Mahdieh Salimi*
National Institude of Genetic Engineering and BiotechnologyTehran, Tehran
Abstracts, [Author]
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Comparison of miR-605 expression in normal and tumor tissue samples of patients with colorectal cancer.
Cancer; Prevention, Diagnosis and TreatmentColorectal cancer (CRC) is the third common type of cancer, and is considered as the main cause of cancer deaths in both...Read more
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Molecular monitoring of Chronic Myeloid Leukemia in Chronic Phase (CML-CP)
Medical GeneticsQuantification of the BCR-ABL transcript is recommended to follow-up CML patients that treated by Imatinib mesylate (IM)...Read more
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Genes involved into both alternative splicing and aging pathways as biomarkers for Parkinson Disease diagnosis
Medical GeneticsParkinson's Disease is a degenerative movement disorder that exhibit symptoms through progressive loss of dopaminergic...Read more
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Toll-like receptor 4 mediates cross-talk between peroxisome proliferator-activated receptor γ and nuclear factor-κB in mouse melanoma (B16F10) in vitro
Cancer; Prevention, Diagnosis and TreatmentThere is increasing evidence that chronic activation of nuclear factor-κB (NF-κB), which is an essential signaling pat...Read more
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Isolation and identification of probiotic bacteria from human milk
Microbiology and Infectious DiseasesBackground: Breast milk is the best nutritional supplement during the first few months of the baby's life. It contains v...Read more
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The relationship between TPH1 (rs1800532) and TPH2 (rs4570625) polymorphisms in type 1 bipolar patients compared with healthy subjects
Medical GeneticsBipolar disorder has episodes of depression and mania or hypomonia. several serotonin-associated genes correlated with S...Read more
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Preconditioning of bone marrow-derived mesenchymal stem cells by AdipoRon potentiates cell migration ability, in vitro.
Stem cell and Medical ApplicationsMesenchymal stem cells (MSCs) have represented a great potential in recent stem cell-based therapies as well as regenera...Read more
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Self-Concept among Infertile women receiving oocyte donation and Fertile Women
Women and Reproductive HealthOne of the technologies used to assist fertility is oocyte donation. Although there is sufficient information about med...Read more
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Investigation of antioxidant capacity of silver nanoparticles with Laurencia caspica seaweed on liver cancer cell line (HepG2)
Nano-Biotech MedicalHepatocellular carcinoma is a type of hepatocellular carcinoma that occurs most often in cases of hepatitis B and C, or ...Read more
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Additive Cytotoxic Effect of Apoptin and Chemotherapeutic Agent Docetaxel on LNCaP Cell Lines
Cancer; Prevention, Diagnosis and TreatmentUnfortunately although chemotherapy is primary therapy for most types of advanced prostate cancer, conventional chemothe...Read more
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Marine Biotechnology in public health and food safety
Nutrition and HealthSea and oceans make up more than 70 percent of the Earth's surface, and on the other hand, more than 80 percent of livin...Read more
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Investigating the absorption of anti-cancer drugs on the surface of the boron nitride nano cage by the dense function theory
Nano-Biotech Medicalmagesterol is a drug used in the treatment of breast and endometrial cancer. Due to the unwanted side effects of this dr...Read more
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Investigating the presence of chemical compounds in pineapple
Cancer; Prevention, Diagnosis and TreatmentPineapple is a member of the Ananasian family, it is a sub-tropical fruit. It has many chemical compounds that are impor...Read more
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The Study of the Frequency of Antibiotic Usage as an Important Factor in Appearing Antibiotic Resistance in All of the Units in Namazi Hospital
Microbiology and Infectious DiseasesAs the unusual increase in using antibiotics has been suggested as an indicative factor in appearing antibiotic resistan...Read more
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Study of DNA methylation pattern in sf-1 gene promoter region in endometriosis tissue samples of women in north west of Iran
Medical GeneticsEndometriosis is an estrogen-dependent inflammatory disease. Its defining feature is the presence of endometrium-like ti...Read more
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A Turn-Off Fluorescent Sensor Based On Carbon Dots for Sensitive Detection of Tetracycline in Milk
Nutrition and HealthThe detection of tetracycline in animal-derived food and drug is very significant, because of its harmful effects on hum...Read more
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Synthesis of pH-sensitive micelles based on F127-Dox conjugated for drug delivery to cancer cells
Nano-Biotech MedicalA variety of nano-systems constituted by polymer–drug conjugates have been designed to overcome its shortages on water...Read more
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Apoptotic and cytotoxic effect of the thiosemicarbazone complex with Zn2+ in K562 cell line
Cancer; Prevention, Diagnosis and TreatmentThiosemicarbazone family is organic compounds with antitumor, antibacterial and antiviral effects. In the present stud...Read more
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Effects of Rosmarinic acid on oxidative stress and total antioxidant capacity in vivo study
Metabolism and Metabolic DiseasesDiabetic disease is characterized by chronic hyperglycaemia. Numerous studies have shown that in diabetes mellitus, ther...Read more
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The Role of Viral Proteins VP24 and VP35 in The Pathogenesis of The Ebola Virus
Microbiology and Infectious DiseasesThe Ebola virus is a member of the Filoviridae family, which is causing hemorrhagic and fatal fever to humans. Ebola is ...Read more
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Recent study about Genetics of Human Obesity
Medical GeneticsObesity has become a global epidemic and contributes to the increasing burden of type 2 diabetes, cardiovascular disease...Read more
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The evaluation of recombinant beclin1 effect on cervical cancer in mice model
Medical GeneticsOne of the factors that play a direct role in suppressing cancer cells is the pathway of autophagy and apoptosis that is...Read more
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Evaluation of Interleukin 10 Gene Promoter Polymorphisms of -592A/C and -1082A/G Region Among Obese Individuals with Type 2 Diabetes in Alborz Province
Metabolism and Metabolic DiseasesToday diabetes is one of the most prevalent noncontagious diseases around the world. There is strong evidence showing in...Read more
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the effect of Lactobacillus acidophilus (La) and Lactobacillus rhamnosus (Lr) on proliferation and invasion of Colorectal cancer cells (Caco2).
Cancer; Prevention, Diagnosis and TreatmentColorectal cancer is one of the most common epithelial cancers in the world. Many studies have been conducted on the inh...Read more
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Medicinal plants in the treatment of infertility
Women and Reproductive HealthInfertility is disability of a couple to reach pregnancy for more than one year despite regular sexual intercourse. The ...Read more
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Investigation efflux pump -activated fluoroquinolone resistance in pseudomonas aeroginosa multi drug resistance isolates by CCCP inhibitor
Microbiology and Infectious DiseasesPseudomonas aeruginosa is the third cause of nosocomial infections after Staphylococcus aureus and E. coli .One of the p...Read more
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Investigation of deaths caused by cancer in Bandar Anzali in 2014
Cancer; Prevention, Diagnosis and TreatmentCancer is one of the main causes of death and disability in Iran and the world. This study was conducted to evaluate the...Read more
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Intelligent Stimuli Responsive Core@Sell Nanobiomaterial: Biomedical Opportunities and Challenges
Nano-Biotech MedicalNanoscale objects are powerful devices in biotechnology medicine and biomedical sciences. They are potential applicants ...Read more
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THE TOLE OF PROBIOTICS IN PUBLIC HEALTH
Nutrition and HealthIn the last decade, we have seen dramatic changes in understanding the role of foods in improving human health. scientif...Read more
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Fast detection of Pseudomonas aeruginosa keratitis by Polymerase Chain Reaction (PCR)
Microbiology and Infectious DiseasesPseudomonas aeruginosa is an opportunistic pathogen that has different virulence factors. This organism is commonly foun...Read more
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Association of selenoprotein S expression and its variants with metabolic syndrome in subjects with cardiovascular disease
Metabolism and Metabolic DiseasesSelenoproteins S (SELS or VIMP) may regulate cytokine production, and thus play a key role in the control of the inflamm...Read more
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The effect of Bioactive glass on Adipose-derived MSC osteogenesis in 3D cultures
Stem cell and Medical ApplicationsRegenerative medicine is an emerging field of biotechnology that combines various aspects of medicine, cell and molecula...Read more
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Effect of Zinc Oxide Nanoparticles on expression of proapoptotic BAX and Bcl-2 in Testicular Tissue of NMRI Adult Mice
Nano-Biotech MedicalZinc oxide nanoparticles have numerous applications in medicine and industry. These materials are delivered to the tissu...Read more
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Frequency and Pattern of Resistance of AmpC-Beta-lactamase gene in Clinical isolates of Klebsiella pneumoniae from Zahedan Educational Hospitals
Microbiology and Infectious DiseasesThe detection of CTX-M-15 genes in ESBLs produced by Klebsiella pneumoniae strains provides useful information on epidem...Read more
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Effect of Zinc nanoparticle on p53 expression in K562 cell line by Real Time PCR
Medical GeneticsChronic myeloid leukemia is a cancer of blood which is identified by bcr/abl translocation. Imatinib is a tyrosine kinas...Read more
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Infections Associated with Bacterial Biofilms and Treatment Problems
Microbiology and Infectious DiseasesMicrobial biofilms are seen in 65% of human infections. Bacteria in biofilms society are resistant against antibiotics. ...Read more
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The effect of diet in preventing of colorectal cancer: A systematic Review
Cancer; Prevention, Diagnosis and TreatmentColorectal cancer (CRC) is the third most commonly diagnosed cancer in worldwide and it is established that diet has an ...Read more
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Phylogenetic and Bioinformatics analysis of Interferon beta-1 Protein
Medical GeneticsInterferon beta-1b protein is used to improve MS disease and reduce the number of attacks in patients. The purpose of th...Read more
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Impact of GSTP1 genetic polymorphisms on susceptibility risk of chronic myeloid leukemia
Cancer; Prevention, Diagnosis and TreatmentGenetic variation influencing individual susceptibility to chemical carcinogens is one of the main factors leading to ca...Read more
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Investigating the incidence of cardiovascular in patients with ercutaneous coronary interventionin Bandar Abbas Shahid Mohammadi Hospital
Metabolism and Metabolic DiseasesPCI(Percutaneous coronary intervention) is one of the most common mode of re vascularization. so According to the impo...Read more
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Effect of Velcade in Combination with Nanocurcumin in Breast Cancer 4T1
Nano-Biotech Medical: It is well known that breast cancer has the highest incidence rates of about 30% of all types of cancer in women, and ...Read more
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Identifying MicroRNA-mRNA regulatory network in breast cancer sample with drug resistance
Cancer; Prevention, Diagnosis and TreatmentA computational approach to prediction of miRNA targets narrowing down potential target sites for experimental validatio...Read more
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Dietary intake of antioxidants in elderly: A case-control study in Iran
Nutrition and HealthNutrient deficiencies such as antioxidants are common problems in elderly subjects which can result in different cancers...Read more
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Study of HER2 gene expression in AGS cell line after treatment of cells with Crocus sativus (Iranian Saffron) extract
Cancer; Prevention, Diagnosis and TreatmentThe study of HER-2 gene in cancers, especially gastric cancer, is of great importance. This gene, has been shown to inc...Read more
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Molecular mechanism of alpha-2 adrenergic receptors in locus Coeruleus
Medical GeneticsPain is one of the most common forms of psychological stress and the most common phenomenon in medical science. Analgesi...Read more
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The Role of Nanobiotechnology in Identification and Treatment Lung Cancer
Nano-Biotech MedicalNanotechnology is the engineering of functional systems at the molecular scale. Therefore, it is possible to combine nan...Read more
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Evaluation of Adenovirus in Pseudomonas aeruginosa susceptible keratitis by PCR molecular method
Microbiology and Infectious DiseasesKeratitis is inflammation of the cornea of the eye. In keratitis, microbial agents are important. In the presence of inf...Read more
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Structural Study of Lysozyme upon Interaction with Plasmonic gold Nanoparticles
Nano-Biotech MedicalRecent advances in nanotechnology have encouraged scientists to design hybrid systems of nanoparticles and biological ma...Read more
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Investigation of Lead and Chromium Elements in Female Patients with Breast Cancer Before and After Chemotherapy
Cancer; Prevention, Diagnosis and TreatmentHeavy metals such as lead and chromium can be in various forms, including free ions, metal compounds or carcinogenic par...Read more
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EFFECT OF CHRYSIN NANO-PARTICLES TREATMENT ON ESTROGEN RECEPTORS EXPRESSION LEVELS IN BREAST CANCER CELL LINE
Nano-Biotech MedicalBreast cancer (BC) is increasing in the developing countries. Estrogens are supposed to play roles in BC initiation and ...Read more
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Bioinformatics evaluation of hsa-miR-548g related to single nucleotide polymorphism (rs1803622) of GAPDH gene in patients suffering from breast cancer
