusion bioreactor

  Stem cell and Medical Applications

  Investigation the effect of low intensity pulsed ultrasound (LIPUS) on proliferation of G 292 osteosarcoma cells on 3D p...Read more

• Design, synthesis and application of conjugated gold nanoparticles in photodynamic therapy

  Nano-Biotech Medical

  Photodynamic therapy (PDT) has been developed as a novel method for cancer therapy. PDT involves the combined use of a p...Read more

• Application of stem cells in modern therapeutic methods

  Stem cell and Medical Applications

  Stem cells are one of the modern therapies being used over recent years to treat diseases such as repairing damaged hear...Read more

• Additive Cytotoxic Effect of Apoptin and Chemotherapeutic Agent Docetaxel on LNCaP Cell Lines

  Cancer; Prevention, Diagnosis and Treatment

  Unfortunately although chemotherapy is primary therapy for most types of advanced prostate cancer, conventional chemothe...Read more

• Detection of Borrelia microti in blood samples spotted on DNA Banking Card by using Loop-Mediated Isothermal Amplification (LAMP)

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