Cancer; Prevention, Diagnosis and TreatmentBreast cancer is one of the most prevailing cancer among females. GAPDH gene is located on chromosome l on position of G...Read more
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BsmI (rs1544410) polymorphism of vitamin D receptor gene modulates improvement of vitamin D status in overweight women with hypovitaminosis D
Nutrition and HealthThe aim of the present study was to evaluate the possible influence of BsmI (rs1544410) polymorphism of vitamin D recept...Read more
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Down-Regulation of Bcl-2 and Mcl-1 by MiRNA-15 and 16 Synergistically Enhances the Apoptotic Effects of ABT-199 and Fludarabin in CLL Cells
Cancer; Prevention, Diagnosis and TreatmentMiRNA-15 and 16 can act as a tumor suppressor gene by interfering with Bcl-2 and mcl-1. Studies have demonstrated that o...Read more
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Optimization of the best concentration of Aloe vera extract for treating gastric cancer cells in order to reduce HER-2 gene expression
Cancer; Prevention, Diagnosis and TreatmentHER2 is a glycoprotein that has tyrosine kinase activity and plays an important role in guiding growth signals. Its expr...Read more
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Anti-cancer effect of redroot pigweed as weed plant species
Cancer; Prevention, Diagnosis and TreatmentLeukemia cancer is currently one of the major causes of cancer-related deaths among humans. Extracts of plants including...Read more
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Antimicrobial susceptibility of Acinetobacter baumannii isolated from different clinical samples in hospitalized patients
Microbiology and Infectious DiseasesAcinetobacter baumannii is a gram negative bacteria, which is cause multidrug-resistant nosocomial infection. Control an...Read more
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Epigenetic Mechanisms as Therapeutic Targets
Medical GeneticsEpigenetics, in conjunction with genetic mechanisms, determine the biological fate of cells and living organisms. epig...Read more
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CRISPR/Cas9-mediated gene Knockout
Cancer; Prevention, Diagnosis and TreatmentGenome engineering is a novel and powerful tool for biotechnological applications. The development of the Clustered Regu...Read more
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Induction of apoptosis by silibinin in SKBR3 breast cancer cell line through activation of caspase 3/7
Cancer; Prevention, Diagnosis and TreatmentThe poor prognosis of breast cancer is due to its resistance to the conventional treatments. Therefore, researchers are ...Read more
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Effect of EMF on Semen TBARS Concentration
Women and Reproductive HealthElectrical instruments in human life by development of applications causes new biological phenomenon in this century. Ne...Read more
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An investigation on the structure and function of the cell surface lung-specific antigens for development a new generation of immunotoxins
Cancer; Prevention, Diagnosis and TreatmentLung cancer, with common symptoms such as coughing, weight loss and shortness of breath, is a disease via uncontrolled g...Read more
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An innovative field of plasma application for medical therapy
Microbiology and Infectious DiseasesPlasma medicine is an innovative and emerging field combining plasma physics, life science and clinical medicine. Recent...Read more
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Silencing of Mcl-1 and Bcl-2 by miR-15 Induces Apoptosis and Increases the Chemosensitivity of the CLL Cells
Cancer; Prevention, Diagnosis and TreatmentDespite advances in cancer therapy, drug resistance is a major problem in leukemia. Overexpression of anti-apoptotic pro...Read more
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Study of properties of Juglans regia plant on women’s health
Women and Reproductive HealthJuglans regia plant is one of Iranian native plants that some of it’s productive types are in Markazi province. The b...Read more
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3D Graphene Framework: A High-Performance Adsorbent for Antibiotics
Nutrition and HealthAntibiotics have been considered as emerging pollutants due to their continuous input and persistence in the aquatic eco...Read more
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Identification of bacterial agents of urinary tract infection in patients referred to a laboratory during six months
Microbiology and Infectious DiseasesEstablishing a diagnosis of symptomatic UTI requires a patient to have symptoms and signs of a UTI and laboratory tests ...Read more
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Investigating the specificity of the specific lytic bacteriophage against Salmonella bacteria and its effect on the hep2 cell line
Microbiology and Infectious DiseasesResistance to antibiotic treatments is one of the increasing problems. Therefore, alternative methods to reduce antibiot...Read more
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A genetic variant in Multiple drug resistance gene is associated with poor prognosis of patients with esophageal squamous cell carcinoma
Cancer; Prevention, Diagnosis and TreatmentEsophageal squamous cell carcinoma (ESCC) is one of the causes of death from cancer. Several genetic variants in the 7q2...Read more
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The study of Apolipoprotein E4 allele distribution in parents of Down's syndrome children as a risk factor in Iran
Medical GeneticsDown syndrome(DS) is the most common chromosomal abnormality.The most important factor in DS is increased maternal age s...Read more
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Evaluation of Catalase (CAT) expression in Acute Myeloid leukemia Patients
Cancer; Prevention, Diagnosis and TreatmentAcute myeloid leukemia is a heterogeneous neoplastic malignancy, that despite considerable progress in many of its molec...Read more
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Food Patterns and Framingham Risk Score in Iranian Adults: Tehran Lipid and Glucose Study: 2005-2011
Nutrition and HealthHealthy dietary habits can prevent cardiovascular diseases (CVD). The aim of the present study was to investigate the as...Read more
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Shedding light on new form of combination therapy in acute promyelocyte leukemia
Cancer; Prevention, Diagnosis and TreatmentAlthough physicians have taken a variety approaches for the treatment of acute promyelocytic leukemia (APL), there is no...Read more
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Nanodispersion-loaded mucoadhesive polymeric inserts for ocular drug delivery: scale up production
Nano-Biotech MedicalFrequent use of highly concentrated solutions may induce toxic side effects and cellular damage at the ocular surface. T...Read more
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Association of umbilical coiling index with hypothyroidism and gestational diabetes mellitus.
Metabolism and Metabolic DiseasesGestational diabetes mellitus [GDM] and hypothyroidism are prevalent and potentially serious condition which may put mot...Read more
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Anticancer effect of Quercus infectoria aqueous leaf extracts against colon cancer HT29 cell line
Cancer; Prevention, Diagnosis and TreatmentIn traditional medicine and previous studies, Quercus infectoria plants are a well-known and have been suggested as a ca...Read more
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The cultural, ethical and religious challenges of society related to assisted reproductive techniques
Women and Reproductive HealthInfertility is a worldwide problem of high prevalence of reproductive health. Significant advances in assisted reproduc...Read more
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miR-214 induces insulin resistance in C2C12 cell line though targeting Rock1 and Akt2 gene expressions
Metabolism and Metabolic DiseasesMicro-RNAs (miRNAs) are a class of post-transcriptional regulators that play crucial roles in various biological process...Read more
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Investigating the Verification of the Personnel Hand Hygiene Dividedly among Five Situations in Intensive Working in Namazi Hospital of Shiraz
Microbiology and Infectious DiseasesHand hygiene behavior divides into two categories: the innate hand hygiene and the selective hand hygiene. The innate ha...Read more
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Determination of antibiotic-resistant strains of isolated Brucella in Markazi Province
Microbiology and Infectious DiseasesBrucellosis is one of the common diseases of man and animals are caused by bacteria of the genus Brucella. The purpose o...Read more
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The Relationship between STR-PCR Chimerism Analysis and Chronic GvHD Following Hematopoietic Stem Cell Transplantation
Cancer; Prevention, Diagnosis and TreatmentGraft-versus-host disease (GvHD) is one of the serious complications of HSCT. Its prevalence has been reported as 20-50 ...Read more
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The role of artificial intelligence in medical decisions
Nano-Biotech MedicalThe term "artificial intelligence" was used in 1956. There is still no definitive definition of artificial intelligence ...Read more
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the role of genetics in diabetes and its complications
Medical GeneticsThe purposes of writing this article are the significant role of genetics in the onset of diabetes, hoping to be treated...Read more
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Constructing a Novel Hypoxia-Inducible Bidirectional shRNA Expression Vector for Simultaneous Genes Silencing in Colorectal Cancer Gene Therapy
Cancer; Prevention, Diagnosis and TreatmentBackground: RNA interference (RNAi) is an efficient genetic approach in gene-specific knockdown and gene therapy; howeve...Read more
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Chimeric Antigen Receptors (CARs) as a powerful approach for cancer therapeutics
Cancer; Prevention, Diagnosis and TreatmentT-cells have the potential to extirpate abnormal cells. The genetic modification and characterization of T-cells with ch...Read more
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Effect of marjoram extract on sperm concentration and its survival percentage in oxidative-cadmium stress in adult male rats
Nutrition and HealthNutrition Safety and Health is one of the important factors in fertility.Cadmium as an environmental pollutant by free r...Read more
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Analysis of hypermethylation of NFK-B ،TRAF1 and TRAF2 genes in patients with oral squamous cell carcinoma
Medical GeneticsCancer is a fatal disease caused mainly by environmental factors that mutate genes encoding critical cell-regulatory pr...Read more
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Investigating th expression of E-cadherin gen among patients suffering from stomach cancer in West Azerbaijan province
Medical GeneticsGastritis Cancer is one of the general death causes of cancer all over the world. According to the results of the resea...Read more
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Preparation and optimization of chitosan nanoparticles containing vancomycin
Nano-Biotech MedicalRecently, some novel drug delivery systems were designed to control drug release. The using of polymeric nanoparticles a...Read more
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Review: ASD heritability
Medical GeneticsAutism Spectrum Disorder (ASD) is one of the most common neurodevelopmental disorders; due to its high occurrence rate a...Read more
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Tamoxifen-induced rapid death of GPER positive cell lines by modulating RAS/MAPK signaling pathway
Cancer; Prevention, Diagnosis and TreatmentBreast cancer is the most common cancer in women worldwide. Tamoxifen is a nonsteroidal selective estrogen receptor modu...Read more
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Enrichment analysis of hsa-miR-320b-1 most related pathways in cancer
Cancer; Prevention, Diagnosis and TreatmentIntroduction: Cancer is a complex disease in which the expression of the gene is unbalanced. MicroRNAs are a group of no...Read more
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Synergistic Antibacterial Activity of Zinc Oxide Nanoparticles with Cuminum cyminum L. Essential Oil against the Food-Borne Pathogens Salmonella enterica
Nano-Biotech MedicalOne of the ways to control of pathogenic microorganisms in foods is to use preservatives and antimicrobial agents. Diffe...Read more
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Study the expression rate of claudin-1 gene in Crocus sativus (saffron ) treated AGS cell lines
Cancer; Prevention, Diagnosis and TreatmentClaudins are the main structural and functional proteins of tight junctions in epithelial cells. The altered expression...Read more
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Characterization of a carboxypeptidase inhibitor peptide isolated from Iranian scorpion venom glands cDNA library: a good candidate for cancer therapy
Cancer; Prevention, Diagnosis and TreatmentFinding a safe strategy for targeting tumor cells without affecting normal cells is one of the goals of cancer treatment...Read more
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study of promoter methylation status of pax5 gene in patients with gastric cancer
Cancer; Prevention, Diagnosis and TreatmentGastric cancer is the fifth leading cause of cancer and is also the third leading cause of death in the world .Although ...Read more
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A Review Article on Treatment with Stem Cells: Complications and Problems
Stem cell and Medical ApplicationsNowadays, various methods of treatment with stem cells are developing fast while such treatments have different and some...Read more
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Investigating the Relationship between Polymorphism of p22phox in Smoker Population with Chronic Obstructive Pulmonary Disease (COPD) and Susceptibility to Disease
Medical GeneticsCOPD (chronic obstructive pulmonary disease) is a slowly progressive condition characterized by airflow limitation, whic...Read more
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Rosmarinic acid, a Anti-glycation agent, inhibits protein glycation in vitro
Metabolism and Metabolic DiseasesDiabetes mellitus is one of the most non-communicable diseases and is the fifth leading causes of death in most of the d...Read more
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In silico epitope prediction and modeling for agent of smallpox and molecular docking for epitope-MHCⅠ receptor
Medical GeneticsAlthough Variola and Vaccinia viruses have been Eradicated but still smallpox can be a serious problem for Societies. H3...Read more
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Identifying Linking Mechanisms of Allergy and Cancer
Cancer; Prevention, Diagnosis and TreatmentAllergy and cancer are prevalent diseases and cause a lot of morbidity and mortality. In recent years, many studies have...Read more
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Evaluating the genetic variations in functional domains coding regions of MSMB in infertile men with unexplained infertility
Medical GeneticsΒ-Microseminoprotein(MSMB) is one of the most abundant proteins in human seminal plasma. This protein binds to head and...Read more
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Atopic Dermatitis and treatment
Nutrition and Health• diagnostic criteria Atopic dermatitis is difficult to define because of its variable morphology and distribution an...Read more
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Effect of LPS on regulatory T cell induction in peripheral blood mononuclear cells of endometriosis patients
Women and Reproductive HealthEndometriosis is an estrogen-dependent chronic inflammatory disease affecting women of reproductive age. Regulatory T ce...Read more
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An Evaluation of Tissue Destruction Time in Phrenic Nerve after Death and Counting the Number of Nerve Fibers in C3, C4 and C5 Branches
Cancer; Prevention, Diagnosis and Treatmentمقدمه اعصاب فرنیک چپ و راست، محرک اصلی عضلة دیافراگم میباشند( .)5ای...Read more
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Ischemia-modified albumin as an oxidative stress biomarker in acute coronary syndrome
Metabolism and Metabolic DiseasesFree radicals increasing or Antioxidants decreasing may contribute to impair the equilibrium between oxidant and antioxi...Read more
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Hydroxyapatite-Gelatin-bone marrow stromal cells construct as an excellent bone graft in animal model
Stem cell and Medical ApplicationsBone healing of critical-sized defects are one of the most challenging orthopaedic problems. In the current study, the e...Read more
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Molecular detection of factor 5 Leiden (G1691A) and its relation with TNF- α gene polymorphism in human abortion
Medical GeneticsAbortion is the most common of pregnancy complications. In the pathogenesis of abortion as a multifactorial disease, gen...Read more
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Therapeutic effect of Human Tumor Necrosis Factor Receptor-2 on collagen -induced arthritis in Balb/c mice
Metabolism and Metabolic DiseasesRheumatoid arthritis (RA) is a chronic, systemic, immune-mediated inflammatory disease associated with decreased life ex...Read more
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Comprehensive databank of Iranian patients with Noonan syndrome
Medical GeneticsNoonan syndrome (NS) (OMIM 163950) considered as a relatively common (1/1000-2500), developmental, multi-organ and compl...Read more
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Toxoplasmosis infection in the pregnant women in the first trimester in yasouj city
Women and Reproductive HealthToxoplasmosis is a shared human-animal disease with worldwide distribution caused by Toxoplasma gondii. More than half o...Read more
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Determining the Interactions between Major Dietary Patterns and LRP5 Genotypes (rs556442) on Bone Discordance in Postmenopausal Women Referred to Shariati Hospital
Nutrition and HealthOne of the challenges in the diagnosis of osteoporosis is bone discordance. Many studies have confirmed an association ...Read more
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Antibacterial properties of saffron
Microbiology and Infectious DiseasesSaffron is a small herb of the Welsh family. This is a plant with spherical onions which surrounded by a brown membrane....Read more
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Blood porphyrin fluorescence peaks and its diagnostic value for early colorectal cancer (CRC) detection
Cancer; Prevention, Diagnosis and TreatmentPorphyrins are precursors of Heme metabolism. Any metabolic disorder like cancer can highly affect their level. Since th...Read more
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Endurance training resulted in significantly greater betatrophin responses compared with resistance training alone, and resistance and endurance exercises combined
Metabolism and Metabolic DiseasesBetatrophin, which recently identified, is a liver and adipose tissue produced hormones that regulates the level of lipi...Read more
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Combinatorial therapy of anti-Treg vaccine associated with anti-tumor DC vaccine in mice tumor therapy
Cancer; Prevention, Diagnosis and TreatmentRegulatory T cells (Tregs) obviously have a crucial role in attenuation of anti-tumor immune responses. Application of r...Read more
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Apoptotic effect of anticancer drug Alimta on A549 calls is independent of HMGB1 release
Cancer; Prevention, Diagnosis and TreatmentLung cancer is the leading cause of cancer-related deaths worldwide. Alimta is a new-generation antifolate drug, approv...Read more
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Comparison of in vitro survival of mononuclear cells derived from B-CLL patients with or without BAFF & APRILL cytokines
Cancer; Prevention, Diagnosis and TreatmentThis article studies the antiapototic effect of cytokines BAFF & APRIL on the survival of mononuclear cells derived ...Read more
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Prognostic value of MSI status in colorectal cancer patients
Cancer; Prevention, Diagnosis and TreatmentMicrosatellite instability (MSI) causes hereditary non-polyposis colorectal cancer (HNPCC), and occurs in about 15 per c...Read more
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Wound healing effect of Tea tree oil on Methicillin Resistant Staphylococcus aureus (MRSA) : an Animal Study
Microbiology and Infectious DiseasesTea tree oil (TTO), or melaleuca oil, is an essential oil with a fresh camphoraceous odor and a color that ranges from p...Read more
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Controversy in reports about TNF-α (rs361525) related to susceptibility to Hepatocellular Carcinoma (HCC): a meta-analysis
Cancer; Prevention, Diagnosis and TreatmentTumor necrosis factor-α play a very important role in the development and progression of hepatocellular carcinoma. Pre...Read more
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Molecular identification of Aspergillus isolated from livestock feed and poultry using ASAP1 sequencing
Microbiology and Infectious DiseasesThe contamination of livestock feed and poultry with toxic fungi, such as aspergillus in the air and the environment, is...Read more
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The role of cabergoline medicine in treating Cushing's syndrome: A systematic review
Metabolism and Metabolic DiseasesCushing's syndrome is an endocrine disorder caused by the excessive production of corticosteroid hormones and adrenocort...Read more
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Kidney Cancer, Cancer without Early Symptoms
Cancer; Prevention, Diagnosis and TreatmentThe kidneys are a pair of organs in the human body that are located on either side of the spine and in the lower abdomen...Read more
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A simple way for extracting singular porphyrin peaks from total fluorescence spectrum of plasma
Metabolism and Metabolic DiseasesPorphyrins are organic compounds formed from the breakdown of hemoglobin. Any disturbance in porphyrins’ level can be ...Read more
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Mediterranean dietary pattern adherence modify the association between FTO genetic variations and obesity phenotypes
Nutrition and HealthThere is an increasing interest in examining whether dietary patterns modify the association of fat mass and obesity ass...Read more
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Investigating the relationship between metacognitive beliefs, and premenstrual syndrome and depression caused by that, in female students studying at Tehran University of Medical Sciences
Women and Reproductive HealthThe purpose of this research was studying the relation between meta-cognitive beliefs on premenstrual syndrome and depre...Read more
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A study on the interaction of angiotensin I converting enzyme inhibitory peptide with human hemoglobin protein by conductometry method in the absence and presence of a low frequency electromagnetic fi
Metabolism and Metabolic DiseasesHigh blood pressure, or hypertension, is a chronic disease in which the blood pressure goes up. Angiotensin converting e...Read more
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Kisspeptin decreases mean serum adiponectin concentrations in rats
Women and Reproductive HealthKisspeptin/GPR54 signaling system is one of the most important pathways of hypothalamus for regulating reproductive proc...Read more
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Cytotoxicity study of nanoparticles containing aminoglycosides
Nano-Biotech MedicalAminoglycosides are a bunch of antibiotics that inhibit the synthesis of protein in bacteria and lead to eradication of ...Read more
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Effect of Hypiran on the oxidative stress responses in experimental autoimmune encephalomyelitis
Nutrition and HealthExperimental autoimmune encephalomyelitis (EAE) is an animal model of multiple sclerosis. The hallmark of this disease i...Read more
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Non-syndromic obesity in infertile men and structural chromosomal abnormalities
Medical GeneticsObesity is commonly classified into subgroups depending on suspected etiology: monogenic obesity (extremely severe obesi...Read more
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Detection of Mycoplasma hyorhinis contamination in biological products by PCR method
Microbiology and Infectious DiseasesMycoplasmas are the major contributors to biological products and cell lines throughout the world and are easily able to...Read more
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The Approaches for Salivary Glands (SGs) Regeneration: a review
Stem cell and Medical ApplicationsSaliva is secreted from three pairs of major SGs and 100–800 minor SGs and plays a vital role in oral and general heal...Read more
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Evaluation of the effect of saturated and unsaturated fatty acids on the growth and production of outer membrane vesicles in human gut microbiota
Microbiology and Infectious DiseasesA diverse and complex symbiotic microbial community colonize in human host,espicially in the gastrointestinal tract,refe...Read more
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Investigation of microRNAs involved in the EGFR molecular pathway as a biomarker in early detection of colorectal cancer
Medical GeneticsColorectal cancer (CRC) is one of the most common cancers in the world. The highest incidence of CRC in Europe, North Am...Read more
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Aloe Vera Herbal Effects on Diabetes Treatment and Prevention: A Systematic Review
Metabolism and Metabolic DiseasesDiabetes is one of the most common metabolic diseases that affects more than 150 million people in the world. It is the ...Read more
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Isolation and of merkel cell polyomavirus(MCV) in patient with skin cancer
Cancer; Prevention, Diagnosis and TreatmentSkin cancer is the most common malignancy in the world, with high disability and mortality is relatively low (Except for...Read more
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Evaluation of PRC1 gene expression in gastric cancer patients
Cancer; Prevention, Diagnosis and Treatment: Cancer is one of the most important causes of death. Among cancers, gastric cancer is the fourth most common cancer an...Read more
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Effect of Praziquantel Drug on Prevention of Afflicting Dogs with Cestode Echinococcus Granulosus
Microbiology and Infectious DiseasesAwareness of the impact range of praziquantel drug on prevention of afflicting dogs with echinococcus granulosus parasit...Read more
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Omega-3 and its effects on colorectal cancer
Cancer; Prevention, Diagnosis and TreatmentCancer as the second leading cause of death has always been a threat to human life and due to its peculiar nature and la...Read more
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Classification of Genes Related to Infectious Disease: New Hybrid Method for High Imbalanced Data Sets
Medical GeneticsGene functionality explorations has a great importance in health science research. Developing gene classifiers having ac...Read more
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Molecular markers in the diagnosis of lung cancer
Cancer; Prevention, Diagnosis and Treatmentlung cancer is the leading cause of cancer-related mortality, one of the main causes of mortality by 2010. There are sev...Read more
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Osteo therapy and the role of chitosan-alginate in osteoarthritis
Nano-Biotech MedicalOsteoarthritis (OA) is a progressive skeleton disturbance that it is usually related with considerable inability and lim...Read more
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Development and implementation of a novel panel consisting 16 STR markers linked to the HLA-gene-cluster applicable for HLA-typing, PND&PGD
Medical GeneticsPGD (Pre-implantation Genetic Diagnosis) in combination with human leukocyte antigen (HLA) matching, allow not only sele...Read more
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TYCSB culture media reliability for S. mutans isolation
Microbiology and Infectious DiseasesAlthough the clinical significance of dental caries is well recognized, the exact etiology of the condition is not under...Read more
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Higher efficacious delivery in non-toxic dose of Genistein to AML cells by its conjugation on Superparamagnetic Fe3O4 Nanoparticles decorated with bio-compatible Carboxymethylated Chitosan
Nano-Biotech MedicalGenistein is an isoflavone with anti-cancer properties, but effective dosage against malignant cells was not in non-toxi...Read more
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Association Chlamydia trachomatis infection and TNFα -308 polymorphism in abortion
Microbiology and Infectious DiseasesSeveral bacterial infections such as Chlamydia trachomatis and host genetic background, including TNFα SNP polymorphism...Read more
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Poly(A)-tail shortening Length: an Alternative Epigenetic Mechanism for Translational Control of Oncogenes
Medical Genetics: mRNA poly(A) tails in 3'UTR is important for its stability and translation. t is observed Poly(A) tails is dynamic and...Read more
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Frequency of Escherichia coli O157:H7 among children with and without diarrhea stool samples referred to microbiology laboratory of shahid Madani Hospital in KhorramAbad during 2016-2017.
Microbiology and Infectious DiseasesEscherichia coli serotype O157:H7, which has been recognized as a food-borne pathogen occurring worldwide in the recent ...Read more
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Effect of hydroalcoholic leaf extract of Ziziphora tenuior L. on pain in male rats
Microbiology and Infectious DiseasesZiziphora tenuior is one of the traditional medicinal herbs; the main active chemical composition of this herb is an ing...Read more
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studying the effect of silibinin in some of hippo signaling pathway genes , in T47D and MCF7 Breast cancer cell lines with 3D culture.
Cancer; Prevention, Diagnosis and TreatmentBreast cancer is one of the most common malignancy diseases world and is the second leading cause of cancer in women. S...Read more
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Examination of mutations in QRDRs in ParC, ParE genes Salmonella Clinical Examples of Zahedan Hospitals
Microbiology and Infectious DiseasesSalmonellosis is a major public health problem worldwide. Although most Salmonella infections result in mild self-limiti...Read more
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Evaluation of Salmonella.spp in Synovial Fluids of Arthritis Patients by Molecular Method
Microbiology and Infectious DiseasesArthritis is an inflammation of the joints. This complication is often accompanied by pain, swelling, stiffness and heat...Read more
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Investigation of prevalence class 1 and 2 integron gen in Escherichia coli from Isolated clinical samples Tehran’s hospitals
Microbiology and Infectious DiseasesAs the antibiotics are misused, Integrons are the moving genetic factors which carry resistance gens and have an import...Read more
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Blocking of vascular endothelial growth factor signaling through design of bi-specific single domain antibody
Nano-Biotech MedicalOver-expression of vascular endothelial growth factor (VEGF) leads to the proliferation and neovasculature of cancer cel...Read more
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The effect of celastrol on gene expression of TNF-α (Tumor necrosis factor-a) induced by Influenza A virus (PR8/H1N1) in MDCK cells
Microbiology and Infectious DiseasesInfluenza A virus (IAV) can cause acute respiratory distress syndrome, which leading to kill 250000 to 500000 of world ...Read more
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Role of NBD and DBD in P- glycoproteinfunction, a Molecular dynamic simulation
Cancer; Prevention, Diagnosis and TreatmentP-glycoprotein (P-gp) is an ATP-binding cassette (ABC) transporter which belongs to multidrug resistance pump super fami...Read more
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Berberine induced apoptosis of HT-29 cells through mediating of miR-21
Cancer; Prevention, Diagnosis and TreatmentBerberine is an isoquinoline that can be extracted from many medicinal herbs. microRNAs (miRNAs) are small non-coding RN...Read more
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Design, synthesis and application of conjugated gold nanoparticles in photodynamic therapy
Nano-Biotech MedicalPhotodynamic therapy (PDT) has been developed as a novel method for cancer therapy. PDT involves the combined use of a p...Read more
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Green synthesis of Silver nanoparticles by Alhagi camelorum gum
Nano-Biotech MedicalSilver nano particles (AgNPs) are used in textiles, cosmetics, tooth brushes, home appliances, food packages and many ot...Read more
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Evaluation of magnesium & copper levels and antioxidant power in serum of women with endometriosis before and after administration of N-acetylcysteine
Women and Reproductive HealthEndometriosis is caused by the presence of ectopic endometrial stromal outside the endometrial cavity. The oxidative str...Read more
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Some candidate Biomaterials for Amniotic Membranes (AM) Regeneration: a review
Stem cell and Medical ApplicationsAmniotic Membranes (AM) wich form the amniotic sac filled by amniotic fluid and completely surrounds the embryo/fetus. I...Read more
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In silico cancer therapy by using genome editing tool: CRISPR/Cas9
Cancer; Prevention, Diagnosis and TreatmentGiven the fact that cancer today has a broad spectrum of diseases in the populations, and also by relying on the fact th...Read more
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Ginseng For Improving The Quality Of Life In People With Cancer and Fatigue- A Systematic Review
Cancer; Prevention, Diagnosis and TreatmentBackground and purpose: An important issue in cancer health care is the improvement in quality of life (QoL). Physicians...Read more
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A review: Runt-related transcription factor 2 (RUNX2) and its signaling pathways in cardiovascular complications.
Metabolism and Metabolic DiseasesVascular calcification (VC) is a process similar to bone mineralization. VC has been observed in chronic kidney disease,...Read more
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Genetic Diversity and Phylogenetic Analysis of the Iranian Leishmania Parasites Based on HSP70 Gene PCR-RFLP and Sequence Analysis
Microbiology and Infectious DiseasesDespite the broad distribution of leishmaniasis among Iranians and animals across the country, little is known about the...Read more
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Application of Nanomaterials in cosmetic industry
BeautyUsing nanotechnology in various fields, like electronics, medicine, and now in cosmetics applications has expanded. Glob...Read more
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Investigation of A New Paclitaxel Nano Niosomal formulation and Biological Evaluation of Entrapped Paclitaxel on breast cancer cell line
Nano-Biotech MedicalRegarding that the breast adenocarcinoma is the most widespread disease among women, paclitaxel, an anti-cancer drug, co...Read more
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SNP genotyping within INS, INSR, TCF7L2 and PPR- y genes associated with type 2 diabetes in India
Medical GeneticsA pilot population-based study was carried out to evaluate linkage between singlenucleotide polymorphisms within the kn...Read more
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Interference of Dopamine D2 Receptors and Food Restriction on Changing Anxiety Behavior and Serum Biochemical Factors in Adult Male Rats
Nutrition and HealthBackground: Food restriction (FR) and dopaminergic system affect on anxiety behavior, but it has not been determined the...Read more
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Combination of ultrasonic waves and dynamic shear stress by design of a novel perfusion bioreactor for 3D bone tissue engineering
Stem cell and Medical ApplicationsIt is shown that mechanical loading by ultrasound enhanced cell proliferation and differentiation. The aim of present st...Read more
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The effect of 5μM benzoquinone on CXCL12 and KITLG genes in mesenchymal stem cells found in bone marrow niche
Stem cell and Medical ApplicationsChronic exposure to benzene is known to damage the BM resulting in development of different types of leukemia. Extrinsi...Read more
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Reproductive Health Training Program on Students in IRAN: An Action Research Approach
Women and Reproductive HealthTransition from adolescence to adulthood is one of the important periods in the individual life. New behaviors are learn...Read more
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Astaxanthin decreases cell viability in MDA-MB-231, but not in non-tumorigenic human breast cell line MCF 10A
Cancer; Prevention, Diagnosis and TreatmentConsidering the high prevalence of breast cancer in Iran, its rising incidence, and the high mortality rate of patients ...Read more
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Cytotoxic evaluation of cumin essential oil on breast cancer cell line (MCF-7)
Cancer; Prevention, Diagnosis and TreatmentCancer can be considered as one of the genetic diseases that reduces the mortality rate in cancer cells in this disease....Read more
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Antibacterial effects of curcumin encapsulated in micelle nanoparticles on mexX gene expression in ciprofloxacin resistant isolates of Pseudomonas aeruginosa in Guilan
Nano-Biotech MedicalCurcumin, a polyphenolic compound fromturmeric (Curcuma longa) is a pharmacologically safe agent that has antibacterial ...Read more
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Targeting the Brain –Surmounting or Bypassing the Blood–Brain Barrier
Nano-Biotech MedicalTheconstituentsoftheblood–brainbarrier,includingitseffluxtransportersystem,canefficientlylimitbrainpenetrationofpotent...Read more
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Evaluation of H.pylori drug resistance to current cure in North-West of Iran
Microbiology and Infectious DiseasesAlmost half of the world population is infected with Helicobacter pylori, a major risk factor for chronic gastritis, pep...Read more
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Easy and efficient purification of flagellin from salmonella typhimurium ATCC 14028 without necessity of ultracentrifugation
Microbiology and Infectious DiseasesGram negative bacteria's Flagellin has many applications in diagnosis, treatment and vaccines. fliC, the major protein o...Read more
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In silico analysis of Siglec14 as a target for hsa-let-7e-5p
Medical GeneticsSialic acid-binding immunoglobulin-type lectins (Siglecs) are transmembrane proteins that are expressed on the cell surf...Read more
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Effects of administration of trimethoprim/sulfamethoxazole and folic acid on ovarian histopathology in adult female rats
Women and Reproductive HealthPrevious studies have reported the antifertility activities of sulfonamides. This study was designed to evaluate the eff...Read more
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Autism spectrum disorder (ASD) and cancer: both share same genes but different outcomes.
Medical GeneticsAutism spectrum disorder (ASD) is a neurodevelopmental disorder and it is characterized by social and communication prob...Read more
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Current Advances in the Genetic Basis of Rheumatoid Arthritis
Medical GeneticsRheumatoid arthritis (RA) is a chronic inflammatory disease characterized by a distinctive pattern of joint involvement ...Read more
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Determination of physico-chemical properties of Faecalibacterium prausnitzii EVs
Microbiology and Infectious DiseasesFaecalibacterium prausnitzii is one of the most common human gastrointestinal bacteria that has been shown to have sever...Read more
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Lack of association between Hypoxia Inducible Factor rs11549465 polymorphism and Preeclampsia
Medical GeneticsPre-eclampsia (PE) is an obstetric disorder that may result inmaternal and neonatal mortality and morbidity. Placental h...Read more
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Cytotoxic activity of Berberine on the growth of breast cancer cell line (MCF-7)
Cancer; Prevention, Diagnosis and TreatmentMuch research has been conducted on the benefits of various phytochemicals in many herbs, fruits and vegetables and thei...Read more
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Human reovirus destroys liver cancer cell line (Huh-7)
Cancer; Prevention, Diagnosis and TreatmentThe Huh-7 cell line was derived from a liver tumor in a 57-year-old Japanese male patient in 1982. Hepatocellular carcin...Read more
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Cucurbitacin D from Ecballium elaterium (L.) A. Rich upregulates BCL-2 gene in human gastric cancer cell line AGS
Cancer; Prevention, Diagnosis and TreatmentMedicinal plants are potential sources of new drugs and natural therapies based on them are becoming increasingly import...Read more
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Effect of DNA Demethylating Agent Genistein on Epigenetic-modifying Estrogen Receptor Alpha Gene Expression and Apoptosis Induction and also Cell Viability in Hepatocellular Carcinoma HepG 2 cell line
Cancer; Prevention, Diagnosis and TreatmentIn the normal mammalian cells, epigenetic changes such as DNA methylation and histone acetylation play an important role...Read more
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Alterations of gyrA in Enterobacteriaceae isolated of urinary tract infection resistance to quinolones antibiotics
Microbiology and Infectious DiseasesUrinary tract infection is one of the most common infections, which if not treated, it can be cause seriouse problem in ...Read more
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Effect of intracerebroventricular injection of Adenosine on food and fat intake in neonatal chicks
Nutrition and HealthThe present article was aimed to clarify the role of central Adenosine on food intake in neonatal chicks. Adenosine is n...Read more
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β-Cyclodextrin Modified Graphene Oxide Bionanocomposite for pH-sensitive Release of Anti-cancer Drug
Nano-Biotech MedicalGraphene is a multifunctional carbon nanomaterial and could be utilized to develop platform technologies for cancer ther...Read more
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Frequency of Binding Site at C-Terminal of Helicobacter Pylori CagA Separated from Gastric Tissue Biopsy of Patients with Gastroduodenal Disorders in Shafa Hospital in Khorramabad
Microbiology and Infectious DiseasesHelicobacter pylori (H. pylori) is a gram-negative, microaerophilic bacterium in gastric mucosa. It has a helical shape...Read more
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Evaluating Anticancer Effects of Tamarix ramosissima on A549 Cells
Cancer; Prevention, Diagnosis and TreatmentLung cancer is the leading cause of cancer death all over the world. Using plant derived materials as folk remedy has be...Read more
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The association between pre-gravid BMI with fasting glucose and lipid profile in gestational diabetes following Assisted Reproduction.
Women and Reproductive HealthGestational diabetes mellitus (GDM) is one of the most endocrine pregnancy outcomes. High prevalence of GDM was reported...Read more
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Comparison of Antibacterial Activity of Essential Oil of Varieties of Calendula Plant from Varamin (Iran) on Escherichia coli and Staphylococcus aureus
Microbiology and Infectious DiseasesUncontrolled use of conventional antibiotics and synthetic antibacterial medicine has led to the proliferation of microb...Read more
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Effects of serotonin on adiponectin secretion and leptin gene expresions in rats
Women and Reproductive HealthSerotonin is a neurotransmitter which stimulates the secretion of sexual hormones . The nuclei of Hypothalamus involved...Read more
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Comparative investingation of effects of the agricultural pesticides (diazinon and chlorpyrifos) on spermatogenesis in male BALB/c male mice
Nutrition and HealthDiazinon and chlorpyrifos are kind of organophosphate toxins used for agricultural pests. These toxins control acetylch...Read more
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Evaluation of Adiponectin Hormone in Diabetic and Non-diabetic Patients
Metabolism and Metabolic DiseasesAdipose tissue is currently considered as a hormonally active system in the control of metabolism and not only as a stor...Read more
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Effects of 5-aza-2ˈ-deoxycytidine and Valproic Acid on Epigenetic-modifying DNMT1 Gene Expression, Cell Growth Inhibition and Apoptosis Induction in Hepatocellular Carcinoma WCH-17 cell line
Cancer; Prevention, Diagnosis and TreatmentIntroduction DNA molecule of the eukaryotic cells is found in the form of a nucleoprotein complex named chromatin....Read more
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Efficacy of Bone Marrow Mesenchymal Stem Cells and an Amniotic Membrane on the Number of Mast Cells and Degranulation in Random Skin Flaps in Rats
Stem cell and Medical ApplicationsSkin flap procedures are usually used in plastic surgery. Failing can follow, lead to the necrosis of the flap. Therefor...Read more
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Microfluidic 3D cell-Culture platforms for drug response monitoring: potential applications for individualized cancer treatment
Cancer; Prevention, Diagnosis and TreatmentIndividualized monitoring of drug response is supposed as a main constituent of personalized treatment. Current methods ...Read more
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Study of gene expression and promoter methylation pattern of AKAP4 as possible breast cancer diagnostic marker candidate
Cancer; Prevention, Diagnosis and TreatmentBreast cancer is an important health issue for millions of women around the world. Recently, a new group of tumor-associ...Read more
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Investigation Of Antimicrobial Effect Of Magnetical Silver And Silver-Titanium Dioxide Nanocomposites On Commonly Bacteria Of Urinary Infects
Nano-Biotech MedicalRecently, developed nano composite with highly efficient antimicrobial properties are considered. In this study, A new m...Read more
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Fertilization rate would be improved after vitrification of immature mouse oocytes
Women and Reproductive HealthVitrification of oocyte is a promising technique to preserve fertility in different species, but it has deleterious effe...Read more
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Biosynthesis of Silver nanoparticles using water extract of Ziziphus spina_cheristi Leaves
Nano-Biotech MedicalSilver nanoparticles (AgNPs) have been widely used as an antiseptic against a wide range of microorganisms. The goal of ...Read more
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Stress-induced immobility in male and female rats and its effects on offspring numbers, sex ratios and sexual hormones
Women and Reproductive HealthStress-induced immobility inhibition of reproductive functions and can effect on sexual hormones. Increasing/decreasing ...Read more
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Effect of different Electromagnetic fields (EMF) on sperm viability and motility
Women and Reproductive HealthToday, due to the advancement of the level of technology, electromagnetic fields (EMS) from various industries affect...Read more
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A novel role for stem cells in anxiety disorders treatment
Stem cell and Medical ApplicationsAnxiety disorders are the most common mental disorders which has affected one-eighth of the world's population. Patients...Read more
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Anemia, a common disease in hemodialysis patients
Metabolism and Metabolic DiseasesChronic renal failure stage of renal insufficiency it is said that all the no longer able to repel and not toxic waste a...Read more
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Evaluation of serum lipid profiles and oxidative stress indices in sprayer workers
Metabolism and Metabolic DiseasesDirect or indirect contact with pesticides and toxins leads to some biochemical changes, including increasing the produc...Read more
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Evaluation of the interaction between hemoglobin protein and angiotensin-inhibitory peptide by three-dimensional fluorescence method in the absence and presence of low-frequency electromagnetic fields
Metabolism and Metabolic DiseasesMillion people in worldwide are suffering from high blood pressure and related diseases. Over the past two decades, ther...Read more
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The effects of anticancer of 7-hydroxycoumarine on the colon cancer cell line (HT29) and the normal mouse fibroblast cells (L929)
Cancer; Prevention, Diagnosis and TreatmentColorectal cancer it is a lethal and common cancer. due to the development of drug resistance to chemical drugs, the ne...Read more
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Sugar-sweetened beverages increase cardiovascular risk in diabetic patients
Nutrition and HealthSugar sweetened beverages (SSBs) are any type of sugar-added drinks like soft drink, syrup, etc. SSBs consumption has in...Read more
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Silibinin Inhibits miR-17 in Co-cultured HUVECs with A549 Cell Line
Cancer; Prevention, Diagnosis and TreatmentMicroRNAs are involved in different biological processes including cell proliferation and apoptosis, the two intimately ...Read more
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Characterization of a produced monoclonal antibody against testis antigens on the mouse embryogenesis
Medical GeneticsThe complex series of cellular signaling molecules and transcriptional factors are involved in differentiation and devel...Read more
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Progress and Prospect of Nanotechnology in Stem Cells
Nano-Biotech MedicalThe apparition of nanotechnology has paved the way for an obvious understanding of stem cell therapy in vivo and by repe...Read more
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Evaluation of nitrosative stress in sprayer workers
Metabolism and Metabolic DiseasesAgricultural pesticides have an important impact on human health and farmers are people who are more exposed to pesticid...Read more
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The effects of nano-liposomes containing curcumin on the lung cancer cell line.
Nano-Biotech MedicalLung cancer is one of the most common and malignant cancer in both sexes. The prevalence and spread of cancer in iran an...Read more
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Experimental and theoretical investigation on Mandelic acid (R, S) enantioselective separation using Vancomycin chiral column in high performance liquid chromatography
Nano-Biotech MedicalNowadays, antibiotic chiral columns can be used in various chromatography separations. The high potential of these compo...Read more
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The effects of minoxidil on gene expression in the bulb and bulge region of hair follicles by Real time-PCR
BeautyMinoxidil is the most common drug used for treatment androgenic alopecia.Studies have shown that this drug can increase ...Read more
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Genetic variations of Cholesteryl ester transfer protein and diet interactions in relation to lipid profiles and coronary heart disease: A systematic review
Nutrition and HealthThe number of investigations on diet–genotype interactions in the prevention or treatment of dyslipidemia have increas...Read more
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CRISPR/Cas9-mediated designing of lung adenocarcinoma mouse model by method of knock-in
Medical GeneticsMolecular genetic studies in cell and animal models have evolved our knowledge of discovering causal mechanisms relating...Read more
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Synergistic effect of berberine and theophylline on apoptosis induction in MDA-MB-231 cells
Cancer; Prevention, Diagnosis and TreatmentBreast cancer is the most common type of cancer and a leading cause of cancer mortality among women. Berberine is an iso...Read more
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Distribution of Main Variants in Reactions of Cytotoxin vacA of H. pylori in Gastric Biopsy Specimens
Microbiology and Infectious DiseasesHumans have suffered digestive problems for centuries, and we now know that H. pylori are one of their most important ca...Read more
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Evaluation of the HLA-B07 Allelic frequency in the patients with spondyloarthritis syndrome in zanjan province
Medical GeneticsIn 1974 Moll and colleagues established the concept of a group of inter-related disorders originally termed seronegative...Read more
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Association between Heat shock protein 70 gene polymorphism and risk of multiple sclerosis in Iranian population
Medical GeneticsMultiple sclerosis (MS) is a chronic disease of the central nervous system and one of the most common causes of neurolog...Read more
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Matrix metalloprotease-9 (MMP-9) and premature myocardial infarction: A systematic review and meta-analysis
Medical GeneticsCurrent findings on the role of Matrix metalloproteases (MMPs) in cardiac remodelling and the outcome after acute premat...Read more
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Study of PAX5 gene expression in patients with gastric cancer
Cancer; Prevention, Diagnosis and TreatmentGastric cancer is one of the biggest health problems in the world. Due to the lack of many carcinogenic biomarkers and t...Read more
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Suppression of interfering predominant bacteria in purification of Myxobacteria
Microbiology and Infectious DiseasesMyxobacteria have recently gained attention due to the ability to produce numerous biological active metabolites. Applyi...Read more
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Assessment of the dietary intake of Vitamin D and Blood pressure in Elderlies with health care
Nutrition and HealthPopulation studies have demonstrated that there is an inverse association between dietary intake of vitamin D and incide...Read more
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Optical, structural and antibacterial properties assessment of ZnO:Mn nanoparticles
Nano-Biotech Medicalwith the rapid development of human life, controlling the harmful impacts of microorganisms is essential. The current st...Read more
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Nephroprotective effect of Lavandula officinalis L. ethanolic extract in alloxan induced diabetic rats
Nutrition and HealthDiabetes mellitus (DM), a metabolic disorder is a major public health problem in both developed and developing countries...Read more
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NRG1 expression changes in Autism spectrum disorder and play role in executive functions abnormalities
Medical GeneticsAutism spectrum disorder (ASD) is a pediatric heterogeneous psychiatric and neurodevelopment disorder with social and co...Read more
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Relationship of pre-body mass index with umbilical coiling index in gestational diabetes and non-gestational diabetes mellitus.
Metabolism and Metabolic DiseasesIt has been well documented that overweight or obesity before pregnancy is a strong predictor of gestational diabetes me...Read more
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Protective effect of silymarin on plasma membrane and DNA integrity of human sperm treated with cadmium chloride
Women and Reproductive HealthCadmium, as an environmental pollutant, exerts its destructive effects on male reproductive system and sperm by inducing...Read more
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Invitro Effect of Probiotics, Paraprobiotic and Postbiotics of Locally Isolated Lactobacillus casei strains on Colon Cancer Cell Lines
Microbiology and Infectious DiseasesA number of lactic Acid Bacteria (LAB) produce bacteriocin which are bioactive peptides active against a number of path...Read more
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The Evaluation of Methicillin Resistant Staphylococcus aureus (MRSA) Colonization on Skin Lesions in Patients with Psoriasis
Microbiology and Infectious DiseasesPsoriasis is a chronic and inflammatory disease of the skin. Recently, the role of microbial agents in the development o...Read more
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Evaluation of selenium & zinc levels and antioxidant power in serum of women with endometriosis before and after administration of N-Acetylcysteine
Women and Reproductive HealthEndometriosis is characterized by the presence of glands and endometrial stroma outside the uterine and affects approxim...Read more
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An in vitro study on the cytotoxicity of anticancer drug Mitoxantrone on hematopoietic stem cells of bone marrow
Cancer; Prevention, Diagnosis and TreatmentMitoxantrone (Novantrone®; dihydroxyanthracenedione) is a synthetically designed antineoplastic agent and structurally ...Read more
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The prevalence of adeABC encoding genes among Acinetobacter baumannii carbapenem resistant clinical isolates.
Microbiology and Infectious DiseasesAcinetobacter baumannii is the important cause of nosocomial infections worldwide due to its propensity to rapidly acq...Read more
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MYH9 gene and urinary albumin excretion in Iranian diabetic patients
Medical GeneticsDiabetic nephropathy (DN) is one of the most common causes of end stage renal disease (ESRD).: Myosin heavy chain 9 (MYH...Read more
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Application of stem cells in modern therapeutic methods
Stem cell and Medical ApplicationsStem cells are one of the modern therapies being used over recent years to treat diseases such as repairing damaged hear...Read more
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Evaluation of circulating prognostic tumor marker DNA in the blood of brain tumor patients
Cancer; Prevention, Diagnosis and TreatmentRecent evidence suggests that tumor cells may release DNA into the circulation, which is enriched in the serum and plasm...Read more
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Interaction of rs783540 of CPEB1 gene in patients with azoospermia
Medical Genetics: Publicly, 90% of fertile couples get pregnant in one year. Therefore, infertility refers to disability in pregnancy, a...Read more
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Determination Of intestinal Escherichia coli Pathotypes Frequency in Tehran Province By PCR
Microbiology and Infectious DiseasesEscherichia coli (E.coli) is an important member of the normal intestinal microflora for mammals, including humans.Diarr...Read more
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Green synthesis of Gold nanoparticles by water extract of common nettle leaves
Nano-Biotech MedicalGold nano particles (AuNPs) are being considered for cancer treatments for targeted drug delivery in pharmacology and me...Read more
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The Use of Viruses to Treat Cancer
Cancer; Prevention, Diagnosis and TreatmentCancer is an abnormal growth of cells that have lost normal control mechanisms and are able to expand continuously, inva...Read more
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Dexamethasone induced growth inhibition in HT-29 human colorectal cancer cells
Cancer; Prevention, Diagnosis and TreatmentDexamethasone is a type of corticosteroid medication. Dexamethasone has anti-inflammatory effects that are produced via ...Read more
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The Expression Profile of ERBB3 and Its Ligand NRG1 on Depressed Patients Investigation in Hormozgan
Medical GeneticsMajor depressive disorder (MDD), also known simply as depression, is a mental disorder characterized can negatively affe...Read more
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Study of HER2 gene expression in AGS cell line after treatment of cells with Crocus sativus (Iranian Saffron) extract
Cancer; Prevention, Diagnosis and TreatmentThe study of HER-2 gene in cancers, especially gastric cancer, is of great importance. This gene, has been shown to inc...Read more
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Investigating the antitumor activity of PNU-74654 as Wnt/β-catenin inhibitor, alone or in combination with gemcitabine in MiaPaCa-2 pancreatic cancer cell
Cancer; Prevention, Diagnosis and TreatmentWnt/beta-catenin pathway is one of the key dysregulated pathways in several malignancies, including pancreatic cancer (P...Read more
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Hepatoprotective effects of magnesium sulfate on pentylenetetrazol-induced seizures in male Wistar rats
Nutrition and HealthMagnesium is the second most abundant cation (after potassium) in the cell and plays an important role in various biolog...Read more
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the relationship between general and abdominal obesity and advanced glycation end products
Nutrition and HealthAdvanced glycation end products (AGEs) are a heterogeneous group of macromolecules that are formed by the non-enzymatic ...Read more
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The effect of manual acupuncture on anthropometric parameters in obese and overweight patients
Nutrition and HealthObesity is a chronic disease which is on the increase. Treatments of obesity include diet therapy, exercise, behavior th...Read more
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Toxic effects of Selenite and need to bio removal of it
Nutrition and HealthSelenium is an important micronutrient for human and animal health, however it is toxic slightly above homeostatic requi...Read more
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The giant lipoma pediculated in the falciform ligament: a case report
Cancer; Prevention, Diagnosis and TreatmentIntroduction: Lipoma is one of the benign and common tumors of the limbs and trunk that’s rarely occurs in the abdomin...Read more
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The impact of miR-16 and miR-34a overexpression on the migratory and invasive potential of breast cancer cells
Cancer; Prevention, Diagnosis and TreatmentBreast cancer (BC) is the most frequent type of cancer and a main cause of cancer-related deaths among women worldwide. ...Read more
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EXPRESSION OF AN ANTIBODY FRAGMENT (SCFV) AGAINST AMYLOID-BETA USING T7 PROMOTER IN FED-BATCH CULTIVATION MODE
Microbiology and Infectious DiseasesIn the current investigation, the expression yield and solubility of Aβ antibody was analyzed using T7 promoter in fed-...Read more
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One Step Toward Normal Heart Beat By Biological Pacemaker
Medical GeneticsCardiac electrical impulses are generated in sinoatrial node (SAN) which establishes spontaneous action potentials. SAN ...Read more
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Evaluation of cytotoxicity effects and NM23 gene expression against breast cancer T47D cells treated by Zn oxide nanoparticles( ZnNPs)
Stem cell and Medical ApplicationsBreast cancer is the second leading cause of cancer related death worldwide among women. Many investigations have confir...Read more
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Eradication of Cancer Stem Cells through microRNAs: a conceptual view
Cancer; Prevention, Diagnosis and TreatmentmicroRNAs (miRNAs), as 19-24 nucleotides endogenous non-coding RNAs, are involved in the most cellular processes playing...Read more
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Can air pollution impact of sperm parameters? A meta- analysis
Women and Reproductive HealthAir pollution is common in all countries and affects reproductive functions in men and women. It particularly impacts sp...Read more
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Design, production and purification of polyclonal antibodies against recombinant human erythropoietin antigens for immunological investigation of pharmaceutical and clinical samples
Nano-Biotech MedicalIn this research, the primary antibody against erythropoietin is produced by injecting pure recombinant human erythropoi...Read more
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Benefical Effects of hydroalcoholic extract of fenugreek seeds on some Biochemical factors and oxidative stress in high-fructose diet-induced metabolic syndrome in rats
Metabolism and Metabolic DiseasesBackground: Fenugreek (Trigonella foenum graecum) is a traditional herbal plant. seeds of Fenugreek have several propert...Read more
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Prevalence of beta-lactam resistant isolates of Enterobacteriaceae in clinical specimens
Microbiology and Infectious DiseasesBackground: The emergence of extended-spectrum beta-lactamase (ESBL) producing isolates of Enterobacteriaceae has impor...Read more
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Evaluation of cytotoxicity of rainbow trout extracts (Oncorhynchus mykiss) on gastric cancer cell line (AGS)
Cancer; Prevention, Diagnosis and Treatmentrainbow trout due to high levels of essential fatty acids, omega-3 has been identified as one of the important factors i...Read more
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Integrin Beta-3 gene polymorphism and risk for myocardial infarction in premature coronary disease
Medical GeneticsContradictory results have been obtained regarding the role of integrin, beta 3 (ITGB3) gene polymorphisms in occurrence...Read more
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evaluatin of expression of HIF-1alpha gene in various types of colon polyps
Medical GeneticsCancer in iran after cardiovascular diseases and accidents is the yhird leading cause of death. Research has shown that ...Read more
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The role of natural antioxidants in treatment of cancer
Cancer; Prevention, Diagnosis and TreatmentCancer is one of the most common causes of death in advanced industrial societies. With the prevalence and spread of can...Read more
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Molecular study of 92 fetal of couples with recurrent abortion in Mazandaran
Medical GeneticsChromosome abnormalities has recognized as a major factor contributing to pregnancy loss and accounted for about 50% of ...Read more
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analysis of circulating mir-141, and mir-375 in small cell lung cancer patients
Medical Geneticslung cancer is the main cause of mortality from cancer in the world. small cell lung cancer is the most invasive lung ca...Read more
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The effect of mouse recombinant resistin on blood- brain barrier permeability, MDA content and apoptosis in the early stages of focal cerebral ischemia in a stroke mouse model
Metabolism and Metabolic DiseasesThe aim of this study was to evaluate the dose-dependent effects of mouse recombinant resistin on blood-brain barrier(BB...Read more
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Investigation of synergies effects of albumin- amino penicillin on Staphylococcus aureus MRSA
Nano-Biotech Medicalduring the recent decades, Nanotechnology has entered the field of drug industries and importance of nano-drugs in curin...Read more
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The latest developments in pharmaceutical biotechnology
Nano-Biotech MedicalBackground and Aim: Biotechnology has produced over 200 types of drugs and new vaccines that include products for the tr...Read more
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Selection of Peptides Specific to PDL-1 Using Phage Display Technology
Cancer; Prevention, Diagnosis and TreatmentPDL-1 is a well-known antigen to target tumor specifically. It can interact with PD-1 receptor on tumor infiltrating T-l...Read more
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Association between Biochemical Markers BHCG in Screening First Trimester of Pregnancy in Women with PCOS
Women and Reproductive HealthPCOS (polycystic ovary syndrome) is a common endocrine system disease among women of reproductive age. Its prevalence in...Read more
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Fabrication and optimization of polymeric PAA nanoparticles loaded with the natural antibacterial component, curcumin.
Nano-Biotech MedicalCurcumin is a natural polyphenol molecule derived from the Curcuma longa plant which exhibits anticancer, antioxidant, a...Read more
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Evaluation of the HLA-B46 Allelic frequency in the patients with spondyloarthritis syndrome in zanjan province
Medical GeneticsSpondyloarthritis is a group of multi-systematic disorders that has been created by spinal features, peripheral jointsan...Read more
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Crocin suppresses multidrug resistance in MRP overexpressing ovarian cancer cell line
Cancer; Prevention, Diagnosis and TreatmentCrocin, one of the main constituents of saffron extract, has numerous biological effects such as anti-cancer effects. M...Read more
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Survey of beta-lactam hydrolyzing enzymes in Pseudomonas spp. isolated from hospital sewage
Microbiology and Infectious DiseasesBackground: Beta- lactams are the largest group of antibiotics used by hospitals to treat infections caused by Gram-nega...Read more
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Role of Potential tumor marker in several cancer: Diagnostic and Treatment
Cancer; Prevention, Diagnosis and TreatmentTumor markers are substances produced by the tumors or by other cells of the body in response to cancer. They are produc...Read more
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Relation between Resilience and Psychiatric Disorders in Patients with Aids in Bandar Abbas Center for Behavioral Diseases
Nutrition and HealthThe AIDS process is very complex and can significantly affect the physical, social, spiritual and psychological health o...Read more
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Molecular Cloning of Clostridium perfringens Type D & Clostridium septicum vaccine strain epsilon alpha fusion gene in E. coli
Medical GeneticsDesigning and producing a proper fusion construction is the most important problem of producing large quantities of fu...Read more
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Therapeutic effects ellagitannin on non communicable diseases
Nutrition and HealthToday, due to the complications caused by the treatment with chemical drugs, the scientists focus on to use of complemen...Read more
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Modeling premunition for parasites
Microbiology and Infectious Diseases: Here we are interested in premunition that is an immunologic response in host which provides protection toward some pa...Read more
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Evaluation of cytotoxicity, viability and induced oxidative stress by Nickel (II) complex of thiosemicarbazone
Cancer; Prevention, Diagnosis and TreatmentThiosemicarbazones and their metal complexes have significant biological activities including anticancer, antibacterial,...Read more
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Cancer Stem Cell Therapy Based on Nanostructure Drug Vehicle, PMBN-IL3-GA
Nano-Biotech MedicalTo overcome difficulty of cancer treatment by conventional chemotherapy methods, the targeting drug delivery based on Na...Read more
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Investigation of toxicity effect of 4-Mepgc and 4-No2pgc on the K562 cell line (chronic myeloid leukaemia)
Cancer; Prevention, Diagnosis and TreatmentLeukemia is a particular type of cancer characterized by the failure of cell death or disability in the differentiation ...Read more
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Potentiation of mitomycin C-induced apoptosis by lithium chloride in MDA-MB-231 breast cancer cells
Cancer; Prevention, Diagnosis and TreatmentBreast cancer is the principle cause of cancer mortality in females. Mitomycin C (MMC), as a potent antitumor drug, is u...Read more
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Promoter Hypermethylation Analysis of the Tumor Suppressor Gene RASSF1A in Iranian Endometrial Carcinoma Patients
Cancer; Prevention, Diagnosis and TreatmentEndometrial cancer is the most common malignancy among women in developed countries. More endometrial cancers occurs in ...Read more
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Design, modeling and simulation of a novel immunotoxin structure affective against gastrointestinal malignancies
Cancer; Prevention, Diagnosis and TreatmentGastrointestinal malignancies comprise a remarkable proportion of cancer deaths each year. Although many drugs have been...Read more
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Dendrosomal curcumin nanoformulation modulate apoptosis-related genes and protein expression in hepatocarcinoma cell lines.
Nano-Biotech MedicalIntroduction: The side-effects observed in conventional therapies have made them unpromising in curing Hepatocellular c...Read more
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FGF10: Type III Epithelial Mesenchymal Transition and Invasion in Breast Cancer Cell Lines
Cancer; Prevention, Diagnosis and TreatmentMetastasis is one of the important characteristics of a cancer cell. the process called epithelial mesenchymal transitio...Read more
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Neuroprotective nature of adipokine resistin in the early stages of focal cerebral ischemia in a stroke mouse model
Metabolism and Metabolic DiseasesThe goal of the present study was to test the dose-dependent and time-dependent effects of mouse recombinant resistin in...Read more
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Discrimination of Leishmania species by Arginine permease gene AAP3as a suitable molecular tool for detection and genetic proximity analysis
Microbiology and Infectious DiseasesLeishmaniasis presents itself in different clinical manifestations such as: visceral Leishmaniasis, Cutaneous Leishmania...Read more
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Study on protein of leech saliva of Hirudo Oreintalis, Utevsky & Trontelj 2005 in different ages
Nutrition and HealthMedicinal leech, during feeding, enter in host body many bioactive substances that often contain proteins and peptides. ...Read more
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Antiangiogenic Effect of Endostatin-derived Peptides on a Mouse Model of Colon Cancer
Cancer; Prevention, Diagnosis and TreatmentColon Cancer is among the most common malignancies worldwide. Angiogenesis is the formation of new microvasculature thro...Read more
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The effects of specific expression of Apoptin under control of PSES and PSA promoter on apoptosis of LNCaP cells
Cancer; Prevention, Diagnosis and TreatmentApoptotic effects of viral protein Apoptin has been demonstrated in numerous studies. However, its tumor specificity has...Read more
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Development of a chemiluminometric lateral flow biosensor for sensitive detection of Escherichia coli
Microbiology and Infectious DiseasesPaper based nucleic acid testing (NAT) has attracted significant interest in point of care diagnostic field. Lateral flo...Read more
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Neural System Biomarkers
Stem cell and Medical ApplicationsBiomarkers are widely used by physicians, Labradoreans, and scientists. Popular utilization of biomarkers in vivo and in...Read more
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the review of The implications in toxicity Metabolomics of Delta9-tetrahydrocannabinol
Metabolism and Metabolic DiseasesThe plant Cannabis sativa has been used for the effects of its psychoactive resins that name is (cannabinoid δ-9-tetrah...Read more
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Anti-anxiety effects of sinapic acid in NMRI mice
Nutrition and HealthThe present study investigated the anxiolytic effects of sinapic acid on NMRI mice behavior in the elevated plus-maze (E...Read more
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conjugation DNA aptamer HER-2 and anti mir-21 as a pharmaceutical agent targeted for apoptosis in MCF7cancer cell line
Cancer; Prevention, Diagnosis and TreatmentIn the past decade, it has become apparent that certain small RNA plays an important role in the initiation, progression...Read more
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Investigation the effect of low intensity pulsed ultrasound (LIPUS) on proliferation of G 292 osteosarcoma cells on 3D porous PLGA/β-TCP scaffold within perfusion bioreactor
Stem cell and Medical ApplicationsInvestigation the effect of low intensity pulsed ultrasound (LIPUS) on proliferation of G 292 osteosarcoma cells on 3D p...Read more
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Preparation and assessment of chitosan-polyethylenimine-carboxymethyl dextran nanoparticles for efficient siRNA delivery in vitro
Nano-Biotech MedicalAmong polycation nanoparticles, chitosan nanoparticles (Ch) have emerged as promising carriers for gene delivery, nevert...Read more
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The effect of ziziphora extract on the expression of the Claudin_1 gene in the AGS cell line
Cancer; Prevention, Diagnosis and TreatmentClaudins are the main structural and functional proteins of tight junctions in epithelial cells. The altered expression ...Read more
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Association of Cytochrome P450 2C19 (CYP2C19) gene polymorphism and the risk of endometriosis in Iranian population
Women and Reproductive HealthEndometriosis is a chronic disease that is characterized by the occurrence of endometrial glands and stroma outside the ...Read more
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Study genetic susceptibility polymorphisms for chronic lymphocytic leukemia in Iranian population.
Medical GeneticsChronic lymphoid leukemia (CLL) is the most common form of leukemia found in adults. CLL is a monoclonal disorder that w...Read more
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Whole-Exome Sequencing Identifies R1279X of MYH6 to be Associated with Congenital Heart Disease and Other Malformations
Medical GeneticsMyosin VI, encoded by MYH6, is expressed dominantly in human cardiac atria and plays consequential roles in cardiac musc...Read more
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Treatment of vitamin D deficiency in pregnancy
Women and Reproductive HealthThe purpose of this study is the importance of Vitamin D in pregnancy and its treatment. Serum levels of Vitamin D in th...Read more
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Investigation of Infectious Causes of Infertility by Molecular Detection of Mycoplasma hominis in Men's Semen
Microbiology and Infectious DiseasesSince infectious agents are among the important causes of infertility, we decided to identify Mycoplasma hominis in the...Read more
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Biosynthesis of Gold nanoparticles by Areca palm fruit extract
Nano-Biotech MedicalTargeted drug delivery by Gold nano particles (AuNPs) is a new era in pharmaceutical research; i.e. curing tumoral cance...Read more
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The association of the H19 rs217727 polymorphism and Preeclampsia
Medical GeneticsPre-eclampsia is a pregnancy specific disorder; which is defined as pregnancy-induced hypertension and proteinuria. H19 ...Read more
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Design and expression of an immunogenic construct based on calcium sensing receptor antigen
Cancer; Prevention, Diagnosis and TreatmentDue to texture and small size, identifying the parathyroid from thyroid glands is a very difficult procedure. They shoul...Read more
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Sensitivity of levofloxacin in combination with ampicillin-sulbactam and tigecycline against multidrug-resistant Acinetobacter baumannii
Microbiology and Infectious DiseasesDuring the last decades, emergence of antibiotic resistance among A. baumannii has been considered as a worldwide alarm....Read more
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Investigation of cytotoxicity, cell cycle and induction of apoptosis by methyl-thiosemicarbazone complex with Cu2+ in K562 cell line
Cancer; Prevention, Diagnosis and TreatmentThiosemicarbazone compounds have previously been considered as a new series of potent apoptosis-inducing agents. In the ...Read more
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Anticonvulsant, neuroprotective and behavioral effects of magnesium sulfate on pentylenetetrazol-induced seizures in male Wistar rats
Nutrition and HealthMagnesium (Mg2+) is the second most abundant divalent and ubiquitous intracellular cation in mammalian cells and an ess...Read more
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Tuberculosis is a common HIV infection, control and treatment
Microbiology and Infectious DiseasesPoints out Pulmonary that more than all the be without lymph node, pylorus , Urinary tract , bones and joints , meninge...Read more
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Site Directed Mutagenesise of L-Asparagine as an Improveed Anti Cancer Protein with Increased L-ASNase Activity
Cancer; Prevention, Diagnosis and TreatmentL-Asparaginase (L-ASNase) is an FDA approved enzyme which is widely used in fight against acute lymphoblastic leukemia a...Read more
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Anti-Diabetic Effects of Methanolic Extract of Calendula officinalis through Increased Antioxidant Enzymes Activity
Metabolism and Metabolic DiseasesDiabetes is a big challenge in the health care system. ROS generation is the major mechanisms which is involved in the p...Read more
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Association between the CYP2E1 polymorphisms and CML risk in Iranian population
Medical GeneticsPolymorphism in the genes encoding detoxification enzymes results in variability to metabolize carcinogens and cause int...Read more
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Study of matrix metallo proteinase (MMP)-9 gene & its phylogeny tree as a critical gene in metastases
Medical GeneticsThere has been a clear connection between MMPs,ECM degradation & cancer cell invasion. Matrix metalloproteinase(MMP)-9, ...Read more
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Curcumin regulates proinflammatory signaling function of thrombin in endothelial cells
Microbiology and Infectious DiseasesCurcumin regulates proinflammatory signaling function of thrombin in endothelial cells...Read more
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The effect of Rosa canina extract on Bax gene expression in gastric adenocarcinoma cell line(AGS)
Cancer; Prevention, Diagnosis and TreatmentGastric cancer is the most common cancer in the world. It occurs as a result of many factor and there is massive invest...Read more
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Expression of CD74 in Ovarian cancer
Medical GeneticsOvarian cancer is a cancer that forms in or on an ovary. The pro-inflammatory cytokine migration inhibitory factor (MIF)...Read more
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Lack of association between TNF-α rs1800629 polymorphism and Hepatocellular Carcinoma: a meta-analysis
Medical GeneticsTumor necrosis factor a (TNF-α) is a pleiotropic cytokine which can regulate a wide variety of cellular responses. Low ...Read more
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Study of MiRNA-873 expression in Ectopic pregnancy, Endometriosis and Ovarian cancer (review)
Medical GeneticsMicroRNAs are small non-coding RNA molecules that have functions in post-transcriptional regulation of gene expression. ...Read more
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isolates from Kermanshah province submitted at National Animal tuberculosis reference Laboratory at Razi institute
Microbiology and Infectious DiseasesTuberculosis is a zoonotic which has long been recognized and is still one of the most life-threatening diseases. Tuberc...Read more
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Cloning and expressing the chimeric peptide lactoferricin-lactoferampin camel in Lactococcus lactis for promising as a candidate for oral medication
Nutrition and HealthLactococcus lactis is known as probiotics due to its lack of harmful toxins. Because of its high growth potential and re...Read more
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In silico design and analysis of crRNA for post transcriptional regulation of oncogenic miR-128-2 and miR-217 by CRISPR-C2C2 technique.
Medical GeneticsBased on recent studies some microRNAs could have drug resistant effects in turmeric cells during therapy. There are evi...Read more
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Investigation of C-582 A>G polymorphism at beta globin cluster gene in beta-thalassemia patients
Medical GeneticsThalassemia is the most prevalent monogenic disorder worldwide resulting from the inappropriate production of heme. pati...Read more
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Targeted killer gene therapy of breast cancer cells using Pseudomonas exotoxin A
Cancer; Prevention, Diagnosis and TreatmentTargeted expression of killer genes in tumor cells ensures specific elimination of cancer cells with minimal effect on n...Read more
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Evaluation of antioxidant activity and cytotoxicity of an ethanol extract of leaves and fruits of Mespilus germanica on human lung cancer A549 cell line
Cancer; Prevention, Diagnosis and TreatmentLung cancer is the most common cancers and natural products extracted from medicinal plants can play an important role i...Read more
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The nutritional benefits of Pistacia atlantica
Nutrition and HealthPistacia Atlantica Mutica is a genus of the family Anacardiaceae which consist of different parts such as fruit, leave a...Read more
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Interaction of an anti-cancer drug Crizotinib with serum albumin: A docking study
Cancer; Prevention, Diagnosis and TreatmentCancer treatment is one of the major challenges of medical science today. Among them, lung cancer is a common type of ca...Read more
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The Anticancer Effect of Plant Aqueous Extracts of Aloe Vera in Gene Expression Bax and Bcl-2 on Gastric Adenocarcinoma AGS Cells
Cancer; Prevention, Diagnosis and TreatmentGastric cancer is a major cause of cancer death. In terms of incidence is the fourth most common cancer and the second l...Read more
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Impact of CYP3A5 and CYP3A4 genetic polymorphisms on susceptibility risk of chronic myeloid leukemia and treatment response
Medical GeneticsCYP3A5 and CYP3A4 are the members of the CYP3A gene family which metabolizes 50% of therapeutic drugs and steroid hormon...Read more
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Simple solution to prevent prostate cancer
Cancer; Prevention, Diagnosis and TreatmentMen above fifty five years old are at high risk for malignant prostate cancer. Currently surgery is the only treatment a...Read more
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The effect of vinorelbine on HMG proteins in lung cancer A549 cells
Cancer; Prevention, Diagnosis and TreatmentVinorelbine is a semisynthetic vinca alkaloid antitumor drug, widely used in the treatment of cancers such as advanced n...Read more
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Nano ironoxide effects on mouse heart development; a genome wide mRNA level study
Nano-Biotech MedicalNanoparticles have been used for clinical applications such as Hyperthermia, increasing the resolution of magnetic reson...Read more
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The levels of VDBP in patients with chronic rhinosinusitis with polyposis
Medical GeneticsChronic rhinosinusitis (CRS) is a prevalent disease which is characterized by chronic inflammation of the nasal mucosa ...Read more
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Study of DNA binding and cytotoxic activity of a benzochromene derivative
Cancer; Prevention, Diagnosis and TreatmentDNA is currently a target for some of the drugs used in cancer therapy. Among the various treatment strategies for remov...Read more
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Diagnosis of Cytomegalovirus in Sinusitis by Molecular method
Microbiology and Infectious DiseasesCytomegalovirus is one of the important viruses that can cause a wide range of diseases in humans. Sinusitis is a common...Read more
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Motor neuron differentiation potential of human umbilical cord blood- derived mesenchymal stem cells, in vitro
Stem cell and Medical ApplicationsMany people suffer from spinal cord injuries annually. These deficits usually threaten the quality of life of patients. ...Read more
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The role of nutrition in gestational diabetes
Women and Reproductive HealthGestational diabetes is a condition in which blood glucose levels are rising during pregnancy and diabetes symptoms in a...Read more
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Identification of the gene involved in over-production of a novel lipopeptide in an over-expressed mutant of Pseudomonas gingeri
Microbiology and Infectious DiseasesLipopeptides as secondary metabolites, produced by Pseudomonads, can be used as biosurfactants and antimicrobial drugs i...Read more
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Computer aide discrimination of the ovarian lesions by CT scan images
Cancer; Prevention, Diagnosis and TreatmentTo explore diagnostic potential of computerizing texture analysis (TA) methods in discrimination of the normal, benign...Read more
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Evaluation of Acholeplasma laidlawii in biologic products by PCR method
Microbiology and Infectious DiseasesContamination of biological products and cell cultures is one of the important problems in producing a good and safe pro...Read more
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Effect of vitamin E on liver index enzymes in normal and CCl4-intoxified male Wistar rats
Nutrition and HealthVitamin E is the key lipid-soluble antioxidants in humans. Vitamin E supplementation was effective in decreasing markers...Read more
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Microfluidic Nanocomplex-Based Localized Gene Delivery Platform for Bone Tissue Engineering.
Stem cell and Medical ApplicationsAnnually more than 2.2million bone graft procedures take place in worldwide. Biomaterials-based bone tissue engineering ...Read more
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Silver nanoparticles potential as an adjuvant in antimicrobial therapies against multidrug resistant bacteria
Microbiology and Infectious DiseasesThe emergence and rapid spread of multidrug-resistant (MDR) isolates of pathogenic bacteria causing nosocomial infection...Read more
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The Relationship Between Renin- Angiotensin System Genetic Variation and Autism in Iranian Children; A Case –Control Study
Medical GeneticsAutism is a disease of complex nature with a significant genetic component.The importance of Renin-Angiotensin System(RA...Read more
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Using micronuclei assay in cancer treatment
Medical GeneticsCancer is one of the leading causes of illness and mortality worldwide, after cardiovascular disease. There are differen...Read more
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Lantibiotics: New generation of antimicrobial drugs
Microbiology and Infectious DiseasesThese days, due to antibiotic resistance in bacteria, scientists are eager to find new generation drugs. Lantibiotics...Read more
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Identification of Oral strains of Lactobacillus.species in patients with chronic periodontitis and healthy individuals
Microbiology and Infectious DiseasesOral infections constitute some of the most common and costly forms of infections in humans.Chronic periodontitis has be...Read more
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A foundation for universal T-cell based adoptive immunotherapy
Cancer; Prevention, Diagnosis and TreatmentThe patient-specific autologous therapy could be a significant limiting factor in the large-scale exploitation of CAR te...Read more
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A technical overview on the neuronal dysfunction induced by heat stroke on the C57 mice models
Medical GeneticsHeat is an environmental hazard that via increasing core body temperature leads to innate stress with pathological and p...Read more
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Designing and cloning and expression of bean defensin in human embryonic kidney cells and evaluating their antibacterial function
Microbiology and Infectious DiseasesDefensins are among the most important cationic peptides that their presence in a wide range of herbs and animals has be...Read more
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Effect of Staphylococcus aureus isolates in food samples on hep2 cell line
Microbiology and Infectious DiseasesStaphylococcus aureus produces a range of protein-rich toxins and also extracellular pathogens that contribute to bacter...Read more
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Silencing of TIM-3 expression by miR-326 affects apoptosis and proliferation of human HL-60 leukemia cell line
Cancer; Prevention, Diagnosis and TreatmentLeukemia Stem Cells (LSCs) are the main reason for drug-resistance and disease relapse in Acute Myeloid Leukemia (AML). ...Read more
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Performing PGD combined with HLA typing on more than 100 blastomeres
Medical GeneticsPreimplantation genetic diagnosis (PGD) is an option for carrier couples who want to assure their child’s health regar...Read more
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The Effects of MicroRNAs on Bone Regeneration and Differentiation
Medical GeneticsOne of the promising approaches for osteoporosis treatment is bone regeneration. In this case, several therapeutic optio...Read more
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Structural Study of Horseradish Peroxidase upon Interaction with Gold Nanoparticles
Nano-Biotech MedicalRemarkable advancements have been made in the field of nanotechnology, including design of hybrid systems of nanoparticl...Read more
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Effect of hemodialysis on antioxidant enzyme levels in non- diabetic dialysis patients
Metabolism and Metabolic DiseasesDialysis patients are at a high risk for oxidative stress, resulting in an imbalance between the formation of free radic...Read more
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A novel technique to estimate sex ratio in semen
Women and Reproductive HealthOffspring sex is one of the most important factors in controls sex-linked genetically transferred diseases and also for ...Read more
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In silico evaluation of anti-retroviral effects of lactoferrin from different species
Microbiology and Infectious DiseasesLactoferrin (LF) is an iron binding glycoprotein that is present in body fluids and mucosal secretions. Antimicrobial pr...Read more
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Effect of genistein associated with agonist (17-β estradiol) on the viability and apoptosis of human hepatocellular carcinoma HepG2 cell line
Cancer; Prevention, Diagnosis and TreatmentBackground: One of the most lethal cancers is Hepatocellular carcinoma (HCC). Genistein (GE) is a choice compound for tr...Read more
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Qualitative and quantitative evaluation of airborne microorganisms and the concentrations of particulate and respirable matter causing from dust storm in the air of Ilam city: cross sectional study
Microbiology and Infectious DiseasesIntroduction: In recent years, dust storms frequently arrived to have large areas of the western half of Iran. Dust part...Read more
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Preparation and characterization of Nanofibers Using an Electrospinning Technique as ocular drug delivery
Nano-Biotech MedicalFor the treatment of anterior eye segment infections using anti-infective agents, topical ocular application is the most...Read more
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TThe Biological Effects of Aqueous Extract of Ephedra major on the Development of Balb/C Mouse Embryos 7Th to 10Th Days of Pregnancy
Nutrition and HealthAqueous extract of Ephedra major used as a drug for blood pleasure, sleep disorder and lose weight. But it is effects on...Read more
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Mesenchymal stem cells enhance the metastasis of cervical cancer cell line, CaSki, in 3D cell culture system
Cancer; Prevention, Diagnosis and TreatmentMesenchymal stem cells, also known as mesenchymal stromal cells (MSCs), are attractive for repair and regeneration of ti...Read more
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study of mesenchymal stem cell differentiation to chondrocyte on electrospun nanofibrous polyvinyl alcohol alginate sulfat blend
Stem cell and Medical ApplicationsCartilage tissue engineering is used as a potential solution for replacing or repairing damaged tissue. In this method, ...Read more
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COMPARATIVE STUDY OF OLERACEIN E AND OLERACEIN L EFFECTS ON ANTI OXIDANT ACTIVITY, ANTI DIABETIC INDICATORS AND DAMAGE BIOMARKERS LEVELS IN PANCREATIC CELL LINE
Nutrition and HealthThe medicinal plants have valuable biochemical effects. The aim of this study was to assess the effects of Oleracein E a...Read more
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Snake venom: an anticancer agent in immunotoxin therapy
Cancer; Prevention, Diagnosis and TreatmentCancer is the second leading cause of death worldwide. Therefore, many studies are underway to innovate more efficient t...Read more
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Berberine induced cell death of human colon cancer HT-29 through mediating of PARP
Cancer; Prevention, Diagnosis and TreatmentBerberine is an isoquinoline which has many various pharmacological activities, including anticancer activities. Poly (A...Read more
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A brief review of regenerative dentistry
Stem cell and Medical ApplicationsTissue regeneration idea has been formed by stem cells identifying and tissue engineering techniques. Stem cells can be ...Read more
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MOLECULAR DETECTION OF GUT BACTERIA LACTOBACILLUS, BIFIDOBACTERIA, CLOSTRIDIUM DIFFICILE AND YEAST IN BOWEL DISEASE AND CONTROL PATIENTS
Microbiology and Infectious DiseasesTwo kinds of intestinal disorders included inflammatory bowel disease and irritable bowel syndrome have a strong negativ...Read more
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Prevalence of Pediculus capitis among School Children in the Eastern Area of Ahvaz, Southwestern Iran
Microbiology and Infectious DiseasesHead lice are wingless, obligate ectoparasites of humans, which affect millions of children worldwide, especially those...Read more
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Influence of CYP2D6 and CYP3A4 genetic polymorphisms on susceptibility risk of chronic myeloid leukemia and treatment response
Cancer; Prevention, Diagnosis and TreatmentXenobiotic- metabolizing enzymes compose an important line of defence against a variety of carcinogenes and environmenta...Read more
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Antioxidants as DNA protective compounds
Nutrition and HealthBased on the recent findings, antioxidants are some essential factors that can have major role on the health. The human...Read more
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MEDITERRANEAN DIET AND METABOLIC SYNDROME IN DIABETIC SUBJECTS
Metabolism and Metabolic DiseasesType 2 diabetes mellitus (T2DM) increases cardiovascular diseases risk and is a key component of metabolic syndrome (Met...Read more
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TP53 hotspot mutations and expression of c-Myc oncogenes in astrocytoma and meningioma
Medical GeneticsMost studies have shown that there are association between the development and malignancy of brain tumors and tumor supp...Read more
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Effect of Crocin on mitochondrial biogenesis and Oxidative stress in the Striatum of Cholestatic rats
Medical GeneticsOxidative Stress and increment of Mitochondrial Reactive Oxygen Species (ROS) production that occurs in cholestasis whic...Read more
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The effects of sodium butyrate on the expression of HDAC8 gene in HT-29 colorectal cancer cell line
Cancer; Prevention, Diagnosis and TreatmentSodium butyrate (NaB) is a potent growth inhibitor and initiates cell differentiation for many cell types in vitro. In t...Read more
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Detecting of herpes simplex virus’s DNA in the breast tumor, using polymerase chain reaction technique
Medical GeneticsIt has been proven that cancer cells formation can be due to the herpes simplex virus infection in human beings. The ai...Read more
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Detection of Hepcidin biomarker in plasma of patients with stomach tumor before and after treatment
Cancer; Prevention, Diagnosis and Treatment: cancer is a very important public health problem, which is the main cause of death inindustrialized countries and incr...Read more
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Gene Bookmarking, a way to detect, predict and control molecular processes
Medical GeneticsGene bookmarking is a mechanism of epigenetic memory for gene expression transmission programs, during cell division. ...Read more
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Comparison of antimicrobial activity of hydroalcoholic extract of fig(Ficus carica) against Staphylococcus aureus(MSSA & MRSA) with some antibacterial drugs
Microbiology and Infectious DiseasesStaphylococcus aureus is one of the five most common causes of hospital infections and death the worldwide. The excessiv...Read more
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Molcular Detection of Mupirocin Resistance in Staphylococcus aureus
Microbiology and Infectious DiseasesStaphylococcus aureus has become the most common cause of hospital acquired infections over the last few decades. The ba...Read more
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Identification of Gardenerla vaginallis in urine samples of patients with Urinary Tract Infeetion by polymerase chain reaction(PCR) techniques
Microbiology and Infectious DiseasesUrinary tract infection(UTI) is the most common infection and also the second common infection in human societies. Annua...Read more
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Pattern of efflux pump genes in imipenem resistant Acinetobacter isolates
Microbiology and Infectious DiseasesAcinetobacter species are opportunistic pathogens and responsible for various types of nosocomial infections. They are i...Read more
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The Effect of Vitamin D on Diabetes Mellitus: A Systematic Review
Metabolism and Metabolic Diseases: Diabetes Mellitus is a common metabolic and non-infectious disorder that affects around 346 million people worldwide w...Read more
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The Possible Role of B. thetaiotaomicron-derived Outer Membrane Vesicles (OMVs) in the Modulation of Cholesterol Uptake and Diet-induced Obesity
Metabolism and Metabolic DiseasesAltered gut microbiota composition has been proven to be associated with several disorders including metabolic syndrome....Read more
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Managing The Abnormal Papsmear In Pregnancy
Cancer; Prevention, Diagnosis and TreatmentCervical cancer is the most common malignancy diagnosed during pregnancy . The incidence of abnormal pap smear in pregna...Read more
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Diet and lifestyle habit imoact on bone density in postmenopausal women
Nutrition and HealthMenopause is the stage of a woman's life, typically between the ages of 45 and 55, when she stops having menstrual perio...Read more
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Study of Effects of Crushed PLGA Nano-fiber Percentage on The Cell Proliferation in Chitosan-Gelatin-βGlycerophosphate Cartilage Scaffold
Nano-Biotech MedicalArticular cartilage has poor reparative capabilities. So Osteoarthritis is widespread globally in almost 70% of people o...Read more
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Survey of various aspects in polycystic ovary syndrome (PCOS)- A review
Women and Reproductive HealthPolycystic ovary syndrome (PCOS) is a complex endocrine disorder affecting 5–10% of women of reproductive age. It has ...Read more
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Intervention of Dopamine D2 Receptors in Regulating the Serum Lipid Profile in Male Rats under Food Restrictions
Nutrition and HealthStudies have indicated that reduced energy consumption mostly has a significant effect on the reduction of blood lipids...Read more
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Silencing of TIM-3 expression by miR-326 affects apoptosis and proliferation of human HL-60 leukemia cell line
Cancer; Prevention, Diagnosis and TreatmentLeukemia Stem Cells (LSCs) are the main reason for drug-resistance and disease relapse in Acute Myeloid Leukemia (AML). ...Read more